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Found 5 clinical trials
NY-ESO Phase I Study for Prostate Cancer

immune system) is found in many cancers. Proteins such as NY-ESO-1 and LAGE-1 and their fragments are the targets the immune system needs to recognize cancer cells. If the immune system can

  • 142 views
  • 07 Nov, 2020
  • 1 location
Administration of Donor Multi TAA-Specific T Cells for AML or MDS (ADSPAM)

that will train them to recognize the tumor proteins WT1, NY-ESO-1, PRAME, and Survivin, which are expressed on most AML and MDS cancer cells. The cells will be infused at least 30 days post-allogeneic

leukemia
flow cytometry
minimal residual disease
residual tumor
chromosome abnormality
  • 54 views
  • 15 Jun, 2022
  • 2 locations
Cytokine Change in Hepatocellular Carcinoma Treated by Thermal Ablation

Background: Hepatocellular carcinoma (HCC) is the most common primary liver cancer with aggressive tumor behavior. Radiofrequency ablation (RFA) or microwave ablation (MWA) is an effective curative treatment for early stage HCC. This thermal ablation of liver tumor induces host immune response with changes in serum concentration of various cytokines. It …

renal function
cancer
metastasis
  • 2 views
  • 11 Mar, 2022
  • 1 location
A Pilot Trial of Atorvastatin in Tumor Protein 53 (p53) -Mutant and p53 Wild-Type Malignancies

This is a window-of-opportunity trial to determine if atorvastatin given for 1 to 4 weeks at a dose of 80 milligrams per day (mg/day) is sufficient to decrease the level of conformational mutant tumor protein 53 (p53) in malignant diseases (solid tumor and relapsed Acute Myeloid Leukemia (AML)).

leukemia
endocrine therapy
bone marrow procedure
primary cancer
cancer
  • 27 views
  • 04 Jun, 2022
  • 1 location
Core Biopsies for Establishing a Breast Tumor Tissue Repository

This research trial establishes a breast tumor tissue repository from core biopsies. Collecting breast tissue from core biopsies may allow doctors to learn more about the biology of breast cancer and to analyze proteins, genes, and other components of tumor cells. It may also allow doctors to conduct future studies …

tumor cells
cancer treatment
  • 0 views
  • 21 Nov, 2021
  • 1 location