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Found 244 clinical trials
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A Randomized Phase II Trial of Tamoxifen Versus Z-Endoxifen HCl in Postmenopausal Women with Metastatic, Estrogen Receptor Positive, HER2 Negative Breast Cancer

A Randomized Phase II Trial of Tamoxifen Versus Z-Endoxifen HCl in Postmenopausal Women with Metastatic, Estrogen Receptor Positive, HER2 Negative Breast Cancer

tamoxifen
erbb2
estrogen receptor
estrogen
breast cancer
  • 378 views
  • 23 Nov, 2020
  • 1 location
featured
GOG 0225: Can Diet and Exercise Modulate Ovarian, Fallopian Tube and Primary Peritoneal Cancer Progression-Free Survival?

GOG 0225: Can Diet and Exercise Modulate Ovarian, Fallopian Tube and Primary Peritoneal Cancer Progression-Free Survival?

  • 524 views
  • 08 Nov, 2020
  • 1 location
featured
A Randomized Study of Enzalutamide in Patients With Localized Prostate Cancer Undergoing Active Surveillance (ENACT). NCT02799745, 9785-MA-1010.

This is a multicenter, randomized, open label exploratory study, conducted in the US and Canada, evaluating the efficacy and safety of enzalutamide for extension of time to prostate cancer

  • 80 views
  • 02 Sep, 2021
  • 1 location
Cyproterone Acetate in Treating Patients With Newly Diagnosed Stage III or Stage IV Prostate Cancer

cyproterone acetate after tumor progression in treating prostate cancer. PURPOSE: This randomized phase III trial is studying cyproterone acetate to compare how well it works when given

gonadorelin
epinephrine
androgens
endocrine therapy
tumor progression
  • 3 views
  • 07 Nov, 2020
  • 1 location
A Study of Neoadjuvant Hormone Therapy in Patient With Advanced Prostate Cancer Undergoing Radical Prostatectomy.

This is A Multi-centre, Single-arm, Prospective, Interventional Study to Assess Efficacy and Safety of Neoadjuvant Hormone Therapy using Zoladex (Goserelin) and Casodex (Bicalutamide) in Patients with Advanced Prostate Cancer Undergoing Radical Prostatectomy, to assess the efficacy by resectability rate of neoadjuvant hormone therapy (NHT) in subjects with advanced prostate cancer.

  • 0 views
  • 15 Sep, 2021
  • 1 location
TK216 in Patients With Relapsed or Refractory Ewing Sarcoma

Ewing sarcoma is characterized by genomic rearrangements resulting in over-expression of ets family transcription factors driving tumor progression. TK216 is designed to inhibit this effect by

refractory ewing sarcoma
vincristine
  • 2 views
  • 02 Sep, 2021
  • 9 locations
Intrabdominal Hyperthermic Chemotherapy and Pancreatic Cancer

hypothesis considers that using Hyperthermic Intra-abdominal Chemotherapy,HIPEC, with gemcitabine after cytoreductive surgery ,will decrease tumor progression of pancreatic cancer by reducing the neoplastic

  • 30 views
  • 21 Jan, 2021
  • 1 location
Effect of Intratumoral Injection of Gene Therapy for Locally Advanced Pancreatic Cancer

that SSTR2 and DCK::UMK gene transfer demonstrated complementary therapeutic effects to inhibit tumor progression and dissemination, and reduced tumor burden, respectively. On the basis of these

cancer
pancreatic ductal adenocarcinoma
ductal adenocarcinoma
folfirinox
antineoplastic
  • 27 views
  • 24 Jan, 2021
  • 10 locations
An Investigation of Brain Tumor Metabolism in Patients Undergoing Surgical Resection

their treatment course to obtain information about ongoing treatment and response, time to tumor progression and overall survival. These parameters will be used in correlational analysis with the

  • 4 views
  • 11 Apr, 2021
  • 1 location
Evaluation of UCPVax Plus Nivolumab as Second Line Therapy in Advanced Non Small Cell Lung Cancer

survival compared with conventional systemic therapies, they fail to control cancer progression in a significant proportion of patients which can reach up to 50-60% in NSCLC. Recent literature highlights a

  • 0 views
  • 19 Jun, 2021
  • 7 locations