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Found 230 clinical trials
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A Randomized Phase II Trial of Tamoxifen Versus Z-Endoxifen HCl in Postmenopausal Women with Metastatic, Estrogen Receptor Positive, HER2 Negative Breast Cancer

A Randomized Phase II Trial of Tamoxifen Versus Z-Endoxifen HCl in Postmenopausal Women with Metastatic, Estrogen Receptor Positive, HER2 Negative Breast Cancer

HER2
estrogen receptor
estrogen
breast cancer
tamoxifen
  • 378 views
  • 23 Nov, 2020
  • 1 location
featured
GOG 0225: Can Diet and Exercise Modulate Ovarian, Fallopian Tube and Primary Peritoneal Cancer Progression-Free Survival?

GOG 0225: Can Diet and Exercise Modulate Ovarian, Fallopian Tube and Primary Peritoneal Cancer Progression-Free Survival?

  • 524 views
  • 08 Nov, 2020
  • 1 location
Cyproterone Acetate in Treating Patients With Newly Diagnosed Stage III or Stage IV Prostate Cancer

cyproterone acetate after tumor progression in treating prostate cancer. PURPOSE: This randomized phase III trial is studying cyproterone acetate to compare how well it works when given

androgens
epinephrine
gonadorelin
endocrine therapy
gonadotropin
  • 3 views
  • 07 Nov, 2020
  • 1 location
Effect of Tumor Treating Fields (TTFields) (150 kHz) Concurrent With Standard of Care Therapies for Treatment of Stage 4 Non-small Cell Lung Cancer (NSCLC) Following Platinum Failure (LUNAR)

The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of TTFields, using the NovoTTF-100L System, concurrent with standard therapies for stage 4 NSCLC patients, following progression while on or after platinum based treatment.The device is an experimental, portable, battery operated device for …

docetaxel
  • 644 views
  • 19 Oct, 2020
  • 165 locations
TK216 in Patients With Relapsed or Refractory Ewing Sarcoma

Ewing sarcoma is characterized by genomic rearrangements resulting in over-expression of ets family transcription factors driving tumor progression. TK216 is designed to inhibit this effect by

vincristine
refractory ewing sarcoma
  • 0 views
  • 10 Dec, 2020
  • 9 locations
Intrabdominal Hyperthermic Chemotherapy and Pancreatic Cancer

hypothesis considers that using Hyperthermic Intra-abdominal Chemotherapy,HIPEC, with gemcitabine after cytoreductive surgery ,will decrease tumor progression of pancreatic cancer by reducing the neoplastic

  • 30 views
  • 21 Jan, 2021
  • 1 location
Effect of Intratumoral Injection of Gene Therapy for Locally Advanced Pancreatic Cancer

that SSTR2 and DCK::UMK gene transfer demonstrated complementary therapeutic effects to inhibit tumor progression and dissemination, and reduced tumor burden, respectively. On the basis of these

folfirinox
pdac
ductal adenocarcinoma
gemcitabine
metastasis
  • 27 views
  • 24 Jan, 2021
  • 10 locations
Evaluation of UCPVax Plus Nivolumab as Second Line Therapy in Advanced Non Small Cell Lung Cancer

survival compared with conventional systemic therapies, they fail to control cancer progression in a significant proportion of patients which can reach up to 50-60% in NSCLC. Recent literature highlights a

  • 0 views
  • 02 Dec, 2020
  • 7 locations
An Investigation of Brain Tumor Metabolism in Patients Undergoing Surgical Resection

their treatment course to obtain information about ongoing treatment and response, time to tumor progression and overall survival. These parameters will be used in correlational analysis with the

  • 4 views
  • 24 Jan, 2021
  • 1 location
PREoperativ Study of Exercise Training

treatment failure, defined as the risk of not reaching surgery, in patients diagnosed with operable GE cancer. To explore the effect of preoperative exercise training on median time to tumor

esophageal adenocarcinoma
anxiety
tumor progression
adenocarcinoma
depression
  • 3 views
  • 24 Jan, 2021
  • 1 location