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Found 187 clinical trials
Featured trial
A Phase III, randomized, double-blind, placebo controlled, multicenter study to evaluate the efficacy and safety of Etrolizumab as an induction and maintenance treatment for patients with moderately to severe active Crohn's Disease.

A Phase III, randomized, double-blind, placebo controlled, multicenter study to evaluate the efficacy and safety of Etrolizumab as an induction and maintenance treatment for patients with moderately to severe active Crohn's Disease.

  • 180 views
  • 25 Mar, 2021
  • 1 location
Featured trial
A Phase III, Randomized, Double-blind, Placebo-controlled Study of Subcutaneous Secukinumab in Autoinjectors, to Demonstrate Efficacy at 24 Weeks and Long Term Safety and Efficacy up to 3.5 Years in Subjects With Active Psoriatic Arthritis

A Phase III, Randomized, Double-blind, Placebo-controlled Study of Subcutaneous Secukinumab in Autoinjectors, to Demonstrate Efficacy at 24 Weeks and Long Term Safety and Efficacy up to 3.5 Years in Subjects With Active Psoriatic Arthritis

  • 2412 views
  • 23 Nov, 2020
  • 18 locations
A Study of Guselkumab and Golimumab Combination Therapy in Participants With Active Psoriatic Arthritis (AFFINITY)

prior anti-tumor necrosis factor-alpha (anti-TNF-alpha) therapy by assessing clinical response compared with guselkumab monotherapy.

peripheral arthritis
psoriasis
tumour necrosis
spondylitis
psoriatic plaque
  • 5 views
  • 02 May, 2022
  • 27 locations
Guselkumab in Active Psoriatic Arthritis Participants With Inadequate Response/Intolerance to One Prior Anti-TNF Alpha Agent (SOLSTICE)

anti-tumor necrosis factor (TNF) by assessing the reduction in signs and symptoms of PsA.

peripheral arthritis
psoriasis
tumour necrosis
spondylitis
psoriatic plaque
  • 0 views
  • 03 May, 2022
  • 95 locations
Exercise-induced Cardiac Adaptions in Rheumatoid Arthritis Patients During Interleukin-6 vs. Tumor Necrosis Factor Antibody Therapy (RABEX)

The present study will investigative the physiological effects of the cytokines interleukin-6 (IL-6) and tumor necrosis factor (TNF) on the adaptive changes to exercise in patients with

Accepts healthy volunteers
tumour necrosis
tumor necrosis factor
  • 0 views
  • 10 Mar, 2022
  • 1 location
Efficacy of Golimumab in Early Axial Spondyloarthritis in Relation to Gut Inflammation (GO-GUT)

as more need to use anti-tumor necrosis factor therapy and a shorter time to relapse after stopping anti-tumor necrosis factor therapy after obtaining sustained clinical remission. Overall, the

golimumab
remission
factor a
back pain
tumor necrosis factor
  • 3 views
  • 03 Feb, 2022
  • 3 locations
A Study to Assess Disease Activity and Safety of Subcutaneous Lutikizumab (ABT-981) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-Tumor Necrosis Factor (TNF) Therapy

, under armpits, inner thighs, groin and buttocks. Despite the clinical benefit anti-tumor necrosis factor (TNF) therapy offers to patients with HS, there remains a significant unmet medical need for

abscess
  • 7 views
  • 16 May, 2022
  • 18 locations
Biologic Abatement and Capturing Kids' Outcomes and Flare Frequency in Juvenile Spondyloarthritis

This randomized pragmatic trial will generate knowledge about strategies used to de-escalate tumor necrosis factor inhibitor (TNFi) therapy in patients with juvenile spondyloarthritis with

  • 0 views
  • 08 Jan, 2022
  • 1 location
Meal Delivery and Exercise

biomarkers (Interleukin 6 (IL-6), C-reactive protein (CRP), Tumor necrosis factor (TNF-α)) in frail and prefrail homebound older adults before and after the exercise intervention.

  • 0 views
  • 24 Dec, 2021
  • 1 location
Radiofrequency Perineural Injection Idiopathic Carpal Tunnel Syndrome

procedure, one week ,two month and four months after procedure except SNCV and serum CRP and TNF (tumor necrosis factor alpha)will be done before the procedure and after four months only):

tingling sensation
nerve conduction velocity
bupivacaine
ultrasound guidance
paresthesia
  • 0 views
  • 06 Oct, 2021
  • 1 location