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Found 209 clinical trials
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A Phase III, randomized, double-blind, placebo controlled, multicenter study to evaluate the efficacy and safety of Etrolizumab as an induction and maintenance treatment for patients with moderately to severe active Crohn's Disease.

A Phase III, randomized, double-blind, placebo controlled, multicenter study to evaluate the efficacy and safety of Etrolizumab as an induction and maintenance treatment for patients with moderately to severe active Crohn's Disease.

  • 180 views
  • 25 Mar, 2021
  • 1 location
featured
A Phase III, Randomized, Double-blind, Placebo-controlled Study of Subcutaneous Secukinumab in Autoinjectors, to Demonstrate Efficacy at 24 Weeks and Long Term Safety and Efficacy up to 3.5 Years in Subjects With Active Psoriatic Arthritis

A Phase III, Randomized, Double-blind, Placebo-controlled Study of Subcutaneous Secukinumab in Autoinjectors, to Demonstrate Efficacy at 24 Weeks and Long Term Safety and Efficacy up to 3.5 Years in Subjects With Active Psoriatic Arthritis

  • 2367 views
  • 23 Nov, 2020
  • 18 locations
Genetic Polymorphisms of TNF- Promoter and HBV Genotype on Outcome of HBV-Related Chronic Liver Disease

contribute to disease severity. Cytokine gene polymorphism has been regarded affecting prognosis of disease. By detecting HBV genotyping and tumor necrosis factor-alpha polymorphism, this study

carcinoma
tumor necrosis factor
cirrhosis
tumor necrosis factor-alpha
liver disease
  • 0 views
  • 07 Nov, 2020
  • 1 location
UVB-311nm After Initial Slow Response to Adalimumab in Psoriasis

Adalimumab, a fully human anti-tumor necrosis factor (TNF) monoclonal antibody has been approved for the treatment of moderate to severe psoriasis. However, in a portion of cases

adalimumab
tumor necrosis factor
phototherapy
tumor necrosis factor alpha
  • 1 views
  • 07 Nov, 2020
  • 1 location
Immunopheresis Alone or In Combination With Chemotherapy Versus Chemotherapy Alone in Advanced Triple Negative Breast Cancer (TNBC)

Soluble Tumor Necrosis Factor Receptors (sTNF-Rs) from plasma of patients with advanced, refractory Triple Negative Breast Cancer (TNBC) and for disease control when employed as monotherapy, or in

  • 30 views
  • 27 Jan, 2021
  • 6 locations
Meal Delivery and Exercise

biomarkers (Interleukin 6 (IL-6), C-reactive protein (CRP), Tumor necrosis factor (TNF-)) in frail and prefrail homebound older adults before and after the exercise intervention.

  • 0 views
  • 02 Sep, 2021
  • 1 location
Evaluation of PET CT in the Management of Patients With Crohn's Disease.

this condition, uptake has been correlated with local stimulation of tumor necrosis factor, and with monocyte priming and activation. A physiologic variable uptake may be observed in the

tumor necrosis factor
tumor necrosis factor alpha
tumour necrosis
remission
inflammatory bowel disease
  • 15 views
  • 07 Nov, 2020
  • 1 location
Can a Modified Fat Diet With Low Glycaemic Load Improve Insulin Sensitivity and Inflammatory Mediators in Overweight People With Chronic Heart Failure?

distance and Heart Failure Quality of Life [HF QOL] Questionnaire) - body weight - inflammatory mediators (tumor necrosis factor [TNF] alpha, C-reactive protein [CRP

chronic heart failure
  • 16 views
  • 07 Nov, 2020
  • 1 location
Topical Infliximab for Sterile Corneal Melt

necrolysis or mucous membrane pemphigoid. Infliximab is an antibody against tumour necrosis factor alpha and has been used to treat or prevent corneal melt in certain patients with inflammatory of

  • 8 views
  • 03 Feb, 2021
  • 2 locations
Rotation or Change of Biotherapy After TNF Blocker Treatment Failure for Axial Spondyloarthritis

population. Tumor necrosis factor (TNF) was the first target defined in axSpA. Since one third of axSpA patients failed to the first TNF blocker, many axSpA patients received a second biological Disease

fusion protein
il-23
monoclonal antibodies
anti-rheumatic drugs
psoriatic arthritis
  • 17 views
  • 04 Aug, 2021
  • 35 locations