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Found 186 clinical trials
Individualized Fortification of Human Milk for Infants Born ≤ 1250 g (MaxiMoM-InForM)

. At 4 months CA, growth and body composition will be determined by air displacement plethysmography and processing speed by electroencephalography on a subset of infants. Neurodevelopment will be

  • 19 Apr, 2022
Perioperative Versus Postoperative CapOX Chemotherapy for Locally Advanced Colon Cancer

neoadjuvant chemotherapy. The sooner the systemic chemotherapy is received, the better suppression it has on activity of tumor growth factors. Pre-operative chemotherapy may eliminate tiny metastases. It may

  • 25 Feb, 2022
  • 1 location
A Safety Lead-In/Randomized Phase 2 Study of BMX-001 as a Therapeutic Agent for Treatment of Cancer Patients With Multiple Brain Metastases Undergoing Whole-Brain Radiotherapy

(MBM) undergoing whole brain radiation therapy (WBRT). Preliminary studies have demonstrated that BMX-001 provides protection of normal tissues from radiation-induced injury and augments tumor growth

  • 18 Oct, 2022
  • 4 locations
A Phase 1b Trial Investigating Docetaxel Combined With Cirmtuzumab in Patients With Metastatic Castration Resistant Prostate Cancer

the non-canonical Wnt pathway and is suspected to contribute to prostate cancer growth and progression.

  • 20 Oct, 2022
  • 1 location
Olaparib for PAH: a Multicenter Clinical Trial (OPTION)

can reverse PAH in several animal models1. Interestingly, PARP1 inhibition is also cardioprotective. Olaparib, an orally available PARP1 inhibitor, can reverse cancer growth in animals and humans with

body mass index
serum pregnancy test
  • 09 Jun, 2022
  • 3 locations
Study of Biomarkers in Gynecological Cancers

. Further research is needed to better understand the changes found in cancer cells and how to target them to stop or reduce cancer growth. A drug that may be able to block certain specific cancer

cancer care
  • 26 Feb, 2022
  • 1 location
A Phase I Tolerability, Safety, Pharmacokinetics and Preliminary Efficacy Study of Oral Monepantel in Individuals With Motor Neurone Disease

cellular signaling system controlled by mammalian target of rapamycin (mTOR). This stops cancer growth and reduces protein accumulation in diseased cells. PharmAust has already tested monepantel in humans

  • 28 Oct, 2022
  • 2 locations
Protective Effects of the Nutritional Supplement Sulforaphane on Doxorubicin-Associated Cardiac Dysfunction

DOX cardiotoxicity, enhances survival and enhances the effects of DOX on cancer growth in a rat breast cancer model. The investigators suspect that SFN affects DOX metabolism in cancer cells to

  • 04 Oct, 2022
  • 1 location
68Ga-FAP-RGD PET/CT : Dosimetry and Preliminary Clinical Translational Studies

As an new dual targeting PET radiotracer, 68Ga-FAP-RGD is promising as an excellent imaging agent applicable to various cancers. In this study, we observed the safety, biodistribution and radiation dosimetry of 68Ga-FAP-RGD in patients with various types of cancer and compared them with the results of 68Ga-FAPI-02 or 18F-FDG imaging …

primary cancer
pet/ct scan
  • 07 Oct, 2022
  • 1 location
Carbon Ion Re-Radiotherapy in Patients With Recurrent or Progressive Locally Advanced Head-and-Neck Cancer

After multimodal therapy of head-and-neck tumors, patients often develop local recurrence, locally progressive disease or second primary tumors. In this highly pre-treated patient cohort, therapeutic options are limited. Patients that are not candidates for salvage surgery may benefit from re-irradiation. Despite recent technical advances, re-irradiation is associated with severe side …

  • 18 Oct, 2021
  • 1 location