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Found 257 clinical trials
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A Phase II-R and A Phase III Trial Evaluating Both Erlotinib (Ph II-R) and Chemoradiation (PhIII) as Adjuvant Treatment for Patients with Resected Head of Pancreas Adenocarcinoma

A Phase II-R and A Phase III Trial Evaluating Both Erlotinib (Ph II-R) and Chemoradiation (PhIII) as Adjuvant Treatment for Patients with Resected Head of Pancreas Adenocarcinoma

erlotinib
adenocarcinoma
  • 182 views
  • 24 Nov, 2020
  • 1 location
IRCI Gynae Sarcomas High Grade Uterine Sarcoma

This study aims to investigate a drug called Cabozantinib which belongs to a family of drugs that have effects on tumour growth, blood supply, invasion and spread. Therefore, we want to

  • 52 views
  • 23 Jan, 2021
  • 10 locations
Irinotecan With or Without Panitumumab or Cyclosporine in Treating Patients With Advanced or Metastatic Colorectal Cancer That Did Not Respond to Fluorouracil

. Cyclosporine may help irinotecan work better by making tumor cells more sensitive to the drug. Monoclonal antibodies, such as panitumumab, can block tumor growth in different ways. Some block the

fluorouracil
tumor cells
monoclonal antibodies
tumor growth
irinotecan
  • 129 views
  • 07 Nov, 2020
  • 12 locations
Combination Chemotherapy and Trastuzumab in Treating Women With Stage I Stage II or Stage III HER2-Positive Breast Cancer

as trastuzumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing

trastuzumab
adjuvant therapy
tumor cells
cyclophosphamide
immunostimulant
  • 33 views
  • 07 Nov, 2020
  • 1 location
CMAB009 Combined With FOLFIRI First-line Treatment in Patients With RAS/BRAF Wild-type Metastatic Colorectal Cancer

block tumor growth in different ways. Giving combination chemotherapy together with CMAB009 as first treatment after diagnosis of a metastatic colorectal cancerfirst-line treatmentmay improve the

adenocarcinoma of colon
metastasis
BRAF
folfiri regimen
leucovorin
  • 3 views
  • 25 Jan, 2021
  • 2 locations
Bevacizumab and Combination Chemotherapy in Treating Patients With Previously Untreated Metastatic Colorectal Cancer That Cannot Be Removed By Surgery

RATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help

combination chemotherapy
adjuvant therapy
calcium
tumor cells
leucovorin
  • 7 views
  • 07 Nov, 2020
  • 1 location
Perioperative Versus Postoperative CapOX Chemotherapy for Locally Advanced Colon Cancer

neoadjuvant chemotherapy. The sooner the systemic chemotherapy is received, the better suppression it has on activity of tumor growth factors. Pre-operative chemotherapy may eliminate tiny metastases. It may

  • 3 views
  • 21 Jan, 2021
  • 1 location
A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

The purpose of this study is to assess the efficacy of the amivantamab and lazertinib combination, compared with osimertinib, in participants with epidermal growth factor receptor (EGFR) mutation (Exon 19 deletions [Exon 19del] or Exon 21 L858R substitution) positive, locally advanced or metastatic non-small cell lung cancer (NSCLC).

epidermal growth factor
cancer treatment
epidermal growth factor receptor
solid tumour
growth factor
  • 27 views
  • 11 Apr, 2021
  • 298 locations
A Trial for Treatment of Cancer Patients With Multiple Brain Metastases Undergoing Whole-Brain Radiotherapy

(MBM) undergoing whole brain radiation therapy (WBRT). Preliminary studies have demonstrated that BMX-001 provides protection of normal tissues from radiation-induced injury and augments tumor growth

  • 13 views
  • 15 Feb, 2021
  • 3 locations
Bevacizumab and Interleukin-2 in Treating Patients With Metastatic Kidney Cancer

RATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help

tumor cells
white blood cell count
metastasis
platelet count
interleukin-2
  • 17 views
  • 07 Nov, 2020
  • 2 locations