Found 2189 clinical trials
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Phase 1 trial
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Accepting Seniors
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Accepting adults
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Currently Recruiting
HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma
Gene transfer is a new cancer therapy takes white blood cells from a person and grows them in a lab. The cells are changed with a virus to attack tumor cells, then returned to the person
- 144 views
- 22 Dec, 2020
- 1 location
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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Hematology
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Currently Recruiting
A Pilot Phase II Study Using Ibrutinib and Short-Course Fludarabine in Previously Untreated Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
Background: Chronic lymphocytic leukemia (CLL) and/or small lymphocytic lymphoma (SLL) are tumors of abnormal B cells that often affect elderly patients. Studies have identified critical factors required for the growth of CLL cells. First, CLL cells survive because they receive signals through the B-cell receptor. Second, CLL cells benefit from …
- 69 views
- 15 Apr, 2019
- 1 location
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Unknown Phase
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Accepting Seniors
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Accepting adults
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Hematology
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Currently Recruiting
Ibrutinib, Fludarabine, and Pembrolizumab in High-Risk or Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Background: Chronic lymphocytic leukemia (CLL) is a cancer of white blood cells. It is also called small lymphocytic lymphoma (SLL). It causes tiredness, night sweats, weight loss, swollen lymph nodes, easy bruising or bleeding, and frequent infections. Researchers want to test if a drug combination is effective and safe for …
- 47 views
- 23 Nov, 2020
- 1 location
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Phase 3 trial
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Accepting pediatric ages
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Accepting adults
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Pulmonary/Respiratory Diseases
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Currently Recruiting
A Randomized, Multicenter, Double Blind, Phase 3 Study of Nivolumab, Nivolumab in Combination with Ipilimumab, or Placebo as Maintenance Therapy in Subjects with Extensive-Stage Disease Small Cell Lung Cancer (SCLC) after Completion of Platinum-based First Line Chemotherapy
A Randomized, Multicenter, Double Blind, Phase 3 Study of Nivolumab, Nivolumab in Combination with Ipilimumab, or Placebo as Maintenance Therapy in Subjects with Extensive-Stage Disease Small Cell Lung Cancer (SCLC) after Completion of Platinum-based First Line Chemotherapy
- 432 views
- 23 Nov, 2020
- 1 location
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Phase 3 trial
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Accepting pediatric ages
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Accepting adults
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Currently Recruiting
An Open-Label, Randomized Phase 3 Trial of Nivolumab, or Nivolumab plus Ipilimumab or Nivolumab plus Platinum Doublet Chemotherapy versus Platinum Doublet Chemotherapy in Subjects with Chemotherapy-Naïve Stage IV or Recurrent Non-Small Cell Lung Cancer (NSCLC)
An Open-Label, Randomized Phase 3 Trial of Nivolumab, or Nivolumab plus Ipilimumab or Nivolumab plus Platinum Doublet Chemotherapy versus Platinum Doublet Chemotherapy in Subjects with Chemotherapy-Naïve Stage IV or Recurrent Non-Small Cell Lung Cancer (NSCLC)
- 182 views
- 23 Nov, 2020
- 1 location
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Unknown Phase
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Accepting pediatric ages
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Currently Recruiting
A Biomarker-Driven Master Protocol for Previously Treated Squamous Cell Lung Cancer (SWOG S1400)
A Biomarker-Driven Master Protocol for Previously Treated Squamous Cell Lung Cancer (SWOG S1400)
- 104 views
- 23 Nov, 2020
- 1 location
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Phase 3 trial
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Accepting pediatric ages
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Accepting adults
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Currently Recruiting
A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers
A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers
- 232 views
- 24 Nov, 2020
- 1 location
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Phase 2 trial
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Accepting pediatric ages
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Accepting adults
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Family Medicine
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Currently Recruiting
A Randomized Phase II Trial of Tamoxifen Versus Z-Endoxifen HCl in Postmenopausal Women with Metastatic, Estrogen Receptor Positive, HER2 Negative Breast Cancer
A Randomized Phase II Trial of Tamoxifen Versus Z-Endoxifen HCl in Postmenopausal Women with Metastatic, Estrogen Receptor Positive, HER2 Negative Breast Cancer
- 378 views
- 23 Nov, 2020
- 1 location
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Phase 1 trial
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Accepting pediatric ages
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Accepting adults
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Currently Recruiting
Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)
Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)
- 92 views
- 23 Nov, 2020
- 1 location
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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Currently Recruiting
A Phase 2 Study of Sitravatinib in Combination with Nivolumab in Patients with Advanced or Metastatic Urothelial Carcinoma (516-003)
system to recognize and attack cancer cells. This study will evaluate whether the combination of immune system stimulation caused by sitravatinib and improved recognition of tumor cells
- 80 views
- 23 Dec, 2020
- 1 location