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Found 260 clinical trials
Novel Combination Therapy for Osteoporosis in Men

Osteoporotic fractures are a key health problem in older men. Although there are drugs approved to treat osteoporosis in men [bisphosphonates, denosumab, and teriparatide (TPTD) or PTH(1-34)], there is a lack of knowledge on how to use them effectively. TPTD is a potent bone anabolic drug, meaning that it builds …

  • 2 views
  • 27 Jan, 2021
  • 1 location
Value of Inhaled Treatment With Aztreonam Lysine in Bronchiectasis

A randomised controlled trial of the safety, tolerability and effectiveness of 2 doses of Cayston (Aztreonam Lysine) compared to placebo in participants with bronchiectasis. Bronchiectasis not due to cystic fibrosis is a chronic inflammatory disease characterised by cough, sputum production and frequent respiratory tract infections. There are currently no licensed …

  • 7 views
  • 15 Feb, 2021
  • 6 locations
Kharituwe TB Contact Tracing Study

The purpose of this study is to characterize the role of human mobility in fueling TB epidemics and estimate the potential impact of innovative case finding interventions tailored to mobile

  • 0 views
  • 23 Feb, 2021
  • 2 locations
Validation of a Tuberculosis Treatment Decision Algorithm in HIV-infected Children (TB-Speed HIV)

presumptive TB. It will be conducted in four countries with high and very high TB (Tuberculosis) incidence (Cte d'Ivoire, Uganda, Mozambique, and Zambia) which have not participated in the study that

  • 0 views
  • 23 Jan, 2021
  • 6 locations
Using Biomarkers to Predict TB Treatment Duration

Background Tuberculosis (TB) is a bacterial lung infection. Typical treatment using anti-TB drugs lasts about 6 months. Some people with less severe TB might not

chest x-ray
ethambutol
cough
vasectomy
x-rays
  • 276 views
  • 07 Mar, 2021
  • 17 locations
TB Screening Improves Preventive Therapy Uptake

HIV-infected people have an increased risk of developing active tuberculosis (TB). To reduce the burden of TB among people living with HIV (PLHIV), the World Health Organization (WHO) recommends

  • 0 views
  • 27 Jan, 2021
  • 1 location
Drinkers' Intervention to Prevent Tuberculosis (DIPT Study)

There is an urgent global need to decrease the high mortality of tuberculosis (TB) in persons with HIV as TB is the leading cause of death among persons with HIV worldwide. The DIPT (Drinkers

skin test
isoniazid
tuberculosis
antiretroviral agents
heavy drinking
  • 15 views
  • 25 Jan, 2021
  • 2 locations
Community-based Tuberculosis Tracing and Preventive Therapy

The many gaps observed in the cascade of care of tuberculosis (TB) child contacts occur mostly in the screening, preventive therapy (PT) initiation and PT completion steps and the main drivers

rifampin
isoniazid
  • 0 views
  • 23 Jan, 2021
  • 31 locations
Options for Delivering Isoniazid-Rifapentine (3HP) for TB Prevention (3HP Options Implementation Trial)

The Options for Delivering Isoniazid-Rifapentine (3HP) for TB Prevention (3HP Options Implementation Trial) study will be a three-arm, open-label, parallel, randomized trial. This hybrid

HIV Infection
rifapentine
isoniazid
  • 0 views
  • 25 Jan, 2021
  • 1 location
BCG Revaccination of Healthy Adolescents for the Prevention of Mycobacterium Tuberculosis Sustained Infection

The purpose of this study is to demonstrate the efficacy of Bacille Calmette Guerin (BCG) revaccination against sustained Mycobacterium tuberculosis infection versus placebo in previously BCG

mycobacterium tuberculosis
vaccination
bcg vaccine
  • 84 views
  • 29 Jan, 2021
  • 5 locations