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Found 217 clinical trials
Tuberculosis Preventive Therapy Among Latent Tuberculosis Infection in HIV-infected Individuals

The investigators want to know if ultra-short, effective treatment for latent tuberculosis (TB) infection (LTBI) could dramatically reduce the global incidence of active TB or not. The

  • 13 Apr, 2022
  • 1 location
Improve Treatment Outcomes for Tuberculosis Infection in Tertiary Care Hospitals

Early diagnosis can contribute to good treatment outcomes and isolate infection control.

  • 11 Apr, 2022
  • 4 locations
Tuberculosis (TB) Aftermath

TB Aftermath will compare effectiveness, cost-effectiveness and feasibility of two ACF strategies that are presently being considered by the RNTCP for detecting recurrent TB and provide evidence needed to implement and scale the preferred intervention. The proposed study will address this gap, through the following specific aims: Primary Aim 1: …

Accepts healthy volunteers
  • 12 May, 2022
  • 1 location
Community-based Tuberculosis Tracing and Preventive Therapy (CONTACT)

The many gaps observed in the cascade of care of tuberculosis (TB) child contacts occur mostly in the screening, preventive therapy (PT) initiation and PT completion steps and the main drivers

  • 26 Feb, 2022
  • 22 locations
eNose-TB: Electronic Nose for Tuberculosis Screening

An electronic-nose (e-nose) had been investigated as a diagnostic tool for tuberculosis by examining exhaled breath of the patients. Universitas Gadjah Mada has developed an e-nose device for TB

Accepts healthy volunteers
  • 22 Apr, 2022
PredictEndTB Signature for Individualizing Treatment in Multidrug-Resistant Tuberculosis

utilize the transcriptomic signature-based model compared to the standardised twenty months treatment in a cohort of multidrug-resistant tuberculosis patients.

  • 14 Apr, 2021
  • 5 locations
Evaluation of Efficacy and Safety of VPM1002 in Comparison to BCG in Prevention of Tb Infection in Infants

The trial is designed as a phase III, double-blind, multicenter, randomized, single administration, active-controlled, parallel-group design with two groups of newborn infants receiving either VPM1002 or BCG SII (1:1 allocation) to assess the efficacy, safety and immunogenicity of VPM1002 against Mtb infection.

Accepts healthy volunteers
  • 26 Oct, 2021
  • 14 locations
Xpert Active Case-finding Trial 3 (XACT-3)

TB remains the foremost infectious disease killer globally. A startling statistic is that two out of every five TB cases globally (40%) remain undiagnosed and untreated. These 'missed' or undiagnosed cases are disproportionately concentrated in large peri-urban 'slums' and informal settlements of large cities in Africa and Asia (they are …

  • 05 Apr, 2021
  • 4 locations
Study of the Safety and Efficacy of the Subunit Recombinant Tuberculosis Vaccine GamTBvac

This is a multicenter, double-blind, randomized (in 1:1 ratio) placebo-controlled study to assess the safety and protective efficacy of the subunit recombinant tuberculosis vaccine GamTBvac

Accepts healthy volunteers
  • 25 Mar, 2022
  • 1 location
Rapid Research in Diagnostics Development for TB Network (R2D2TB Network)

To reduce the burden of TB worldwide through more accurate, faster, simpler, and less expensive diagnosis of TB Every year, more than 3 million people with TB remain undiagnosed and 1 million die. Better diagnostics are essential to reducing the enormous burden of TB worldwide. The Rapid Research in Diagnostics …

  • 22 Mar, 2022
  • 11 locations