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Found 260 clinical trials
Treatment Shortening of MDR-TB Using Existing and New Drugs

)' and 'the standard treatment regimen including injectables for 20 to 24 months (control arm)' for treating fluoroquinolone-sensitive multidrug-resistant tuberculosis.

treatment regimen
delamanid
linezolid
pyrazinamide
levofloxacin
  • 0 views
  • 22 Jan, 2021
  • 1 location
Effect of Public Sector Antiretroviral Treatment Programme on Tuberculosis and Immunization Care

. The purpose of this study is to compare the performance of tuberculosis (TB) and childhood immunization programmes in primary care facilities participating in the South African national

antiretroviral agents
  • 1 views
  • 07 Nov, 2020
  • 1 location
NAT2 in Re-challenge of INH in Patients With Hepatitis

Apply the information of NAT2 genotyping into the re-challenge protocol of INH titration in patients with anti-TB medication induced hepatitis.

isoniazid
hepatitis
  • 5 views
  • 07 Nov, 2020
  • 38 views
  • 04 Feb, 2021
  • 3 locations
Study on the Management Model of "Home Treatment" for Tuberculosis Patients

This project aims to standardize the management of "home treatment" for tuberculosis patients, improve the compliance of patients with treatment, reduce the risk of transmission, and study the

  • 0 views
  • 23 Jan, 2021
  • 1 location
Early Bactericidal Activity of Rifampin + Meropenem + Amoxicillin/Clavulanate in Adults With Pulmonary TB

The overall goal of this exploratory proof-of-concept study is to determine whether, in participants with pulmonary tuberculosis caused by M. tuberculosis (MTB) with or without rifampin

neutrophil count
cervical cap
platelet count
amoxicillin
direct microscopy
  • 16 views
  • 24 Jan, 2021
  • 1 location
Efficacy of Oral Zinc Administration as an Adjunct Therapy in New Pulmonary Tuberculosis (Category I) Patients

The primary objective of the study is to evaluate the efficacy of oral Zinc administration in new smear positive pulmonary tuberculosis patients. Evidence is available suggesting that

smear
zinc
sputum smear
  • 9 views
  • 07 Nov, 2020
  • 1 location
Drug Exposure and Safety of a Shorter Tuberculosis Treatment Based on High-Dose Rifampicin and Pyrazinamide

Tuberculosis (TB) treatment is long and complex with the risk of poor treatment adherence and treatment failure. Several attempts to shorten treatment of drug-susceptible TB have been

  • 0 views
  • 27 Jan, 2021
  • 1 location
Promoting Engagement in the Drug Resistant TB-HIV Care Continuum in South Africa PRAXIS Study

The goal of the proposed study is to enhance adherence and retention in care for M/XDR-TB HIV patients through enhanced standard of care, targeted transition to outpatient medication self

  • 55 views
  • 23 Jan, 2021
  • 1 location
Clinical Study on Adoptive Treatment of MDR-TB With Allogeneic T Cells

Brief summary: Allogeneic T cells from healthy donor will be administrated intravenously to patients with the MDR-TBand then the safety and efficacy of T cells will be evaluated.

  • 0 views
  • 22 Jan, 2021
  • 1 location