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Found 260 clinical trials
Study to Check the Efficacy and Safety of Recombinant BCG Vaccine in Prevention of TB Recurrence

This is a Phase II/III trial with two groups of adults successfully cured of category 1 pulmonary TB receiving either VPM1002 or placebo. Single dose of VPM1002 / placebo will be administered to

  • 58 views
  • 24 Jan, 2021
  • 10 locations
Protecting Households On Exposure to Newly Diagnosed Index Multidrug-Resistant Tuberculosis Patients

The purpose of this study is to compare the efficacy and safety of 26 weeks of delamanid (DLM) versus 26 weeks of isoniazid (INH) for preventing confirmed or probable active tuberculosis (TB

potassium
l aspartate
vasectomy
oophorectomy
atazanavir
  • 137 views
  • 25 Jan, 2021
  • 27 locations
Use of BCG Vaccine as a Preventive Measure for COVID-19 in Health Care Workers

Mycobacterium bovis isolate and is widely used worldwide as a tuberculosis (TB) vaccine, but there are studies demonstrating non-specific immunotherapeutic mechanisms of this vaccine that signal a possible

  • 0 views
  • 27 Jan, 2021
  • 1 location
The Effect of 18-month Regimen Containing 6 Anti-tuberculosis Drugs for Patients With MDR-TB

WHO has recommended that multidrug-resistant tuberculosis (MDR-TB, defined as resistance to at least isoniazid (H) and rifampicin (R) be addressed as a public health crisis and enhance capacity

pulmonary tuberculosis
chest x-ray
sputum culture
extensively drug-resistant tuberculosis
isoniazid
  • 0 views
  • 23 Jan, 2021
  • 20 locations
Early Bactericidal Activity of TBA-7371 in Pulmonary Tuberculosis

The purpose of this study is to assess the safety, early bactericidal activity (EBA) and pharmacokinetics of TBA-7371 in adult participants with rifampicin-sensitive tuberculosis and select dose

direct microscopy
vasectomy
mycobacterium tuberculosis
oophorectomy
sputum collection
  • 1 views
  • 29 Jan, 2021
  • 2 locations
Adjunctive NAC in Adult Patients With Pulmonary Tuberculosis

To determine if adjunctive N-acetylcysteine 1200 mg twice a day (BID) accelerates sputum culture conversion and normalization of cellular glutathione in tuberculosis (TB), and to assess its

smear
sputum culture
tuberculosis treatment
  • 0 views
  • 27 Jan, 2021
  • 1 location
Atorvastatin to Reduce Inflammation After Tuberculosis Treatment Completion

successful TB treatment completion in HIV-infected and HIV-uninfected adults measured by PET/CT.

  • 0 views
  • 27 Jan, 2021
  • 1 location
Assessing PA-824 for Tuberculosis (the APT Trial)

Assess the mycobactericidal activity of PA-824 (given at 200 mg daily) when added to first-line tuberculosis (TB) treatment (isoniazid, pyrazinamide, and a rifamycin antibiotic) over 12 weeks of

rifamycin
ethambutol
pyrazinamide
pa-824
rifampin
  • 198 views
  • 25 Jan, 2021
  • 1 location
Treatment Shortening of MDR-TB Using Existing and New Drugs

)' and 'the standard treatment regimen including injectables for 20 to 24 months (control arm)' for treating fluoroquinolone-sensitive multidrug-resistant tuberculosis.

delamanid
linezolid
levofloxacin
pyrazinamide
treatment regimen
  • 0 views
  • 22 Jan, 2021
  • 1 location
The Individualized M(X) Drug-resistant TB Treatment Strategy Study

This is a randomized controlled clinical trial comparing treatment success of a gene-derived individualized drug-resistant Tuberculosis regimen to a standard Tuberculosis regimen based on South

pulmonary tuberculosis
extensively drug-resistant tuberculosis
antiretroviral
treatment regimen
probe
  • 21 views
  • 15 Feb, 2021
  • 1 location