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Found 82 clinical trials
A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Ulcerative Colitis (UC)

Vedolizumab is a medicine that helps to reduce inflammation and pain in the digestive system. In this study, children and teenagers with moderate to severe ulcerative colitis will be treated with vedolizumab. The main aim of the study is to check if participants achieve remission after treatment with vedolizumab. Remission …

tumor necrosis factor
methotrexate
tumour necrosis
tumor necrosis factor alpha
mercaptopurine
  • 0 views
  • 07 Oct, 2022
  • 62 locations
Enteral Nutrition Tolerance and the Gut Microbiome Study

The current study will enroll patients who are going to require enteral nutrition support for at least 4 weeks and randomize them to standard polymeric formulas or blenderized tube feeding. They

  • 0 views
  • 25 Apr, 2022
  • 1 location
Protein Delivery in Intermittent and Continuous Enteral Nutrition in ICU Patients (ProBoNo)

. Adequate nutrition is the basis for an optimal recovery for ICU patients and for prevention of muscle wasting. Today, continuous feeding is still the standard enteral nutrition form for patients in the ICU

Accepts healthy volunteers
  • 0 views
  • 02 Jul, 2022
  • 1 location
The Influence of Polymeric Versus Oligomeric Enteral Feeding on Tolerance and Nutritional Status in Paediatric Intensive Care (Polygomer)

preferred form of nutritional support is enteral, the more natural form, compared to parenteral. The enteral nutrition is cheaper and is associated with better outcomes and lower incidence of associated

  • 0 views
  • 04 Oct, 2022
  • 1 location
Mucous Fistula Refeeding Reduces the Time From Enterostomy Closure to Full Enteral Feeds ("MUC-FIRE" Trial) (MUC-FIRE)

The primary objective of this study is to demonstrate that mucous fistula refeeding between enterostomy creation and enterostomy closure reduces the time to full enteral feeds after enterostomy closure compared to standard of care.

  • 0 views
  • 24 Apr, 2022
  • 11 locations
Fiber Food Introduction in Pediatric Short Bowel Syndrome

Short bowel syndrome (SBS) is a rare but challenging condition in which patients have insufficient bowel length to meet fluid, electrolyte, and nutrient requirements without parenteral support. The purpose of this study is to determine how well dietary fiber is tolerated in patients with short bowel syndrome compared to patients …

Accepts healthy volunteers
  • 0 views
  • 10 Jul, 2022
  • 1 location
Effect of Blenderized Enteral Tube Feeds on Pediatric Upper Gastrointestinal Tract Physiology

Blenderized diets consist of a wide range of table foods such as fruits, vegetables, meat and legumes, pureed in a blender and administered via gastrostomy tube. In a recent study, the investigators reported that children receiving blenderized feeds via gastrostomy had fewer total admissions and respiratory admissions, total emergency room …

  • 0 views
  • 18 Nov, 2021
  • 1 location
Replacing Protein Via Enteral Nutrition in Critically Ill Patients

The investigator will investigate the effect of supplemental enteral protein (1.2 g/kg/day) added to standard formula to achieve high amount of enteral protein (range 2-2.4 g/kg/day) given from ICU day 5 until ICU discharge up to ICU day 90 as compared to no supplemental enteral protein to achieve moderate amount …

  • 0 views
  • 07 Mar, 2021
  • 2 locations
PRotEin Provision in Critical IllneSs (PRECISe)

whether enteral nutrition with increased protein content in mechanically ventilated, critically ill patients is able to improve functional recovery.

  • 0 views
  • 02 May, 2022
  • 9 locations
Effect of Ileocolonic Delivered Vitamins and an Anti-Inflammatory Diet on Crohn's Disease and Healthy Volunteers (Vita-GrAID)

This study will evaluate if the Groningen Anti-Inflammatory Diet and the ileocolonic delivery of vitamin B2, B3 and C can positively influence the course of Crohn's disease and can positively alter the gut microbiome of Crohn's disease patients as well as healthy volunteers.

crohn's disease
mucosal inflammation
Accepts healthy volunteers
faecal calprotectin
vitamin
  • 0 views
  • 04 Oct, 2022
  • 1 location