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Found 11 clinical trials
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GOG 0275: A Phase III Randomized Trial of Pulse Actinomycin-D Versus Multi-Day Methotrexate for the Treatment of Low-Risk Gestational Trophoblastic Neoplasia

GOG 0275: A Phase III Randomized Trial of Pulse Actinomycin-D Versus Multi-Day Methotrexate for the Treatment of Low-Risk Gestational Trophoblastic Neoplasia

  • 174 views
  • 08 Nov, 2020
  • 1 location
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

mucinous adenocarcinoma Non-epithelial tumors of the ovary: A) Germ cell tumor of ovary B) Mullerian mixed tumor and adenosarcoma (closed to accrual 03/30/2018) Trophoblastic tumor: A

squamous cell carcinoma of the head and neck
bilateral oophorectomy
ultrasound examination
pecoma
cancer other
  • 6048 views
  • 24 Sep, 2021
  • 818 locations
Second Uterine Evacuation for Low-risk Gestational Trophoblastic Neoplasia

To evaluate the efficacy and safety of second uterine curettage in patients with low-risk non-metastatic GTN.

  • 0 views
  • 21 Feb, 2021
  • 1 location
Avelumab and Methotrexate in in Low-risk Gestational Trophoblastic Neoplasias as First Line Treatment

Gestational trophoblastic neoplasias (GTN) are characterized by the persistence of elevated hCG titers after complete uterine evacuation of a partial hydatidiform mole (PHM) or a complete

  • 10 views
  • 24 Jan, 2021
  • 6 locations
Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic Neoplasia

gestational trophoblastic neoplasia. It is not yet known whether multi-day methotrexate protocol is as effective as biweekly single-dose actinomycin D protocol in treating patients with gestational

gonadotropin
serum bilirubin
  • 0 views
  • 25 Jan, 2021
  • 1 location
Study of Hysteroscopic Repeat Curettage as the First-line Treatment in Low-risk Postmolar Gestational Trophoblastic Neoplasia

Study of hysteroscopic repeat curettage as the first-line treatment in low-risk postmolar gestational trophoblastic neoplasia compared with the MTX single drug chemotherapy

total bilirubin
methotrexate
trophoblastic disease
serum bilirubin
  • 29 views
  • 25 Jan, 2021
  • 1 location
Study of Different Therapeutic Strategies in Hydatidiform Mole With Lung Nodule

The purpose of present study is to provide clinical evidences for the appropriate management of molar pregnancy with lung nodule. The hydatidiform mole patients with lung nodule 1.0cm will be randomized into 2 groups: A. treated with chemotherapy immediately, B. follow up until hCG level met FIGO diagnostic criteria of …

hydatidiform mole
  • 38 views
  • 25 Jan, 2021
  • 1 location
Combination of Methotrexate(MTX) and Actinomycin(ACTD) in the Low Risk Gestational Trophoblastic Neoplasma GTN Patients With Score of 5-6

In this study, a prospective, multicenter randomized controlled study was conducted to compare the clinical efficacy and toxicity response of combination MTX+ACTD multi-course regimen in low-risk GTN patients with score 5-6 with standard MTX single-drug multi-course regimen.

  • 0 views
  • 23 Jan, 2021
  • 1 location
Detection of Human Chorionic Gonadotropin by Interferometry in Gestational Trophoblastic Disease

We will try to use the novel analytical technique -Dual Polarisation Interferometry (DPI),to achieve detection the minimal amount of the human chorionic gonadotropin for early detection and strict monitor of the GTD.

  • 2 views
  • 07 Nov, 2020
  • 1 location
The French National Reference Centre of GTD

The French Gestational Trophoblastic Disease (GTD) centre has been set up and active by registering, monitoring and treating women with GTD since november 1999. The aim is to improve the management of trophoblastic disease in France. About 850 new cases are registered each year and 140 women treated, mostly with …

human chorionic gonadotrophin
hydatidiform mole
choriocarcinoma
chest radiography
trophoblastic disease
  • 18 views
  • 21 Jan, 2021
  • 1 location