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Found 14 clinical trials
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GOG 0275: A Phase III Randomized Trial of Pulse Actinomycin-D Versus Multi-Day Methotrexate for the Treatment of Low-Risk Gestational Trophoblastic Neoplasia

GOG 0275: A Phase III Randomized Trial of Pulse Actinomycin-D Versus Multi-Day Methotrexate for the Treatment of Low-Risk Gestational Trophoblastic Neoplasia

  • 239 views
  • 08 Nov, 2020
  • 1 location
Study of PD-1 Antibody and Bevacizumab in the Treatment of High-risk GTN After Combined Chemotherapy

Gestational trophoblastic Neoplasia(GTN) is a kind of malignant tumor in women of childbearing age. It is easy to metastasized through the blood system in the early stage, so it is a relatively

  • 0 views
  • 13 Jun, 2022
  • 1 location
Camrelizumab Plus Apatinib in Patients With High-risk Gestational Trophoblastic Neoplasia

relapsed (Cohort B) gestational trophoblastic neoplasia (GTN). Eligible patients will receive camrelizumab plus apatinib plus chemotherapy. Treatment will be continued until disease progression

  • 0 views
  • 22 Jul, 2022
  • 1 location
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

tumors) (closed to accrual) Clear cell endometrial cancer Clear cell ovarian cancer (closed to accrual) Gestational trophoblastic disease (GTD) Gallbladder cancer

hydrocortisone
cns disease
thyroiditis
undifferentiated carcinoma
monoclonal antibodies
  • 6634 views
  • 10 Aug, 2022
  • 752 locations
Second Uterine Evacuation for Low-risk Gestational Trophoblastic Neoplasia (ReCure)

To evaluate the efficacy and safety of second uterine curettage in patients with low-risk non-metastatic GTN.

  • 0 views
  • 04 Jun, 2022
  • 1 location
Study of Paclitaxel Plus Cisplatin as the First-line Chemotherapy in High Risk Gestational Trophoblastic Tumor

This clinical trial is designed to study the effect and safety of paclitaxel plus cisplatin as the first-line regimen in the treatment of high risk gestational trophoblastic tumor.

dactinomycin
methotrexate
total bilirubin
cyclophosphamide
trophoblastic tumor
  • 13 views
  • 15 Jun, 2022
  • 1 location
Study of Hysteroscopic Repeat Curettage as the First-line Treatment in Low-risk Postmolar Gestational Trophoblastic Neoplasia

Study of hysteroscopic repeat curettage as the first-line treatment in low-risk postmolar gestational trophoblastic neoplasia compared with the MTX single drug chemotherapy

serum bilirubin
total bilirubin
trophoblastic disease
methotrexate
  • 29 views
  • 27 Jul, 2022
  • 1 location
Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic Neoplasia

gestational trophoblastic neoplasia. It is not yet known whether multi-day methotrexate protocol is as effective as biweekly single-dose actinomycin D protocol in treating patients with gestational

serum bilirubin
gonadotropin
  • 0 views
  • 24 Nov, 2021
  • 1 location
Study of Different Therapeutic Strategies in Hydatidiform Mole With Lung Nodule

The purpose of present study is to provide clinical evidences for the appropriate management of molar pregnancy with lung nodule. The hydatidiform mole patients with lung nodule 1.0cm will be randomized into 2 groups: A. treated with chemotherapy immediately, B. follow up until hCG level met FIGO diagnostic criteria of …

hydatidiform mole
  • 42 views
  • 04 Feb, 2022
  • 1 location
Combination of Methotrexate(MTX) and Actinomycin(ACTD) in the Low Risk Gestational Trophoblastic Neoplasma GTN Patients With Score of 5-6

In this study, a prospective, multicenter randomized controlled study was conducted to compare the clinical efficacy and toxicity response of combination MTX+ACTD multi-course regimen in low-risk GTN patients with score 5-6 with standard MTX single-drug multi-course regimen.

  • 0 views
  • 23 Jan, 2021
  • 1 location