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Found 464 clinical trials
Effects of Arousal and Stress in Anxiety

This study has several parts. One part will examine the influence of factors such as personality and past experience on reactions to unpleasant stimuli. Others will examine the effect of personality and emotional and attentional states on learning and memory. When confronted with fearful or unpleasant events, people can develop …

Accepts healthy volunteers
  • 763 views
  • 22 Jan, 2022
  • 1 location
A Phase 2 Study of NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma

The purpose of this phase 2 study is to evaluate the efficacy and safety of NIR178 in combination with PDR001 in multiple solid tumors and diffuse large B-cell lymphoma (DLBCL) and further explore schedule variations of NIR178 to optimize immune activation through inhibition of A2aR.

irinotecan
tyrosine
mek inhibitor
fluoropyrimidine
melanoma skin
  • 235 views
  • 16 Jan, 2022
  • 20 locations
A Safety Study of SEA-TGT (SGN-TGT) in Advanced Cancer

This trial will look at a drug called SEA-TGT (also known as SGN-TGT) to find out whether it is safe for patients with solid tumors and lymphomas. It will study SEA-TGT to find out what its side effects are. A side effect is anything the drug does besides treating cancer. …

systemic therapy
HER2
carcinoma
hodgkin's disease
lymphoma
  • 2 views
  • 20 Dec, 2021
  • 27 locations
Safety and Efficacy of KY1044 and Atezolizumab in Advanced Cancer

A Phase 1/2, open label, multi-center study to evaluate the safety, efficacy and tolerability of KY1044 as single agent and in combination with anti-PD-L1 (atezolizumab) in adult patients with selected advanced malignancies, who are ineligible for or there are no available therapies known to confer a clinical benefit for their …

cancer
triple negative breast cancer
lung cancer
programmed cell death 1 ligand 1
breast cancer
  • 99 views
  • 13 Dec, 2021
  • 10 locations
New Heart Imaging Techniques to Evaluate Possible Heart Disease

Background Imaging tests, such as magnetic resonance imaging (MRI), can provide information about heart and blood vessels. The tests let doctors can see the amount of blood vessel narrowing and vessel wall thickness. This information may help diagnose and treat heart disease and other conditions that lead to heart attacks. …

angiography
blood test
hypertension
heart disease
diabetes mellitus
  • 193 views
  • 21 Jan, 2022
  • 1 location
Vaccination of Triple Negative Breast Cancer Patients

or III triple negative breast cancer (TNBC). This study will compare the vaccine plus standard neoadjuvant chemotherapy and surgery to standard neoadjuvant chemotherapy and surgery alone.

cancer
paclitaxel
triple negative breast cancer
breast cancer
erbb2
  • 17 views
  • 08 Aug, 2021
  • 2 locations
Radiation Immunotherapy and PARP Inhibitor in Triple Negative Breast Cancer

This research study is looking to see whether the combination of Dostarlimab and Niraparib plus Radiation Therapy (RT) is safe and effective in participants with metastatic triple negative

HER2
mammogram
triple negative breast cancer
erbb2
  • 0 views
  • 12 Sep, 2021
  • 4 locations
Neoadjuvant Camrelizumab Plus Chemotherapy in Triple Negative Breast Cancer

negative breast cancer (TNBC).

mammogram
cyclophosphamide
doxorubicin
triple negative breast cancer
docetaxel
  • 0 views
  • 28 Oct, 2021
  • 1 location
LY3023414 and Prexasertib in Metastatic Triple-negative Breast Cancer

This study evaluates efficacy of LY3023414 and prexasertib in patients with metastatic triple negative breast cancer.

cancer
triple negative breast cancer
neutrophil count
platelet count
breast cancer
  • 6 views
  • 15 Oct, 2021
  • 2 locations
Huaier Granule in Treating Women With Triple Negative Breast Cancer

Huaier Granule in treating women who have triple negative breast cancer that has been surgically removed.

cancer
platelet count
breast cancer
neutrophil count
  • 1 views
  • 21 Jan, 2021
  • 1 location