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Found 506 clinical trials
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GEN1029 (HexaBody -DR5/DR5) Safety Trial in Patients With Malignant Solid Tumors

The purpose of the trial is to evaluate the safety of GEN1029 (HexaBody-DR5/DR5) in a mixed population of patients with specified solid tumors

renal function test
metastasis
kidney function test
solid tumour
cancer
  • 218 views
  • 24 Jul, 2021
  • 6 locations
None
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

The purpose of this study is to further advance the ability to practice personalized medicine by learning which new drug agents are most effective with which types of breast cancer tumors and by learning more about which early indicators of response (tumor analysis prior to surgery via magnetic resonance imaging …

pertuzumab
MRI
doxorubicin
core needle biopsy
cyclophosphamide
  • 83 views
  • 04 Sep, 2021
  • 30 locations
None
Safety and Efficacy of Midline and PICC

The purpose of this study is to assess the non-inferiority for safety and efficacy of using Midline in comparison with PICC for intravenous therapy that do not require a central catheter.

  • 0 views
  • 31 Aug, 2021
  • 2 locations
None
Motor Language Learning

This project pursues the validation of an innovative strategy to boost language learning, based on the benefits derived from sensorimotor training. The common belief of a rigid brain structure in adult life had to be reconsidered during the last decade. After training, local increase in cerebral cortex volume and thickness, …

  • 118 views
  • 23 Jan, 2021
  • 1 location
None
Safety of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers

The primary objective of this study is to describe the safety profile of MenACYW conjugate vaccine and MENVEO when administered concomitantly with routine pediatric vaccines in healthy infants and toddlers

Accepts healthy volunteers
  • 944 views
  • 06 Dec, 2021
  • 145 locations
None
Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers

The primary objective of this study is to demonstrate the non-inferiority of the vaccine seroresponse to meningococcal serogroups A, C, Y, and W following administration of 2 doses of MenACYW conjugate vaccine compared to 2 doses of MENVEO when given concomitantly with routine pediatric vaccines to infants and toddlers 6 …

Accepts healthy volunteers
  • 420 views
  • 29 Oct, 2021
  • 110 locations
None
Combined Breast MRI and Biomarker Strategies in Identifying High-risk Breast Cancer Patients

This clinical trial studies normal breast tissue changes combined with breast magnetic resonance imaging (MRI) that may suggest the beginnings of cancer development. Using breast tissue markers in combination with breast imaging such as MRI may help to more accurately assess a woman's risk of developing breast cancer.

Accepts healthy volunteers
cancer
  • 345 views
  • 03 Dec, 2021
  • 5 locations
None
Safety and Immunogenicity of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the Russian Federation and Mexico

Primary Objective: To describe the antibody titers to the antigens (meningococcal serogroups A, C, Y, and present in MenACYW conjugate vaccine or Menveo measured by serum bactericidal assay using human complement (hSBA), for Groups 1 and 2 when administered concomitantly with routine pediatric vaccines in healthy infants and toddlers in …

Accepts healthy volunteers
  • 7 views
  • 09 Nov, 2021
  • 22 locations
None
HPV Vaccine Intervention for Young Sexual Minority Men

This phase III trial studies how well the Outsmart HPV intervention works in increasing HPV vaccine initiation and completion among young individuals who report having a history of same-sex partners, being sexually attracted to males, or identify as gay, bisexual, or queer (i.e., sexual minority males). The Outsmart HPV intervention, …

  • 0 views
  • 26 Jan, 2021
  • 2 locations
None
Sociocultural & Biobehavioral Influences on Pain Expression and Assessment

Background People can feel different levels of pain. This may depend on social, cultural, and biological factors. These factors can also influence how people respond to each other, and how they judge other people s experiences. Researchers want to learn more about these relationships. Objective To study if social and …

heat
Accepts healthy volunteers
pain assessment
  • 80 views
  • 07 Oct, 2021
  • 1 location