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Found 508 clinical trials
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The Influence of CYP2C19 Polymorphisms on the Safety and Efficacy of Voriconazole

Voriconazole is a drug used to treat invasive fungal infections. The amount of voriconazole in a person's blood helps to determine how effectively it treats an infection, and how safe it is. Patients respond differently when receiving the same dose - some clearly benefit, other patients experience side effects, and …

  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Evaluation of a Rapid Microscopic Diagnostic System for Different Vaginitis Conditions

Evaluate the diagnostic performance of the Gyni device to detect different vaginitis conditions by comparison to microscopic diagnosis and related lab tests.

  • 2 views
  • 07 Mar, 2021
  • 1 location
None
Drug-Induced Liver Injury (DILN)Network Retrospective

The purpose of this study is to establish retrospectively a nationwide registry of patients who have suffered drug-induced liver injury (DILI), and to collect, immortalize and store serum, DNA, and lymphocytes from these patients. ILIAD will serve as a resource for subsequent mechanistic investigations into the basis of severe idiosyncratic …

  • 228 views
  • 14 Feb, 2021
  • 7 locations
None
Estimating Brain Biomechanics Using MRI

Objective: In this study we will develop and apply imaging techniques to perform the first three-dimensional (3-D) measurements of brain biomechanics during mild head movement in healthy human subjects. Biomechanics is the application of mechanics, or the physical principles in action when force is applied to an object, to the …

Accepts healthy volunteers
imaging techniques
head up
  • 78 views
  • 07 Nov, 2021
  • 1 location
None
Links Between Inflammation and Cardiometabolic Diseases

Background Cardiometabolic diseases are a combination of medical disorders that, when they occur together, increase the risk of heart disease and diabetes. Researchers want to learn if there is a relationship between these diseases and inflammation (redness, swelling, and pain). Inflammation affects the entire body. Researchers will study this relationship …

diabetes
electrocardiogram
fats
angina pectoris
edema
  • 19 views
  • 26 Nov, 2021
  • 1 location
None
TDM for Optimized Outcome in Patients With mRCC.

The purpose of this observational study is to assess the role of plasma concentration monitoring of treatment drugs for patients with metastatic renal cell carcinoma (mRCC) in terms of efficacy and side effects. Furthermore, the investigators intend to evaluate the role of anti-drug antibodies, amount of bound drug to T …

  • 0 views
  • 27 Jan, 2021
  • 3 locations
None
TRACERx Renal CAPTURE Sub-study

TRACERx Renal: This is a translational study, which, aims to develop prognostic and predictive biomarkers for patients with renal cell carcinoma (RCC). CAPTURE Sub-study: Covid-19 antiviral response in a pan-tumour immune monitoring study

carcinoma
cancer
nephrectomy
metastasectomy
primary cancer
  • 13 views
  • 24 Jan, 2021
  • 4 locations
None
Collection of Immunology Specimens From Patients With Cancer or Blood Disorders and Healthy Volunteers

This research trial collects and stores blood, tissue, and bone marrow specimens from patients with cancer or blood disorders, and healthy volunteers to study the immune system in a variety of different types of experiments, as well as associated clinical data as appropriate, focused on understanding mechanisms of immunotherapy.

diabetes
immunosuppressive agents
primary cancer
immunosuppressive
immunosuppressant
  • 254 views
  • 12 Apr, 2021
  • 1 location