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Found 458 clinical trials
Links Between Inflammation and Cardiometabolic Diseases

Background Cardiometabolic diseases are a combination of medical disorders that, when they occur together, increase the risk of heart disease and diabetes. Researchers want to learn if there is a relationship between these diseases and inflammation (redness, swelling, and pain). Inflammation affects the entire body. Researchers will study this relationship …

heart disease
angina pectoris
Accepts healthy volunteers
  • 27 Jul, 2022
  • 1 location
SPRINT: Signature for Pain Recovery IN Teens (SPRINT)

To identify biological and phenotypic prognostic markers of recovery vs. persistence of pain and functional disability in adolescents with chronic musculoskeletal pain.

pain visual analogue scale
chronic pain
Accepts healthy volunteers
amplified musculoskeletal pain syndrome
  • 06 May, 2022
  • 3 locations
Myeloid Derived Suppressor Cells Clinical Assay in Finding Kidney Cancer

This pilot research trial studies the use of the Myeloid Derived Suppressor Cells Clinical Assay in finding and monitoring kidney cancer. Studying samples of blood and urine from patients with kidney cancer in the laboratory may aid doctors in the early detection of cancer, monitor tumor response to therapy, detect …

metastatic renal cell carcinoma
neutrophil count
Accepts healthy volunteers
  • 25 Nov, 2021
  • 1 location
4D-MRI for Precision Medicine

The purpose of this study is to develop new ways to make medical images of the lungs and liver of adults using a technique called four-dimensional magnetic resonance imaging (4D-MRI). This technique produces three-dimensional movies of the inside of the chest and abdomen while the patient is breathing. (The fourth …

  • 28 Jan, 2021
  • 1 location
TRACERx Renal CAPTURE Sub-study

TRACERx Renal: This is a translational study, which, aims to develop prognostic and predictive biomarkers for patients with renal cell carcinoma (RCC). CAPTURE Sub-study: Covid-19 antiviral response in a pan-tumour immune monitoring study

primary cancer
cancer diagnosis
  • 24 Jan, 2021
  • 4 locations
TDM for Optimized Outcome in Patients With mRCC.

The purpose of this observational study is to assess the role of plasma concentration monitoring of treatment drugs for patients with metastatic renal cell carcinoma (mRCC) in terms of efficacy and side effects. Furthermore, the investigators intend to evaluate the role of anti-drug antibodies, amount of bound drug to T …

  • 27 Jan, 2021
  • 3 locations
Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers

This research trial collects and stores blood, tissue, and bone marrow specimens from patients with cancer or blood disorders, and healthy volunteers to study the immune system in a variety of different types of experiments, as well as associated clinical data as appropriate, focused on understanding mechanisms of immunotherapy.

hematologic disorders
cardiovascular disease
systemic lupus erythematosus
immunosuppressive agents
Accepts healthy volunteers
  • 24 Feb, 2022
  • 1 location
TAD in Primary Breast Cancer With Initially ≥ 3 Suspicious Lymph Nodes (SenTa 2)

Due to high pathological complete remission (pCR) rates in both breast and lymph nodes (ypT0/Tis, ypN0) following neoadjuvant systemic therapy (NST) in many patients with initially clinically node-positive (cN+) breast cancer, the standard treatment of the axilla has changed from axillary lymph node dissection (ALND), which is associated with high …

core needle biopsy
invasive breast cancer
axillary lymph node dissection
  • 25 Jul, 2022
  • 1 location