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Found 458 clinical trials
Eribulin as a Second-line Treatment in Triple-negative Advanced Breast Cancer (HERMIONE-10)

Multicenter, retrospective and prospective, cohort, observational study evaluating the clinical efficacy and tolerability of Eribulin as second-line treatment in accordance with the indications authorized by AIFA in patients with triple negative advanced breast cancer in a real world setting.

HER2
anthracyclines
erbb2
advanced breast cancer
  • 0 views
  • 20 Apr, 2022
  • 1 location
Study of Screening Brain MRIs in Stage IV Breast Cancer

The study is a single arm, nonrandomized phase II prospective study, with the goal of investigating the role of screening brain MRIs in neurologically asymptomatic patients with metastatic breast cancer.

erbb2
stage iv breast cancer
HER2
  • 0 views
  • 06 May, 2022
  • 1 location
Breast Cancer BRCA1 Carriers: a Pilot Study

The purpose of this study is to examine how a single dose of MIFEPREX® (mifepristone) affects the breast tissue in patients with BRCA1 (a gene that normally acts to restrain the growth of cells in the breast, but if it mutates may lead to breast cancer) mutations undergoing a planned …

  • 0 views
  • 15 Jun, 2022
  • 2 locations
Assessment of Complete Pathologic Response After Neoadjuvant Chemotherapy for Breast Cancer

This is a feasibility study to gain preliminary information regarding whether breast imaging with or without a core needle biopsy after neoadjuvant chemotherapy (NAC) but before surgery can accurately predict complete pathologic response (pCR) in women with triple negative or HER2- positive breast cancer. pCR is defined as having no …

core needle biopsy
cancer
invasive breast cancer
carcinoma
erbb2
  • 0 views
  • 15 Feb, 2022
  • 1 location
Personalized Patient Derived Xenograft (pPDX) Modeling to Test Drug Response in Matching Host (REFLECT)

By obtaining clinical specimens from participants with triple negative breast cancer (TNBC), colorectal cancer (CRC), high grade serous ovarian cancer (HGSOC), and other select tumor types to

cancer
cancer treatment
cancer chemotherapy
residual tumor
cancer of the ovary
  • 0 views
  • 30 Apr, 2022
  • 1 location
Role of the Immune Environment in Response to Therapy in Breast Cancer

This is an observational case-control study of tissues collected from women with ER+HER2- breast cancers. The immune environments of these cancers will be compared to triple negative and HER2+ breast cancers. No randomization or changes to standard of care treatment will occur as part of the study.

erbb2
HER2
  • 0 views
  • 15 Jun, 2022
  • 1 location
Bringing of PET-TDM FDG in the Determination of the Characteristics of Primary Mammary Tumors TrIple Negatives (FICTION)

and texture) in a population of Triple Negative Breast Cancer scans better knowledge of this entity that can lead to the development of relevant therapeutic strategies and especially more adapted in

estrogen
progesterone
immunohistochemistry
metastasis
erbb2
  • 0 views
  • 24 Feb, 2022
  • 1 location
Targeted Axillary Dissection After Neo-adjuvant Chemotherapy

patients, however, the investigators see a nodal complete pathological response (ypN0). In certain subgroups, triple negative breast cancer and Her2 amplified breast cancer, this percentage is even higher

HER2
adjuvant chemotherapy
axillary lymph node dissection
sentinel node
triple negative breast cancer
  • 0 views
  • 18 Dec, 2021
  • 1 location
Relationship Between Breast Cancer Subtypes and Immune Checkpoints

study is to determine the relationship between Luminal A, Luminal B and triple negative breast cancer and soluble immune control points, and to guide possible potential immunotherapy treatments.

ki-67
tumor cells
triple negative breast cancer
erbb2
HER2
  • 0 views
  • 21 Jul, 2022
  • 2 locations
Prospective Evaluation of Next Generation CT Reconstruction (NextGenIR)

Background Computed Tomography (CT) is a scan that makes detailed pictures of the body. It uses radiation to do that. In 2011, about 85.3 million CT scans were done in the United States. But there is growing concern about the health effects of radiation. There are new and different ways …

  • 5 views
  • 27 Jul, 2022
  • 1 location