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Found 458 clinical trials
LobularCard Trial: Searching for Novel Germline Mutations in Lobular Breast Cancer Patients (LobularCard)

This is a cross-sectional and retrospective study of a cohort of patients with invasive lobular breast cancer (LBC) or in situ lobular neoplasia (LIN3). The main endpoint is the relative frequency of patients with a germline mutation using a recent panel including 113 genes from the "Illumina" protocol. In case …

  • 0 views
  • 15 Jun, 2022
  • 1 location
Tumor-Infiltrating Lymphocytes and Programmed Cell Death - Ligand 1 in Breast Cancer

The morphological evaluation of Tumor-infiltrating Lymphocytes (TILs) in breast cancer is gaining momentum as evidence strengthens for the clinical relevance of this immunological biomarker. In breast cancer (BC) lesions, TILs are seen in intratumoral and stromal areas. TILs are predictive of response to treatment and this association appears to be …

estrogen receptor
epidermal growth factor receptor
metastasis
immunohistochemistry
estrogen
  • 0 views
  • 11 Mar, 2022
  • 1 location
Construction and Validation of an Assessment Model of PCR After NAT on Breast Cancer Patients With AI Technology

Breast cancer is a major cause of survival for women worldwide. Neoadjuvant therapy as an important treatment for locally advanced breast cancer has had many positive effects for breast cancer patients. As drug therapy for breast cancer continues to evolve, the percentage of pathologic complete responses continues to increase. However, …

invasive breast cancer
locally advanced breast cancer
advanced breast cancer
  • 0 views
  • 14 Jul, 2022
  • 1 location
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases. This program allows patients and researchers to connect as easily as possible to help advance treatments and cures …

other disease
rare diseases
  • 4 views
  • 15 Jul, 2022
  • 2 locations
Evaluation of Prognostic Monitoring for Triple Negative Breast Cancer Patients

The relationship between immune inflammation-related protein complexes in blood of triple negative breast cancer patients and recurrence or metastasis of breast cancer will be studied.

invasive breast cancer
cancer
breast cancer
triple negative breast cancer
metastasis
  • 2 views
  • 15 Feb, 2022
  • 1 location
Molecular Profiling After Neoadjuvant Chemotherapy for Triple-negative Breast Cancer

Neoadjuvant chemotherapy (NACT) can induce complete pathologic response (pCR) in approximately 35-55% of patient with triple-negative breast cancer (TNBC). These patients have excellent long

invasive breast cancer
mastectomy
adjuvant chemotherapy
lumpectomy
HER2
  • 0 views
  • 05 Mar, 2022
  • 1 location
Image-based AI Predictive Biomarkers for Precision Neoadjuvant Triple-negative Breast Cancer Treatment (PEAR-TNBC)

Pear Bio has developed an organ-on-a-chip device together with a computer vision pipeline through which the response of an individual patient's tumor to different chemotherapy regimens can be tested simultaneously ex vivo. This study will recruit patients with early TNBC who are planned for standard of care neoadjuvant chemotherapy followed …

core needle biopsy
  • 0 views
  • 07 Jul, 2022
  • 1 location
Correlation Between TILs and Blood Cell Counts in Triple Negative Breast Cancer Patients (PERCEPTION)

-Lymphocyte Ratio)) and Tumor Infiltrating Lymphocytes (TILs), at baseline and after surgery, for patients diagnosed with triple negative breast cancer. It also aims to assess these circulating elements and

Accepts healthy volunteers
neutrophil count
breast cancer
triple negative breast cancer
cancer
  • 1 views
  • 27 Jun, 2022
  • 1 location
Next-Generation Sequencing-based Germline and Somatic Genetic Testing in Triple-negative Breast Cancer (PERSONA)

For patients with triple negative breast cancer, implementation of genetic testing in decision making might impact both risk management for the patient and her family, but also, importantly

mastectomy
estrogen receptor
triple negative breast cancer
epidermal growth factor receptor
estrogen
  • 0 views
  • 03 Feb, 2022
  • 1 location
Gut and Intratumoral Microbiome Effect on the Neoadjuvant Chemotherapy-induced Immunosurveillance in Triple Negative Breast Cancer

The probability of pCR in TNBC patients receiving standard of care neoadjuvant chemotherapy treatment is associated with the dominance of specific intestinal and intratumoral microbiota that promote anti-tumor immunosurveillance.

HER2
cancer
erbb2
breast cancer
triple negative breast cancer
  • 9 views
  • 09 Apr, 2022
  • 3 locations