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Found 479 clinical trials
Preoperative Lenvatinib Plus Pembrolizumab in Early-Stage Triple-Negative Breast Cancer (TNBC)

This is a single arm, window of opportunity study in which participants with previously untreated triple negative breast cancers (TNBC) who are candidates for potentially curative surgery will receive one 21-day cycle of therapy prior to surgery, consisting of lenvatinib 12 mg daily, days 1 through 14, and pembrolizumab 200 …

excisional biopsy
lumpectomy
breast cancer
epidermal growth factor
HER2
  • 0 views
  • 10 Jun, 2021
  • 1 location
Neoadjuvant Treatment of Early Triple-negative Breast Cancer With Chidamide and Chemotherapy

safety of chemotherapy with Chidamide and chemotherapy alone in the neoadjuvant treatment of stage II - III triple-negative breast cancer

epirubicin
HER2
docetaxel
erbb2
  • 0 views
  • 27 Jan, 2021
  • 1 location
Cabiralizumab in Combination With Nivolumab and Neoadjuvant Chemotherapy in Patients With Localized Triple-negative Breast Cancer

infiltrating lymphocytes (TIL) compared to neoadjuvant chemotherapy plus nivolumab in patients with early stage triple-negative breast cancer (TNBC) and improve clinical outcomes.

growth factor
erbb2
HER2
paclitaxel
carboplatin
  • 0 views
  • 18 Apr, 2022
  • 1 location
Ipatasertib Plus Non-Taxane Chemotherapy for Advanced or Metastatic Triple-Negative Breast Cancer (PATHFINDER)

locally advanced or metastatic triple-negative breast cancer patients

taxane
capecitabine
carboplatin
  • 0 views
  • 24 Apr, 2022
  • 12 locations
The TP Regimen in the Treatment of Early Triple Negative Breast Cancer

Previous studies have shown that TNBC is sensitive to DNA crosslinking-related chemotherapeutic drugs such as platinum. However, there is a lack of large sample prospective clinical data to compare the efficacy of TP and EC-T / TEC regimen in the neoadjuvant chemotherapy of TNBC. Besides, the application of anthracycline drugs …

doxorubicin
erbb2
adriamycin
mammogram
docetaxel
  • 0 views
  • 06 Dec, 2021
  • 1 location
  • 0 views
  • 26 Jan, 2021
  • 1 location
PAveMenT: Palbociclib and Avelumab in Metastatic AR+ Triple Negative Breast Cancer

This clinical study is aiming to determine the safest doses and schedule for the combination of two drugs named palbociclib and avelumab. The study will also be investigating how effective the combination is for a subgroup of breast cancer patients whose cancer expresses the androgen receptor (AR) but not the …

breast cancer
her2/neu-positive breast cancer
HER2
cancer treatment
hysterectomy
  • 1 views
  • 30 May, 2021
  • 1 location
INCMGA00012 and Pelareorep for the Treatment of Metastatic Triple Negative Breast Cancer, IRENE Study

This is a phase 2 study to evaluate the safety and efficacy of the combination of INCMGA00012 and pelareorep and to see how well they work in treating patients with triple negative breast cancer

anticoagulants
breast cancer
epidermal growth factor
HER2
programmed cell death 1 ligand 1
  • 0 views
  • 05 May, 2022
  • 2 locations
Imaging Performance Assessment of 89Zirconium-labelled Girentuximab (89Zr-TLX250) PET-CT in Metastatic Triple Negative Breast Cancer Patients

negative breast cancer (TNBC) patients.

erbb2
estrogen
epidermal growth factor
HER2
epidermal growth factor receptor
  • 0 views
  • 28 Oct, 2021
  • 1 location
CMP-001 and Pre-operative Stereotactic Body Radiation Therapy (SBRT) in Early Stage Triple Negative Breast Cancer (TNBC)

This is an open-label, randomized, window-of-opportunity phase 2 clinical study evaluating the biological activity of preoperative Stereotactic Body RadioTherapy (SBRT) alone (Arm 1), and combined with subcutaneous (SC) followed by intra-tumoral (IT) administrations of CMP-001 (Arm 2), in subjects with early stage TNBC. Safety and efficacy of the treatments are …

epidermal growth factor
HER2
mammogram
epidermal growth factor receptor
EGFR
  • 0 views
  • 19 Jul, 2021
  • 1 location