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Found 570 clinical trials
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A Phase 1, Open-Label, Dose-Escalation, Safety and Tolerability Study of INCAGN02390 in Participants With Select Advanced Malignancies

The purpose of this study is to determine the safety, tolerability, and preliminary efficacy of INCAGN02390 in participants with advanced malignancies. This investigational intervention treatment uses a single biological drug and is conducted in two parts. Part 1: INCAGN02390 at the protocol-defined starting dose administered every 2 weeks (Q2W), with …

cancer
advanced cancer
  • 128 views
  • 14 Dec, 2020
  • 4 locations
Carboplatin in EARLY Triple Negative Breast Cancer Trial (PEARLY Trial)

patients with triple-negative breast cancer. Patients with stage II/III operable triple-negative breast cancer are eligible. Patients who need adjuvant chemotherapy after breast surgery as well as

invasive carcinoma
doxorubicin
invasive breast cancer
primary tumor
paclitaxel
  • 82 views
  • 08 Nov, 2020
  • 10 locations
Adjuvant Endocrine Therapy for Estrogen Receptor-beta Positive Triple Negative Breast Cancer

endocrine therapy for operable ER-beta positive, ER-alpha/PR negative, Her-2 negative breast cancer(triple negative breast cancer, TNBC) patients. The ER-beta positive TNBC patients who had undergone

hormone therapy
mastectomy
estrogen receptor
breast-conserving surgery
endocrine therapy
  • 7 views
  • 08 Nov, 2020
Adjuvant Treatment of EC Followed by Taxane +/- Carboplatin in Triple-Negative Breast Cancer

(EC-TCb) in triple-negative breast cancer.

epirubicin
paclitaxel
cyclophosphamide
carcinoma
docetaxel
  • 90 views
  • 16 Apr, 2020
  • 27 locations
Study Comparing EC-T Verses PCb in the Adjuvant Chemotherapy of Non-triple Negative Breast Cancer

docetaxel (EC4-T4) verses 6 cycles of weekly paclitaxel combined with carboplatin (PCb*6) in the adjuvant chemotherapy of non-triple negative breast cancer patients. The study is divided in to 2

epidermal growth factor receptor
invasive breast cancer
cish
paclitaxel
trastuzumab
  • 2 views
  • 15 Mar, 2020
  • 1 location
Platinum and Polyadenosine 5'Diphosphoribose Polymerisation (PARP) Inhibitor for Neoadjuvant Treatment of Triple Negative Breast Cancer (TNBC) and/or Germline BRCA (gBRCA) Positive Breast Cancer

This neoadjuvant trial for patients with TNBC and/or gBRCA breast cancer, aims to investigate the safety and efficacy (improvement in pathological Complete Response at surgery) of concurrent platinum-based chemotherapy with olaparib an inhibitor of the PARP enzyme (PARPi).

invasive breast cancer
paclitaxel
EGFR
triple negative breast cancer
adjuvant therapy
  • 10 views
  • 08 Nov, 2020
  • 1 location
Neoadjuvant Carboplatin in Triple Negative Breast Cancer

Breast cancer is the most frequent neoplasm in women in Brazil and in the world and up to 15% of all cases diagnosed correspond to the triple negative subtype. Triple negative breast cancer

  • 2 views
  • 22 Jul, 2019
  • 1 location
Vaccination of Triple Negative Breast Cancer Patients

The purpose of this research is to compare the effect on breast cancer of using a new experimental breast cancer vaccine (used to stimulate immune cell production) with chemotherapy and surgery versus the usual treatment of chemotherapy and surgery.

cancer
breast cancer
triple negative breast cancer
  • 17 views
  • 10 Feb, 2020
  • 2 locations
Huaier Granule in Treating Women With Triple Negative Breast Cancer

safety of Huaier Granule in treating women who have triple negative breast cancer that has been surgically removed.

platelet count
cancer
neutrophil count
breast cancer
  • 1 views
  • 08 Nov, 2020
  • 1 location
Imipramine on ER+ve and Triple Negative Breast Cancer

Comparing changes in biomarkers from a diagnostic core needle biopsy to surgical pathology specimen or repeat core needle biopsy.

lobular carcinoma
carcinoma
core needle biopsy
triple negative breast cancer
  • 0 views
  • 17 Aug, 2020
  • 1 location