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Found 125 clinical trials
A Study to Evaluate the Long-term Safety and Tolerability of SAGE-324 in Participants With Essential Tremor

The primary purpose of this study is to evaluate the long-term safety and tolerability of SAGE-324 in participants with essential tremor (ET).

  • 1 views
  • 04 Oct, 2022
  • 1 location
Closing the Loop on Tremor: A Responsive Deep Brain Stimulator for the Treatment of Essential Tremor

Essential tremor is an incurable, degenerative brain disorder that results in increasingly debilitating tremor, and afflicts an estimated 7 million people in the US. In one study, 25% of

propranolol
nervous
fahn
limb tremor
depression
  • 46 views
  • 18 Oct, 2022
  • 1 location
Transcranial Ultrasound Therapy of Essential Tremor

Context. Essential tremor (ET) is a common disease, disabling in severe forms and resistant to drug treatment. In patients with severe ET, invasive neurosurgical technique such as deep brain

movement disorder
depression
brain stimulation
MRI
  • 345 views
  • 24 Jan, 2021
  • 1 location
Bilateral Essential Tremor Treatment With FUS (BEST-FUS)

tremor will undergo a contralateral treatment. The incidence of side effects will be determined at 1 and 3 months postoperatively, graded per the CTCAE v5 and analyzed by a data safety monitoring board

thalamotomy
movement disorder
MRI
  • 41 views
  • 26 May, 2022
  • 1 location
The Swedish Essential Tremor (SWEET) Trial (SWEET)

To evaluate the effect of deep brain stimulation (DBS) vs best medical treatment in essential tremor (ET) in a randomized, single-blinded controlled trial.

movement disorder
brain stimulation
  • 70 views
  • 05 Jun, 2022
  • 5 locations
Cyclic Deep Brain Stimulation in Essential Tremor

The aim of the study is to prove the efficacy and safety of cyclical deep brain stimulation (DBS) in patients with essential tremor, and demonstrate non-inferiority of cyclical DBS on tremor

brain stimulation
  • 87 views
  • 25 Feb, 2022
  • 1 location
Bilateral Essential Tremor Treatment With Gamma Knife

Combined Phase II/III, multi-center, prospective, single-blinded trial. Ten (10) patients with essential tremor who previously underwent successful and uncomplicated GK thalamotomy for

movement disorder
icons
thalamotomy
  • 7 views
  • 24 Nov, 2021
  • 2 locations
Optimization of VIM Targeting in Essential Tremor Surgery (Opti-VIM)

Deep brain stimulation (DBS) for essential tremor is based on the intermedius ventralis nucleus of the thalamus (VIM) stimulation. This structure is however very difficult to target, as it

brain stimulation
MRI
  • 0 views
  • 14 May, 2022
  • 2 locations
Long-Term Transcutaneous Stimulation and Essential Tremor: A PET Study

Essential tremor (ET) is the most common movement disorder in the United States and affects up to 5% of the population. ET patients experience involuntary shaking of the hands, head and/or voice

caffeine
nervous
movement disorder
hand tremor
brain stimulation
  • 106 views
  • 17 Mar, 2022
  • 1 location
A Second Magnetic Resonance Guided Focused Ultrasound Thalamotomy for Essential Tremor

This study will be a single-centre, prospective, single-arm, open-label, 12-week pilot trial assessing the safety and preliminary efficacy of a second MR-guided focused ultrasound (MRgFUS) thalamotomy on the naïve brain hemisphere after 48 weeks or more of the first MRgFUS thalamotomy in patients with medication-refractory ET. This study will be …

thalamotomy
propranolol
primidone
MRI
  • 22 views
  • 29 May, 2022
  • 1 location