Found 215 clinical trials
Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer (CHALLENGE)
RATIONALE: Participating in a physical activity program designed to increase free time physical activity and receiving written health education materials may influence the chance of cancer recurring as well as impact on physical fitness, psychological well-being and the quality of life of patients who have undergone surgery and chemotherapy for …
- 657 views
- 06 Apr, 2023
- 47 locations
Enhanced, EHR-facilitated Cancer Symptom Control Pragmatic Clinical Trial (E2C2)
This early phase I trial investigates enhanced, electronic health record (EHR)-facilitated cancer system control. Cancer and its treatment are often associated with severe, disabling symptoms that have been causally linked to diminished survival, increased healthcare utilization, degraded quality of life, unemployment, and non-adherence to recommended cancer treatments. Collaborative case management …
- 31 views
- 04 Oct, 2022
- 1 location
Outcomes Mandate National Integration With Cannabis as Medicine (OMNI-Can)
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- 15311 views
- 13 Jun, 2022
- 16 locations
A Randomized Controlled Study of Digitalized Cognitive Behavioral Intervention for Antenatal Depression
The main objective of the current research project is to evaluate the effectiveness of the digitalized cognitive behavioral therapy program including telephone coaching for antenatal depressive symptoms. The participants are screened from the general population of pregnant women, as a part of the routine maternity health care check-ups. Mothers with …
- 0 views
- 26 Aug, 2021
- 1 location
Depression Screening in Black Churches
The overall aim of this study is to employ Community Health Workers (CHWs) to screen for depression in 30 Black churches and compare the effectiveness of Screening, Brief Intervention, and Referral to Treatment (SBIRT) (Intervention arm) to Referral As Usual (Control arm) on treatment engagement for depression. The investigators will …
- 0 views
- 04 Oct, 2022
- 1 location
Ketamine Alcohol (in Treatment-Resistant Depression)
A single subanesthetic dose infusion of the N-methyl-D-aspartate (NMDA) receptor antagonist ketamine has rapid and robust antidepressant effects in patients with treatment-refractory major depressive disorder (TRD). A family history of an alcohol use disorder (Family History Positive, FHP) is one of the strongest identified predictors of an improved antidepressant response …
- 109 views
- 07 Oct, 2022
- 1 location
Targeting IL-17A for Treatment-Resistant Depression
The proposed study aims to test ixekizumab, a monoclonal antibody (mAb) against interleukin 17A (IL-17A), in patients with treatment-resistant depression (TRD).
- 0 views
- 27 Nov, 2021
- 1 location
Biomarker-guided rTMS for Treatment Resistant Depression (BioTMS)
Repetitive transcranial magnetic stimulation (rTMS) is a treatment for depression. The investigators are continuing to learn how to optimize outcomes from rTMS treatment. The purpose of this research project is to use brain network connectivity patterns as measured by resting state functional magnetic resonance imaging (fMRI) to confirm a way …
- 0 views
- 10 Jul, 2022
- 1 location
Dorsomedial Prefrontal Neuromodulation in Treatment-resistant Depression
several antidepressant trials, so-called treatment-refractory depression (TRD). The high-frequency repetitive transcranial magnetic stimulation (rTMS) or intermittent theta-burst stimulation (iTBS) at
- 0 views
- 04 Oct, 2022
- 1 location
Low-dose Ketamine Infusion Among Adolescents With Treatment-resistant Depression
optimal dose and adequate duration. Those patients would be considered the cases with treatment-resistant depression (TRD), which is related to the poor prognosis, chronic depressive course, higher
- 0 views
- 20 Apr, 2022
- 1 location