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Found 318 clinical trials
Mindfulness-based Therapy Versus Relaxation in Prevention of Burnout in Medical Students (MUSTPrevent)

A recent survey exploring mental health in a large cohort of French medical students and young graduates (N = 21.768), observed that 68.2% of participants showed pathologic anxiety. A high level of depressive symptomatology was found in 27.7% of participants, while suicidal ideation was reported by 23.7%. Mindfulness Based Interventions …

suicidal
Accepts healthy volunteers
anxiety
  • 36 views
  • 16 Feb, 2022
  • 1 location
The Efficacy of Automated Feedback After Internet-based Depression Screening (DISCOVER)

The DISCOVER randomized controlled trial is designed to evaluate the effect of automated feedback after internet-based depression screening in individuals with undetected depression. A total of 1076 individuals reporting elevated levels of depression (PHQ-9 score ≥ 10 points) will be randomized into three groups to either receive a) no feedback …

depressed mood
depression screening
  • 0 views
  • 29 May, 2022
  • 1 location
Follow-up Study With Clinical Vitamin D Supplementation Trial on Patients With Depression (DepFuD)

Depression affects 350 million people worldwide. In the light of the global disease burden statistics, the efficacy of current treatments for depression appears insufficient. Thus, research on novel treatment interventions and predictors for good treatment response are warranted. Earlier prospective follow-up studies and intervention studies suggest that several bio-psychosocial factors, …

major depressive disorder
severe depression
scid
depressed mood
recurrent depression
  • 4 views
  • 23 Jan, 2021
  • 1 location
Health cAre woRkers exposeD to COVID-19 (HARD-COVID19)

Health care workers working in hospital or nursing home for elderly people involved in the coronavirus epidemic are facing several challenges such as direct exposure and involvement in the resolution of major public health emergencies, exposure to potentially fatal contamination, physical exhaustion, unadjusted work organizations, the unusual number of deaths …

covid-19
psychological distress
depressed mood
depression
  • 0 views
  • 07 Mar, 2022
  • 2 locations
A Depression and Opioid Pragmatic Trial in Pharmacogenetics (DCRI Coordinating Center) (ADOPT PGx)

This study is comprised of three separate pharmacogenetic trials grouped into a single protocol due to similarities in the intervention, the hypotheses, and the trial design. The three trials are the Acute Pain Trial, the Chronic Pain Trial, and the Depression Trial. Participants can enroll in only one of the …

selective serotonin reuptake inhibitors
hydrocodone
opioid
codeine
depressed mood
  • 263 views
  • 11 Jul, 2022
  • 10 locations
Clinical Trial of Fluoxetine in Anxiety and Depression in Children, and Associated Brain Changes

Objective: This protocol uses functional magnetic resonance imaging (fMRI) to examine neuro-cognitive correlates of pediatric and adult mood and anxiety disorders. The primary goal of the project is to document, in pediatric anxiety disorders and major depression, perturbations in brain systems mediating attention biases, fear conditioning, emotional memory, and response …

behavior therapy
major depressive disorder
depressed mood
MRI
depression
  • 721 views
  • 21 Jul, 2022
  • 1 location
Integrated Mental Health Care and Vocational Rehabilitation to People With to Common Mental Disorders

The purpose of this study is to investigate the efficacy of an integrated mental health care and vocational rehabilitation intervention for people on sick leave because of depression, stress, anxiety, personality- and functional disorders in Denmark

depressed mood
depression
psychiatric disorder
anxiety
  • 0 views
  • 16 Sep, 2021
  • 1 location
POST Facilitation for Community Dwelling Older Adults (POST-RCT) (POST-RCT)

We propose to study the effects of Physician Orders for Scope of Treatment (POST) Facilitation in a randomized controlled trial in a population of community dwelling older adults who qualify for POLST facilitation, including those with normal cognition and those with Alzheimer's Disease and Related Disorders.

cancer
  • 151 views
  • 02 May, 2022
  • 2 locations
Our Family Our Future: A Resilience-oriented Family Intervention to Prevent Adolescent HIV/STI Infection and Depression in South Africa

The purpose of this study is to test the efficacy of Our Family Our Future, an integrated intervention for preventing HIV and depression onset among adolescents.

depressive disorder
HIV Vaccine
depressive symptoms
depressed mood
depression
  • 207 views
  • 03 Jun, 2021
  • 1 location
Rural Dementia Caregiver Project

These caregivers are a vulnerable group due to their physical isolation and well-documented rural disparities in health care access and quality. Many rural dementia caregivers experience serious health consequences due to caregiving responsibilities that can limit their ability to maintain their caregiving role. Thus, there is a pressing need for …

alzheimer's disease
Accepts healthy volunteers
depressive symptoms
depressed mood
depression
  • 0 views
  • 26 Jan, 2022
  • 1 location