Found 217 clinical trials
PATH 2 Purpose: Primary Care and Community-Based Prevention of Mental Disorders in Adolescents (P2P)
PATH (Promoting AdolescenT Health) 2 Purpose is a two-arm comparative effectiveness research trial to that will evaluate the ability of the interventions, Competent Adulthood Transition with Cognitive-behavioral & Interpersonal Training (CATCH-IT) and Teens Achieving Mastery over Stress (TEAMS), to intervene early to prevent depressive illness and potentially other common mental …
- 47 views
- 04 Oct, 2022
- 1 location
Music Interventions for Dementia and Depression in Elderly Care (MIDDEL)
This study evaluates the effectiveness of two music-based approaches - group music therapy and recreational choir singing - for reducing depression symptoms in people living with dementia. It also examines mechanisms and heterogeneity of treatment effects.
- 31 views
- 22 Mar, 2022
- 5 locations
3D Team Care for Cognitively Vulnerable Older Adults
This study addresses how to achieve better outcomes for cognitively vulnerable community-dwelling older adults and their families. Cognitive vulnerability means living with dementia, depression, and/or a recent episode of delirium (the 3Ds). The investigators will test the effectiveness of a team care model focused on the 3Ds (Home Based Care …
- 34 views
- 08 Apr, 2023
- 1 location
Mindfulness-based Therapy Versus Relaxation in Prevention of Burnout in Medical Students (MUSTPrevent)
A recent survey exploring mental health in a large cohort of French medical students and young graduates (N = 21.768), observed that 68.2% of participants showed pathologic anxiety. A high level of depressive symptomatology was found in 27.7% of participants, while suicidal ideation was reported by 23.7%. Mindfulness Based Interventions …
- 36 views
- 16 Feb, 2022
- 1 location
Follow-up Study With Clinical Vitamin D Supplementation Trial on Patients With Depression (DepFuD)
Depression affects 350 million people worldwide. In the light of the global disease burden statistics, the efficacy of current treatments for depression appears insufficient. Thus, research on novel treatment interventions and predictors for good treatment response are warranted. Earlier prospective follow-up studies and intervention studies suggest that several bio-psychosocial factors, …
- 4 views
- 23 Jan, 2021
- 1 location
Collaboration Leading to Addiction Treatment and Recovery From Other Stresses (CLARO)
Collaboration Leading to Addiction Treatment and Recovery from Other Stresses (CLARO) is a five-year project that tests whether delivering care using a collaborative model helps patients with both opioid use disorders and mental health disorders.
- 37 views
- 07 Oct, 2022
- 3 locations
A Depression and Opioid Pragmatic Trial in Pharmacogenetics (DCRI Coordinating Center) (ADOPT PGx)
This study is comprised of three separate pharmacogenetic trials grouped into a single protocol due to similarities in the intervention, the hypotheses, and the trial design. The three trials are the Acute Pain Trial, the Chronic Pain Trial, and the Depression Trial. Participants can enroll in only one of the …
- 299 views
- 04 Oct, 2022
- 10 locations
Clinical Trial of Fluoxetine in Anxiety and Depression in Children, and Associated Brain Changes
Objective: This protocol uses functional magnetic resonance imaging (fMRI) to examine neuro-cognitive correlates of pediatric and adult mood and anxiety disorders. The primary goal of the project is to document, in pediatric anxiety disorders and major depression, perturbations in brain systems mediating attention biases, fear conditioning, emotional memory, and response …
- 761 views
- 04 Apr, 2023
- 1 location
POST Facilitation for Community Dwelling Older Adults (POST-RCT) (POST-RCT)
We propose to study the effects of Physician Orders for Scope of Treatment (POST) Facilitation in a randomized controlled trial in a population of community dwelling older adults who qualify for POLST facilitation, including those with normal cognition and those with Alzheimer's Disease and Related Disorders.
- 151 views
- 02 May, 2022
- 2 locations
Our Family Our Future: A Resilience-oriented Family Intervention to Prevent Adolescent HIV/STI Infection and Depression in South Africa
The purpose of this study is to test the efficacy of Our Family Our Future, an integrated intervention for preventing HIV and depression onset among adolescents.
- 207 views
- 03 Jun, 2021
- 1 location