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Found 284 clinical trials
Hyperbaric Oxygen Treatment of Mandibular Osteoradionecrosis. A Randomized Clinical Study

There is currently not sufficient evidence that hyperbaric oxygen (HBO) benefits the surgical removal of necrotic bone in osteoradionecrosis patients. This study aims at testing the hypothesis that HBO does improve healing after surgical removal of necrotic bone in irradiated previous head and neck cancer patients compared to not receiving …

  • 66 views
  • 07 Nov, 2020
  • 1 location
Additional Minocycline Pleurodesis After Thoracoscopic Procedures for Primary Spontaneous Pneumothorax

To test if additional minocycline pleurodesis after thoracoscopic procedures can reduce the rates of ipsilateral recurrence for patients with primary spontaneous pneumothorax.

minocycline
spontaneous pneumothorax
vats
hemopneumothorax
pleurodesis
  • 0 views
  • 07 Nov, 2020
  • 1 location
SafetyNet Program for Opioid Use Disorder (OUD)

The principal aim of this study is to determine whether a novel biopsychosocial intervention following opioid overdose (OD) affects 1) the frequency of secondary opioid OD events and 2) the proportion of individuals who remain engaged in treatment for opioid use disorder (OUD) or are in remission at 30 days …

  • 0 views
  • 25 Jun, 2021
  • 2 locations
Personalized Medicine for Canadians With Hemophilia

treatment regimen matching the treatment needs of individual patients. The overarching goal of WAPPS-Hemo is to provide an easy-to-use web application supporting all the steps needed to accomplish tailoring

treatment regimen
hemophilia
severe haemophilia a
  • 2 views
  • 22 Sep, 2021
  • 6 locations
Effects of Mass Drug Administration of Azithromycin on Mortality and Other Outcomes Among 1-11 Month Old Infants in Mali

mass azithromycin treatments as an intervention for reducing childhood mortality, and to determine the most effective treatment regimen. The main study hypotheses in terms of mortality effect are: i

  • 0 views
  • 26 Jan, 2021
  • 1 location
Different Therapies in Treating Infants With Newly Diagnosed Acute Leukemia

from happening. It is not yet known which treatment regimen is most effective in treating acute leukemia. PURPOSE: This randomized clinical trial is studying how well different therapies work in

cyclophosphamide
pegaspargase
asparaginase
lymphoid leukemia
cancer
  • 12 views
  • 23 Jan, 2021
  • 5 locations
Onco-primary Care Networking to Support TEAM-based Care

for the intervention group using a dynamic treatment regimen approach. The investigators propose to randomize 800 adults with newly-diagnosed selected cancers treated with curative intent (breast

hypertension
cardiovascular disease
lung cancer
cancer care
chronic disease
  • 0 views
  • 15 Jun, 2021
  • 1 location
Intra-Operative Electron Boost and Hypofractionated Whole-Breast Irradiation During Breast-conserving Treatment (BCT)

proof of superiority of a new treatment regimen. The HIOB study concept is supposed to test the hypothesis whether such a combined schedule is superior (or iso-effective) towards "standard" RT in

carcinoma
breast irradiation
breast cancer
cancer
  • 0 views
  • 27 Jan, 2021
  • 1 location
Phase 3 Study of Pyrotinib Versus Docetaxel in Patients With Advanced Non-squamous NSCLC Harboring a HER2 Exon 20 Mutation Who Failed Platinum Based Chemotherapy

This is a randomized, positive-controlled, open-label, international multicenter, Phase 3 clinical study to compare the efficacy and safety of pyrotinib versus docetaxel in patients with advanced non-squamous NSCLC harboring a HER2 exon 20 mutation who failed platinum based chemotherapy.

  • 1 views
  • 01 Apr, 2021
  • 54 locations
Derazantinib Alone or in Combination With Paclitaxel Ramucirumab or Atezolizumab in Gastric Adenocarcinoma

The purpose of this study is to evaluate the efficacy of derazantinib monotherapy or derazantinib in combination with paclitaxel, ramucirumab, or atezolizumab in patients with HER2-negative adenocarcinoma of the stomach or gastro-esophageal junction harboring FGFR2 genetic aberrations (GA).

  • 0 views
  • 18 Aug, 2021
  • 73 locations