Found 266 clinical trials
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Multi-country trial
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Avelumab Program Rollover Study
The main purpose of this study is to monitor the safety and tolerability of avelumab in participants with solid tumors who continue treatment with avelumab under the same treatment regimen as in
- 9 views
- 19 Feb, 2021
- 20 locations
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Accepting pediatric ages
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Accepting Seniors
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100s of participants
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An interventional trial
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For all genders
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Genetic Disease
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Currently Recruiting
Personalized Medicine for Canadians With Hemophilia
treatment regimen matching the treatment needs of individual patients. The overarching goal of WAPPS-Hemo is to provide an easy-to-use web application supporting all the steps needed to accomplish tailoring
- 2 views
- 24 Jan, 2021
- 6 locations
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Multi-country trial
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Phase 2 trial
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Accepting pediatric ages
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AML
Leukemia. the study has two parts : Part 1 to define the Recommended Phase 2 Dose, and the Part 2 to evaluate efficacy and safety of midostaurin. All patients will follow the same treatment regimen
- 31 views
- 24 Feb, 2021
- 19 locations
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Phase 3 trial
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Accepting pediatric ages
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millions of participants
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An interventional trial
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For all genders
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Currently Recruiting
Effects of Mass Drug Administration of Azithromycin on Mortality and Other Outcomes Among 1-11 Month Old Infants in Mali
mass azithromycin treatments as an intervention for reducing childhood mortality, and to determine the most effective treatment regimen. The main study hypotheses in terms of mortality effect are: i
- 0 views
- 26 Jan, 2021
- 1 location
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Multi-country trial
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Efficacy & Safety of rAd-IFN Administered With Celecoxib & Gemcitabine in Patients With Malignant Pleural Mesothelioma
Malignant Pleural Mesothelioma (MPM) who have failed a minimum of 1 treatment regimen and a maximum of 2 treatment regimens, 1 of which must have been an anti-folate and platinum combination regimen.
- 24 views
- 26 Jan, 2021
- 53 locations
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Multi-country trial
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Accepting pediatric ages
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100s of participants
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An interventional trial
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For all genders
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Pediatrics/Neonatology
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Currently Recruiting
Different Therapies in Treating Infants With Newly Diagnosed Acute Leukemia
from happening. It is not yet known which treatment regimen is most effective in treating acute leukemia. PURPOSE: This randomized clinical trial is studying how well different therapies work in
- 12 views
- 23 Jan, 2021
- 5 locations
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Multi-country trial
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Pediatrics/Neonatology
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Currently Recruiting
A Study Evaluating Implementation Strategies for Cabotegravir (CAB)+ Rilpivirine (RPV) Long-acting (LA) Injectables for Human Immunodeficiency Virus (HIV)-1 Treatment in European Countries
CAB LA + RPV LA is an investigational HIV-1 treatment regimen administered as two individual intramuscular injections every 2 months following an oral lead-in (OLI) period. The overall objective
- 0 views
- 26 Jan, 2021
- 15 locations
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For females only
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Currently Recruiting
Intra-Operative Electron Boost and Hypofractionated Whole-Breast Irradiation During Breast-conserving Treatment (BCT)
proof of superiority of a new treatment regimen. The HIOB study concept is supposed to test the hypothesis whether such a combined schedule is superior (or iso-effective) towards "standard" RT in
- 0 views
- 27 Jan, 2021
- 1 location
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Multi-country trial
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Phase 1 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Derazantinib Alone or in Combination With Paclitaxel Ramucirumab or Atezolizumab in Gastric Adenocarcinoma
The purpose of this study is to evaluate the efficacy of derazantinib monotherapy or derazantinib in combination with paclitaxel, ramucirumab, or atezolizumab in patients with HER2-negative adenocarcinoma of the stomach or gastro-esophageal junction harboring FGFR2 genetic aberrations (GA).
- 0 views
- 04 Feb, 2021
- 38 locations
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Multi-country trial
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For males only
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Oncology
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Currently Recruiting
A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study
The purpose of this study is to collect long term safety data in subjects who are continuing to derive clinical benefit from treatment with Enzalutamide from the subjects participation in an enzalutamide clinical study sponsored by Astellas or Medivation (i.e., parent study) which has completed, at a minimum, the primary …
- 1404 views
- 28 Jan, 2021
- 131 locations