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Found 264 clinical trials
Treating Severe Brain-injured Patients With Apomorphine

follow-up. Shortly before and after the treatment regimen, the subjects will receive a multimodal assessment battery including neuroimaging exams. Primary outcome will be determined as behavioral

  • 7 views
  • 23 Jan, 2021
  • 2 locations
FOLFOX4 Combined With Endostar in Patients With Advanced Colorectal Cancer

FOLFOX4 plus Avastin has been suggested as firstline regimen for advanced colorectal cancer by NCCN, a new angiogenesis inhibitor, known as Endostar(Recombinant Human Endostatin), prolonged the overall survival, time to progression and improved response rate in metastatic lung cancer in a large phase III clinical trial in china, so we …

measurable disease
avastin
lung cancer
  • 12 views
  • 07 Nov, 2020
  • 1 location
Nab-paclitaxel and Gemcitabine in Metastatic Pancreatic Cancer

This is a single arm, open-label Phase II clinical trial to Evaluate the Efficacy and Safety of the Combination of Nab-paclitaxel and Gemcitabine in Treating Patients with metastatic pancreatic cancer.

  • 0 views
  • 22 Jan, 2021
  • 1 location
Pilot Study of Raltegravir Lipodystrophy IISP

The substitution of raltegravir for the NRTIs will result in some reversal of the long term adverse effect of lipodystrophy (specifically peripheral lipoatrophy) that is associated with the chronic use of NRTIs. Changing the HAART regimen in patients with a sustained virological response from a PI plus NRTI to a …

lipodystrophy
haart
raltegravir
  • 34 views
  • 08 Nov, 2020
  • 1 location
The Individualized M(X) Drug-resistant TB Treatment Strategy Study

This is a randomized controlled clinical trial comparing treatment success of a gene-derived individualized drug-resistant Tuberculosis regimen to a standard Tuberculosis regimen based on South African National Tuberculosis guidelines.

antiretroviral
mycobacterium
rifampin
pulmonary tuberculosis
treatment regimen
  • 21 views
  • 15 Feb, 2021
  • 1 location
Study of JK07 in Subjects With Heart Failure With Reduced Ejection Fraction (HFrEF)

This is a Phase 1, randomized, double-blind, placebo-controlled, single-ascending dose study to assess the safety, tolerability, immunogenicity, PK, and exploratory efficacy of JK07 in subjects 18 to 80 years of age with HFrEF 40%. Initially 5 cohorts are planned with the option to expand the study to a total of …

  • 2 views
  • 23 Feb, 2021
  • 6 locations
Futibatinib and Pembrolizumab Combination in the Treatment of Advanced or Metastatic Urothelial Carcinoma

The purpose of the trial is to evaluate a response to combination of Fibroblast Growth Factor Receptor (FGFR) inhibitor futibatinib and anti-programmed cell death-1 (PD-1) antibody pembrolizumab in patients with advanced or spreading urothelial cancer who are not candidates to receive a platinum-based treatment regimens. It also will help us …

  • 0 views
  • 13 Jun, 2021
  • 6 locations
Study of NAC of GA Therapy for Patients With BRPC

Gemcitabine plus nub-paclitaxel (GA) regimen was recently presented at an international oncology meeting and represents a new standard regimen in the treatment of metastatic pancreatic cancer. Therefore, it was decided to consider the balance of safety and efficacy on survival time as a preoperative chemotherapy, the investigators use the NAC-GA …

pancreatic adenocarcinoma
cancer
paclitaxel
gemcitabine
measurable disease
  • 18 views
  • 24 Jan, 2021
  • 18 locations
A Comparison of Hydrochlorothiazide and Metolazone in Combination With Furosemide in Congestive Heart Failure Patients

The purpose of this research study is to compare the effectiveness of hydrochlorothiazide or metolazone in combination with furosemide. Patients with heart failure suffer from swelling because of too much fluid in the body. Furosemide, hydrochlorothiazide, and metolazone are all water pills used to treat the swelling. For most patients, …

ejection fraction
beta-adrenergic blocking agents
edema
furosemide
diuretics
  • 8 views
  • 07 Nov, 2020
  • 1 location
Nasal Bridles and Repeat Endoscopic Procedures for Endoscopic Nasoenteric Tubes

In critically ill patients, nutrition is a major part of healing and recovery. In patients unable to tolerate oral feeding, nasoenteric tube feeding (a tube placed from the nose to the stomach or small intestine) provides a safe alternative for feeding. Some patients require these tubes to be placed endoscopically …

  • 0 views
  • 21 May, 2021
  • 2 locations