Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 272 clinical trials
Dolutegravir Plus Lamivudine Simplified Therapy

Dolutegravir (DTG) is one type of integrase inhibitor, lamivudine (3TC) is one type of reverse transcriptase inhibitor, both of which are HIV medicine prevents HIV from self-multiplying, reduces the viral load. The data of the existing randomized controlled clinical studies show that the simplified two-drug DTG-based regimen is similar to …

osteoporosis
integrase inhibitors
hiv-1 rna
dolutegravir
hiv-1 rna measurement
  • 2 views
  • 22 Jan, 2021
ATHN 7: Hemophilia Natural History Study

This is a real-world study of the safety of the treatments used for people with hemophilia. The study will follow people with hemophilia A or B from across the country for about 4 years as they receive treatment. The hemophilia treatment center (HTC) physician and participant will decide on the …

  • 4 views
  • 25 Jan, 2021
  • 37 locations
AIMS Cancer Outcomes Study

The overall aim is to describe disease-free survival (DFS) in early stage cancer patients and three-year overall survival (OS) outcomes in advanced stage cancer patients receiving Advanced Integrative Oncology (AIO) treatment in a prospective consecutive case series outcomes study. We will collect data and study outcomes for patients with cancer …

cancer
primary cancer
  • 0 views
  • 24 Jan, 2021
  • 1 location
Qualitative Understanding of Experiences With the SIMPLIFY Trial

This qualitative longitudinal study is designed to elicit and thematically analyze the perspectives of SIMPLIFY subjects about treatment withdrawal research and treatment burden in the context of triple combination CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) modulator therapy (TCT). Cohorts will be determined based on sub-groups of the assigned treatment arms …

  • 0 views
  • 13 Feb, 2021
  • 2 locations
LIFE - Lung Cancer Immunotherapy Frailty Effect

The LIFE study (Lung cancer, Immunotherapy, Frailty, Effect) is investigating the unselected 'real life' non-small cell lung cancer (NSCLC) population treated with immune checkpoint inhibition.

  • 0 views
  • 27 Jan, 2021
  • 1 location
Chemotherapy Host Response and Molecular Dynamics in Periampullary Cancer

The CHAMP (Chemotherapy, Host response And Molecular dynamics in Periampullary cancer) study is a prospective, single-arm observational study that started Sept 1 2018. Patients diagnosed with pancreatic or other periampullary adenocarcinoma undergoing adjuvant och palliative chemotherapy are invited to participate. The study will examine the tumors' molecular dynamics and how …

adenocarcinoma
gemcitabine
periampullary adenocarcinoma
cancer chemotherapy
immunostimulant
  • 4 views
  • 18 Mar, 2021
  • 3 locations
Use of Wearables for Early Detection of Complications After Major Acute Abdominal Surgery

The purpose of the study is to investigate whether glucose profile, sleep disturbances and heart rate variability measured with wearable devices is associated with postoperative recovery and complications within 30 days after major emergency abdominal surgery. The study is designed as an explorative, prospective cohort study. 40 patients undergoing major …

  • 1 views
  • 24 Jan, 2021
  • 1 location
Excretion of Acetylamantadine (AA) by Lung Cancer Patients During a Chemotherapy Regimen

This study is designed to determine if changes in acetyl amantadine (AA) metabolism with systemic chemotherapy - reflective of SSAT1 activity - are predictive of response to systemic therapy in patients with lung cancer. Ten patients with adenocarcinoma and 10 with small-cell cancer who are at American Joint Committee on …

adenocarcinoma
cancer chemotherapy
lung carcinoma
lung cancer
cancer
  • 2 views
  • 25 Mar, 2021
  • 2 locations
ATHN 8: PUPs Matter Study

This is a multi-center cohort study of approximately 250 previously untreated patients (PUPs) with congenital moderate to severe hemophilia A or B in a network of up to 50 US Hemophilia Treatment Centers (HTCs). Participants will be followed as they receive their first 50 exposure days (ED) to clotting factor …

coagulation factor
bleeding tendency
severe haemophilia a
christmas disease
Factor VIII
  • 1 views
  • 25 Jan, 2021
  • 26 locations
Short-course Radiotherapy (5 6Gy/7Gy/8Gy) Followed by Neo-adjuvant Chemotherapy for Locally Advanced Rectal Cancer

Preoperative radiotherapy followed by total mesorectal excision (TME) has been recommended as the preferred treatment method for locally advanced rectal cancer. Similar rates of local control, survival and toxicity were observed in preoperative long-course radiotherapy (LCRT) (45-50.4 Gy in 25-28 fractions) and short-course radiotherapy (SCRT) of 25 Gy in five …

total mesorectal excision
renal function
adenocarcinoma
  • 13 views
  • 25 Jan, 2021
  • 1 location