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Found 511 clinical trials
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Depression - Treatment Resistant

Still feeling symptoms of Depression after having taken a prescription Antidepressant?  If so, participating in our medical research study of an investigational drug may be an option for you.

depressed mood
antidepressants
depressive episode
depressive symptoms
  • 274 views
  • 05 Apr, 2021
  • 1 location
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Treatment Resistant Depression Study

Treatment Resistant Depression Study

  • 1266 views
  • 08 Nov, 2020
  • 1 location
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A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of Brexipiprazole as Adjunctive Therapy in the Maintenance of Adults With Major Depressive Disorder

A study to compare the efficacy of brexpiprazole to placebo as adjunctive therapy to antidepressant therapy for the maintenance treatment in adults with major depressive disorder.  

depressive disorder
antidepressant therapy
  • 75 views
  • 23 Nov, 2020
  • 1 location
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A Phase 2a Randomized, Double-blind, Placebo-Controlled, Parallel-Group, Multi-center Study Investigating the Efficacy, Safety, Tolerability and Pharmacokinetics of JNJ-XXX in Subjects with Major Depressive Disorder

A study to evaluate the efficacy of JNJ-XXX compared to placebo when administered as adjunctive treatment in subjects with MDD partially responsive to SSRI/SNRI treatment in terms of reduction of symptoms of depression.  

depressed mood
selective serotonin reuptake inhibitors
depressive symptoms
  • 49 views
  • 23 Nov, 2020
  • 1 location
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A Double-Blind, Placebo-Controlled Study of Cariprazine as an Adjunct to Antidepressants in the Treatment of Patients With Major Depressive Disorder Who Have Had an Indadequate Response to Antidepressants Alone

A study to evaluate the efficacy, safety, and tolerability of cariprazine compared with placebo as an adjunctive treatment to ongoing antidepressant therapy in patients with major depressive disorder who have had an inadequate response to antidepressants alone.  

depressive disorder
antidepressants
antidepressant therapy
  • 94 views
  • 23 Nov, 2020
  • 1 location
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A Phase 2a, Randomized, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of MK-1942 Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression

Merck Sharp & Dohme Corp. is conducting this trial to test the investigational drug MK-1942 in people with treatment-resistant depression. The purpose of this trial is to test the safety

  • 0 views
  • 06 Apr, 2021
  • 1 location
featured
A Phase 2a, Randomized, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of MK-1942 Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression

The main purpose of this study is to assess the efficacy and safety of daily and intermittent dosing of MK-1942 compared to placebo among participants with Treatment-Resistant Depression (TRD

  • 0 views
  • 23 Mar, 2021
  • 1 location
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MDD

Do you or a loved one experience major depressive disorder (MDD)? Consider a clinical research study testing the safety and effectiveness of an investigational drug for individuals with depression.

  • 0 views
  • 05 Apr, 2021
  • 1 location
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A Two-Part Study of CLE-100 as an Adjunct Therapy in Subjects With Major Depressive Disorder

The pharmaceutical company Clexio is studying an investigational drug called CLE-100 and its effectiveness in treatment of major depressive disorder (MDD) symptoms. This Study has two parts: part A and part B. Part A is completed and had enrolled 16 participants suffering from MDD to evaluate the safety of the …

  • 0 views
  • 05 Apr, 2021
  • 1 location
featured
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of Brexpiprazole as Adjunctive Therapy in the Maintenance Treatment of Adults With Major Depressive Disorder

Brexpiprazole is a medication being studied as a possible treatment for adjunctive treatment for Major Depressive Disorder (MDD). It was first approved in the United States for the treatment of schizophrenia and as an adjunctive therapy to antidepressants for the treatment of MDD. Otsuka is conducting this study to find …

  • 0 views
  • 06 Apr, 2021
  • 1 location