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Found 2 clinical trials
A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia

The overall aim of this study is to determine if epigenetic priming with a DNA methyltransferase inhibitor (DMTi) prior to chemotherapy blocks is tolerable and carries evidence of a clinical efficacy signal as determined by minimal residual disease (MRD), event-free survival (EFS), and overall survival (OS). Tolerability for each of …

idarubicin
leukemia
azacitidine
cancer
colony stimulating factor
  • 41 views
  • 11 Aug, 2022
  • 12 locations
Haplo vs. URD in AML

This study compares haplo-identical family donor stem cell transplantation (haplo SCT) to matched unrelated donor transplantation (URD SCT) in adult patients with acute myeloid leukemia (AML) with the hypothesis that haplo SCT is as good as URD SCT. Background A haplo-identical family donor is a relative sharing 50% of the …

mycophenolate mofetil
cyclophosphamide
graft versus host disease
busulfan
fludarabine
  • 4 views
  • 26 Feb, 2022
  • 2 locations