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Found 36 clinical trials
DOvEEgene Phase III Trial (DOvEEgeneIII)

delayed. The McGill research group had showed in the DOvEE trial (NCT02296307), that fast-track assessment with transvaginal ultrasound scans (TVUS) and serial CA125 of women with vague symptoms

Accepts healthy volunteers
  • 04 Oct, 2022
  • 2 locations
A Phase 3b, Randomized, Double-blind, Placebo-controlled, 24-week Study to Assess the Efficacy and Safety of Fezolinetant in Menopausal Women Suffering From Moderate to Severe Vasomotor Symptoms (Hot Flashes) and Considered Unsuitable for Hormone Replacement Therapy (Daylight)

Week 2 and Week 24, the women will have an ECG to check their heart rhythm. Women who have a uterus will also have a test called a transvaginal ultrasound. A probe is gently placed inside the vagina

  • 23 Oct, 2022
  • 10 locations
Efficacy of Transvaginal Ultrasound-guided Aspiration for Treatment of Tubo-ovarian Abscess Compared With Laparoscopy (Pactol)

"Tubo-ovarian abscess (TOA) include pyosalpinx, ovarian abscess, tubo-ovarian abscess and Douglas abscess. The only randomized study evaluating TOA treatment reported a higher cure rate (90 versus 65%) when antibiotic therapy is associated with abscess evacuation. TOA evacuation can be performed by surgery or by drainage. No studies have compared success …

  • 04 Oct, 2022
  • 1 location
Single Versus Double Suture Cervical Cerclage to Prevent Preterm Birth

Cerclage placement is known to be beneficial in prevention of preterm birth when placed inn a certain subset of patients. Clinically, the number of sutures can also vary by surgeon preference to one or two sutures in one procedure. This is often decided in the operating room (OR) on the …

  • 26 Mar, 2021
  • 1 location
Intra-operative Ultrasound Guided Laparoscopic Ovarian Cystectomy as a Method of Fertility Preservation (UGLOC)

Title Intra-operative ultrasound guided laparoscopic ovarian cystectomy (UGLOC) as a method of fertility preservation in the management of benign ovarian cysts. Background Approximately 10% of women in the United Kingdom (UK) will undergo surgery for the presence of an ovarian mass during their lifetime. Ovarian surgery, however, is not without …

Accepts healthy volunteers
  • 19 Apr, 2022
  • 1 location
Cerclage for Twins With Short Cervical Length ≤ 15mm (TWIN-UIC)

gestations and cervical length 15mm, diagnosed by transvaginal ultrasound between 16 to 23 6/7 weeks of gestation.

cervical cerclage
transvaginal ultrasound
  • 30 Jan, 2022
  • 7 locations
Evaluating the Performance of Morphology Index in Surgical Decision-Making for Ovarian Tumors

The present investigation will prospectively evaluate whether serial transvaginal ultrasonography with Morphology Index (MI) can further reduce false positive results by more accurately distinguishing benign from malignant ovarian tumors. If there is no change in the detection of true positive cases, the result will be an increase in the positive …

cancer of the ovary
breast cancer
  • 24 Feb, 2022
  • 1 location
Use of the CA 125 Algorithm for the Early Detection of Ovarian Cancer in Low Risk Women

The goal of this clinical research study is to evaluate a method involving a blood test, called CA-125, that may be helpful in the early detection of ovarian cancer in women who are at low risk.

Accepts healthy volunteers
cancer of the ovary
cancer chemotherapy
cancer antigen 125
  • 16 Oct, 2022
  • 11 locations
GnRH Agonist for Dual Trigger in IVF and for Luteal Phase Support in FET

The objectives of this study are to compare the efficacy of the dual trigger group vs the hCG trigger group on the live birth rate in women undergoing IVF and the efficacy of the agonist in LP group vs the placebo group on the live birth rate in women undergoing …

gonadotrophin releasing hormone analogue
  • 27 May, 2022
  • 1 location
Letrozole in Stimulated IVF Cycles

In-vitro fertilization (IVF) is the treatment of choice for couples with prolonged infertility. The treatment usually involves hormonal stimulation of the ovaries by follicle stimulating hormone (FSH), followed by surgical removal of eggs which are then mixed with sperm in the laboratory to create embryos. The success rates of IVF …

in vitro fertilization
ovarian stimulation
antral follicle count
  • 19 Apr, 2022
  • 2 locations