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Found 109 clinical trials
Active Temperature Management After Cardiac Surgery and Its Effect on Postoperative Cognitive Dysfunction

This study will assess the effect of active postoperative temperature management and its effect on the cognitive function in patients following coronary artery bypass graft (CABG) surgery to determine if active postoperative temperature management to maintain normothermia reduces postoperative cognitive dysfunction (POCD) in this population. Additionally, the investigators will explore …

cognitive impairment
coronary artery bypass graft
bypass graft
heart surgery
  • 15 Feb, 2022
  • 1 location
Assessing Neurocognition After Cerebrovascular Intervention

Decreased blood flow to the brain can cause decreased cognitive function. Carotid disease can result in decreased blood flow to the brain. The investigators seek to assess this relationship prospectively through performing a battery of neurocognitive assessments, collection of serum markers of inflammation, and through neuroimaging at two points before …

carotid artery stenosis
carotid disease
  • 16 Feb, 2021
  • 1 location
Randomized Controlled Trial of Alert-Based Computerized Decision Support for Optimizing Low-Density Lipoprotein Management

A 400-patient U.S.-based single-center Quality Improvement Initiative in the form of a randomized controlled trial focused on the feasibility of implementation of this electronic alert-based CDS (EPIC BPA) based on LDL-C values. The 400 patients will be comprised of 200 in the "Hospitalized Patient Cohort" and 200 in the "Outpatient …

  • 29 Oct, 2021
  • 1 location
Emergent Microsurgical Intervention in Acute Stroke Patients After Mechanical Thrombectomy Failure Trial (EMIAS)

With all of the gains that have been achieved with endovascular mechanical thrombectomy revascularization and intravenous thrombolysis logistics, there is still a subgroup of patients with salvageable brain tissue for whom persistent emergent large vessel occlusion (ELVO) portends a catastrophic outcome. Study aims to test the safety and efficacy of …

  • 25 Mar, 2022
  • 2 locations
Study of Apixaban in Patients Receiving Hemodiafiltration

Atrial fibrillation (AF) is a prevalent and serious disease in hemodialysis (HD) patients. Untreated AF increases the risk of deaths related to cardiovascular events and multiplies the risk of strokes by 5. Anticoagulation with warfarin significantly reduces the incidence of ischemic strokes in the general population, has a long half-life, …

anticoagulation therapy
  • 19 Jul, 2021
  • 1 location
Improved Prediction of Recurrent Stroke and Detection of Small Volume Stroke (ENCLOSE)

patient will however suffer from a more distal occlusion resulting in small volume stroke or a transient ischemic attack (TIA). Small ischemic lesions are hard to detect with current acute stroke

ct scan
transient ischemic attack
  • 12 Feb, 2022
  • 1 location
Assessment of Compliance With European and French Guidelines for the Management of Dyslipidaemias (OBDYSLIP)

; 140/90 mmHg), presence and type of CVD (coronary artery disease, stroke and transient ischemic attack, peripheral arterial disease), were collected at admission. LDL-C, HDL-C and triglycerides levels

  • 27 Feb, 2022
  • 1 location
Real-world Study on Edoxaban Treatment for Patients With Non-valvular Atrial Fibrillation in China (ETNA-AF-CHINA)

The safety of edoxaban treatment will be examined using real-world clinical evidence from adult patients with non-valvular atrial fibrillation (NVAF) indications in routine clinical practice.

  • 30 Jun, 2022
  • 86 locations
FDG an Myocardial Infarction: The PIAF Trial

In order to define distinct and reliable arterial 18Fluorodeoxyglucose (FDG) thresholds identifying patients at risk for cardiovascular events, patients with a history of myocardial infarction will be included in this international multicenter trial. Non-enhanced whole-body FDG PET/CT will be performed in all patients and the arterial FDG uptake in the …

  • 10 Dec, 2021
Long-term Enlarged Survival After an Enhanced Recovery Protocol (LESAS). (LESAS)

The main objective of this study is to analyze the impact on three years survival of an enhanced recovery program (PRI) after radical surgery for colorectal cancer. As secondary objectives, we propose to analyze the weight of each of the predefined items in the oncological results as well as the …

  • 22 Mar, 2022
  • 10 locations