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Found 112 clinical trials
Women's IschemiA TRial to Reduce Events In Non-ObstRuctive CAD (WARRIOR)

MACE as death, nonfatal MI, nonfatal stroke/transient ischemic attack (TIA) or hospitalization for heart failure or angina. Secondary outcomes include quality of life, time to "return to duty"/work

angina pectoris
myocardial infarction
coronary ct
  • 26 Feb, 2022
  • 84 locations
The Impact of a Smartphone-based Personalized Intervention on Cognitive and Cerebrovascular Health in CIRCLE-CHINA

This smartphone-based personalized multiple intervention study aims to prevent cognitive impairment and reduce dementia and cerebrovascular events in 45-74 year old persons with high risk of stroke in China. The investigators plan to monitor and manage participants' behavioral and health (vascular risk factors control, sleep quality, mental health and cognitive …

cognitive training
neurological disorder
Accepts healthy volunteers
atrial fibrillation
  • 24 Jan, 2022
  • 1 location
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG (PACES)

The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying …

antiplatelet therapy
anticoagulation therapy
coronary artery bypass graft
vitamin k antagonist
  • 27 Apr, 2022
  • 43 locations
Aspirin to Target Arterial Events in Chronic Kidney Disease (ATTACK)

This study aims to find out whether people with chronic kidney disease [CKD] should take low dose aspirin to reduce the risk of first heart attack or stroke (cardiovascular disease [CVD]). CKD is common and is associated with an increased risk of CVD. CVD is caused by small blood clots …

chronic disease
cardiovascular disease
myocardial infarction
primary prevention
  • 25 Mar, 2022
  • 1 location
Beta-blockers to Patients With Chronic Obstructive Pulmonary Disease

Background: In patients with chronic obstructive pulmonary disease (COPD) and concomitant cardiovascular conditions cardio-selective beta-blockers reduce mortality and can be used without significant negative effects on lung function or respiratory symptoms. Observational studies indicate that beta-blocker therapy in COPD even without overt cardiovascular disease, is associated with reduced risk for …

copd exacerbation
pulmonary function test
respiratory symptom
  • 18 May, 2022
  • 1 location
GLP-1 and Hyperoxia for Organ Protection in Heart Surgery (GLORIOUS)

Patients undergoing open heart surgery are at risk of suffering damage to the heart, brain and kidneys. This study is designed as a 2-by-2 randomized clinical trial with the purpose of investigating the organ protective effects of the glucagon-like-peptide-1 (GLP-1) agonist Exenatide versus placebo and restrictive versus liberal oxygenation during …

ischemic heart disease
heart surgery
percutaneous coronary intervention
arterial disease
  • 27 Jan, 2022
  • 1 location
Personalized Antiplatelet Secondary Stroke PRevenTion (PASSPoRT)

This is a descriptive study designed to evaluate the safety and feasibility of a precision medicine approach to antiplatelet selection for secondary stroke prevention.

  • 09 Feb, 2022
  • 1 location
AcoArt VI / Vertebral Artery Ostium Stenosis in China

The purpose of this study is to determine whether DEB is not inferior to common bare metal stent using under in long-term vessel patency and inhibiting restenosis in Vertebral Artery Ostium Stenosis

  • 11 Dec, 2021
  • 1 location
Efficacy of Ticagrelor Plus Aspirin in Minor Non-cardioembolic Ischemic Stroke

This is a randomized, controlled, active comparator arm, outcome assessor blind, parallel group design on 90 patient with diagnosis of ischemic stroke admitted in Bou-Ali Sina Hospital, Sari,Iran.The aim of study is assess the efficacy of ticagrelor plus aspirin in reduce of minor non-cardioembolic ischemic stroke or high risk TIA …

  • 12 Sep, 2021
  • 2 locations
Multiple Interventions to Accelerate the Return to the Pre-event Level of Functioning After a TIA and Minor Stroke

The occurrence of a transient ischemic attack (TIA) or a minor stroke is frequently assumed as a temporary and non-disabling event. Nevertheless, patients can experience subtle but meaningful

  • 16 Jun, 2022
  • 1 location