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Found 7 clinical trials
DLCL002 Protocol for Patients With High Risk Aggressive B-cell Lymphoma

Patients eligible for the study will receive R-DA-EDOCH as the induction therapy and be evaluated by PET CT after the fourth cycle. Patients achieve CR at interim-PET(Deauville score 1-3) will receive either ASCT or the remaining 4 cycles of R-DA-EDOCH, while those achieve PR(Deauville score 4-5) will be rescued by …

b-cell lymphoma
dexamethasone
lenalidomide
vincristine
rituximab
  • 0 views
  • 24 Mar, 2022
  • 1 location
Tislelizumab in Combination With Lenalidomide in Refractory and Relapsed Elderly Patients With Non-GCB DLBCL

Aim of this study will evaluate the efficacy and safety of tislelizumab in combination with lenalidomide in in patients with relapsed or refractory Elderly Patients with non-GCB Diffuse Large B Cell Lymphoma

  • 0 views
  • 25 Mar, 2021
  • 1 location
Camrelizumab in Combination With Apatinib in Refractory and Relapsed DLBCL

This study will evaluate the efficacy and safety of camrelizumab in combination with apatinib in in patients with relapsed or refractory diffuse large B cell lymphoma failed from second line chemotherapy.

b-cell lymphoma
ct scan
measurable disease
platelet count
follicular lymphoma
  • 0 views
  • 21 Mar, 2021
  • 1 location
Toripalimab Plus Rituximab Followed by R-CHOP for Elderly Patients With Untreated Diffused B Cell Lymphoma

Phase I portion of this study will evaluate the efficacy and saftey of toripalimab plus rituximab in treating untreated elderly diffuse large B cell lymphoma patients. The aim of phase II portion of this study will evaluate the efficacy and saftey of toripalimab plus rituximab followed by R-CHOP(rituximab, cyclophosphamide, doxorubicin, …

b-cell lymphoma
ct scan
measurable disease
prednisone
cancer chemotherapy
  • 1 views
  • 30 Apr, 2022
  • 1 location
Anti-CD19 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma

This study will assess safety and feasibility of infusing genetically modified autologous T cells transduced to express a chimeric antigen receptor targeting the B cell surface antigen Cluster of Differentiation 19 (CD19)

immunoglobulin
lymphoma
refractory non-hodgkin's lymphoma
b-cell small lymphocytic lymphoma
rituximab
  • 0 views
  • 13 May, 2022
  • 1 location
A Study of Zilovertamab Vedotin (MK-2140) (VLS-101) in Participants With Hematologic Malignancies (MK-2140-001)

The purpose of this study is to evaluate the safety, pharmacokinetics, immunogenicity, and efficacy of zilovertamab vedotin given intravenously (IV) across a range of dose levels in participants with previously treated hematological cancers including acute lymphocytic leukemia (ALL), acute myeloid leukemia (AML), Burkitt lymphoma (BL), chronic lymphocytic leukemia/small lymphocytic lymphoma …

immunoglobulin
lymphoma
chronic lymphocytic leukemia
lymphadenopathy
b-cell small lymphocytic lymphoma
  • 48 views
  • 22 Mar, 2022
  • 11 locations
Axicabtagene Ciloleucel:Neurocognitive and Patient-Reported Outcomes

The purpose of the study is to assess self-reported side effects and neurocognitive (brain, mood and thinking) functioning among patients treated with commercial axi-cel therapy.

cancer
b-cell lymphoma
follicular lymphoma
  • 0 views
  • 24 Mar, 2022
  • 1 location