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Found 39 clinical trials
Prehabilitation in Esophageal Surgery (PRESS) (PRESS)

Despite important clinical improvements, esophageal cancer surgery is still associated to a high rate of postoperative complications. Recent ERAS (Enhanced Recovery After Surgery) Society guidelines underline the possible role of prehabilitations' programs in reducing postoperative morbidity. In this trial, 200 patients, scheduled for esophageal cancer resection, will be randomly assigned …

  • 08 Jul, 2022
  • 1 location
Impact of Pancreatic Endoscopic Drainage on Exocrine Pancreatic Function in Unresectable Pancreatic Cancer (DEPARA)

Background: exocrine pancreatic insufficiency (IPE), frequent in patients with pancreatic cancer, plays a major role in malnutrition and cachexia with a significant impact on survival, quality of life and tumor progression. IPE due to obstruction of the main pancreatic duct and atrophy of pancreatic parenchyma proximal to the tumor could …

  • 22 Mar, 2022
  • 1 location
Different Treatment Strategies on Prognosis of Acute Ischemic Stroke(AISDTS)

AISDTS is a prospective registry study, in which clinical information, examination and imaging data of patients with acute ischemic stroke receiving different treatment strategies were collected, grouped and statistically analyzed, and corresponding clinical prediction models were constructed to explore the role of clinical biological indicators in the occurrence and development …

  • 16 Jun, 2022
  • 1 location
Cohort of Patients With Rare Iron Overloads Excluding C282Y Homozygosity (HEPCICOR)

The study explores the hepcidin deficiency causes of rare iron overload (excluding C282Y homozygosity), and aim to characterize this iron overload in term of clinical, biological, genetic and functional spacificities.

  • 13 May, 2022
  • 8 locations
Prevalence of FID and QoL in Patients With Oncological and With Haematological Malignancies

Prospective single-center observational study assessing prevalence of FID (Laboratory work-up) and Quality of Life (Questionnaire) in adult patients with oncological and with haematological malignancies within four weeks prior to disease-directed therapy.

  • 06 May, 2022
  • 1 location
Clinical and Basic Investigations Into Known and Suspected Congenital Disorders of Glycosylation

Background Proteins, fats, and other molecules are the body s building blocks. Many of these molecules must have sugars, or chains of sugars, attached to work properly. People with congenital disorders of glycosylation (CDGs) cannot attach these sugars or sugar chains properly. A child or adult with a CDG can …

  • 21 Jul, 2022
  • 1 location
Predicting the Future: Incipient Tuberculosis

levels of the iron homeostasis markers (Hepcidin, Ferritin and Transferrin). Identified index cases who agree to participate will refer their household or close contacts to also join the study

  • 01 Aug, 2021
  • 3 locations
Ambulatory Blood Pressure in HFPEF Outcomes Global Registry

Heart failure and preserved ejection fraction (HFPEF) is a disease with increasing prevalence world wide. Due to its etiological and prognostic relationship with hypertension, it is highly interesting to know the characteristics and influence of Blood pressure levels and of the hemodynamic biomarkers, measured by Ambulatory Blood Pressure measurement in …

  • 04 Mar, 2021
  • 1 location
Decompensation of Cirrhosis and Iron Metabolism

characterizing the impact of exposure to non-transferrin-bound iron in acute on chronic liver failure on short-term mortality. Overall, a better understanding of the physiopathological mechanisms of iron

gastric varices
  • 27 Jul, 2021
  • 1 location
.Patient Blood Management Program in Liver Transplantation (PBM-THO)

(transferrin saturation less than 20%), we could improve the hemoglobin level, which would allow a wider margin for the transfusion of red cell concentrates.

  • 27 Apr, 2022