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Found 39 clinical trials
Ascorbic Acid Administration in the Treatment of Anemia in Chronic Hemodialysed Patients (FeVitC)

The administration of ascorbic acid seemed to increase the iron available for erythropoiesis, thus improving the anemia response to the treatment. The investigators therefore aimed to evaluate the effects of intravenous ascorbic acid administration in hemodialysed patients with iron overload.

  • 0 views
  • 28 Feb, 2022
  • 1 location
Effect of Intravenous Ferric Carboxymaltose on Hemoglobin Response and Transfusion in Patients With Iron Deficiency Anemia After Off-Pump Coronary Artery Bypass Grafting

In this prospective open-label randomized tral, 100 patients with elective off-pump coronary artery bypass (OPCAB) or minimal invasive direct coronary bypass (MIDCAB) surgery were enrolled. Before surgery, if a patient had iron deficiency anemia, the patient was randomized to receive Ferinject(Ferric carboxymaltose, n=50) or placebo (normal saline, n=50), respectively. A …

off-pump coronary artery bypass
bypass graft
  • 0 views
  • 31 May, 2021
  • 1 location
Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders

Preclinical and clinical data as well as mechanistic justification have been presented suggesting citicoline and pregnenolone are each promising treatments for alcohol use in BPD. Both appear to have favorable side effect profiles and no known drug-drug interactions. Thus, they have the potential to be safely used in a dual …

bipolar disorder
substance use
lamotrigine
alcohol use disorder
valproate
  • 1218 views
  • 25 Jul, 2022
  • 1 location
Breast Cancer and Intrauterine Contraception

The present work seeks an alternative to the copper IUD for contraception in breast cancer patients, evaluating the satisfaction and continuity of the copper and silver IUD, as well as the quality of life, compared to the copper IUD, especially in the regarding the menstrual bleeding pattern of these patients …

cancer
intrauterine contraception
carcinoma
breast carcinoma
copper
  • 0 views
  • 16 Dec, 2021
  • 1 location
Evaluation and Treatment of Iron Deficiency in Ovarian Cancer Patients

This study tests the hypothesis that IV iron sucrose infusions given to iron deficient ovarian cancer patients prior to debulking surgery can improve pre-operative iron stores and decrease transfusion of packed red blood cells in the peri-operative period. 21 participants at least 18 years of age with epithelial ovarian cancer …

iron deficiency anemia
anemia
cancer
malnutrition
iron
  • 101 views
  • 09 Feb, 2022
  • 1 location
The Gut Microbiome as an Indicator of Readiness for Head & Neck Cancer Surgery

The purpose of this study is to understand how a pre-operative nutritional intervention alters the gut microbiome and improves outcomes after major head and neck cancer surgery.

neck dissection
  • 0 views
  • 11 Mar, 2022
  • 1 location
Theta Burst Stimulation as a Tool to Decrease Drinking in Treatment-seeking Alcohol Users

There is growing interest in the utilization of transcranial magnetic stimulation (TMS) as a novel, non-pharmacologic approach to decreasing alcohol use among treatment-seeking individuals with Alcohol Use Disorder (AUD). The results of this study will be used to determine which of the 2 proposed TMS strategies has a larger effect …

alcohol use disorder
anxiety
heavy drinking
  • 0 views
  • 12 May, 2022
  • 1 location
A Study of Perioperative Oral Nutritional Support for Patients Having Surgery for Colon Cancer, Peri-Nutri

This is a multicenter, unblinded, randomized study. The aim of this study is to research whether preoperative and postoperative oral nutritional supplement (ONS) (Resource 2.5 Compact/fibre compact) used at least 2 weeks prior the surgery and 10 days after surgery can improve the nutritional status of a colon cancer patient …

cancer
adenocarcinoma of colon
adenocarcinoma
malnutrition
nutritional supplementation
  • 3 views
  • 27 May, 2022
  • 1 location
Epigenetics, Vitamin C, and Abnormal Blood Cell Formation - Vitamin C in Patients With Low-Risk Myeloid Malignancies (EVITA)

The primary purpose of this multi-centre, randomized, placebo-controlled, double-blind phase II study is to investigate if oral vitamin C may change the biology of low-risk myeloid malignancies; i.e., clonal cytopenia of undetermined significance (CCUS), low-risk myelodysplastic syndromes (MDS), and chronic myelomonocytic leukemia (CMML)-0/1 by reversing the epigenetic changes characteristic of …

bone marrow procedure
cancer
myelomonocytic leukemia
chronic myelomonocytic leukemia
cytopenia
  • 52 views
  • 14 Feb, 2022
  • 4 locations
Clinical Burden of Anemia in Inflammatory Bowel Disease: Therapeutic Trial

Anemia is the most common extraintestinal manifestation of inflammatory bowel diseases (IBD), Although most cases of anemia in IBD are due to iron deficiency, many patients with iron deficiency anemia (IDA) are not treated with iron supplementation. In addition, it has not been firmly established which iron supplementation modality provides …

fatigue
enteropathy
  • 0 views
  • 26 Jan, 2021
  • 1 location