Found 95 clinical trials
Gestational Diabetes and Pharmacotherapy (GAP) (GAP)
The goal of this study is to compare two different thresholds for initiation of medical treatment for GDM. Pregnant women diagnosed with GDM will be randomized to either start pharmacotherapy when they have reached at least 20% or at least 40% of capillary blood glucose (CBG) values above the target …
- 10 views
- 04 Oct, 2022
- 1 location
Research on Risk Factors and Comprehensive Intervention Measures of Polycystic Ovary Syndrome Complicated With Mental Diseases Such as Depression and Anxiety (PCOS)
The current study intends to establish a prediction method and evaluation system for polycystic ovary syndrome (PCOS) complicated with affective disorder, such as depression and anxiety, through the epidemiological investigation. Randomized controlled studies on the efficacy of various intervention methods should be carried out to develop early intervention measures and …
- 8 views
- 27 Oct, 2022
- 1 location
IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy
This treatment trial evaluates the addition of an anti-tumor necrosis factor-alpha drug, certolizumab, to usual treatment (a heparin agent and low-dose aspirin) in pregnant women with antiphospholipid syndrome (APS) and repeatedly positive tests for lupus anticoagulant (LAC) to determine if this regimen will improve pregnancy outcomes. All enrolled patients will …
- 243 views
- 14 May, 2022
- 2 locations
Closed-loop Insulin Delivery In Type 1 Diabetes Pregnancies (CIRCUIT) (CIRCUIT)
This trial will assess the efficacy of the Tandem t:slim X2 insulin pump with Control IQ technology compared with standard insulin delivery plus CGM in pregnant women with type 1 diabetes.
- 2 views
- 03 Sep, 2023
- 5 locations
Maternal Stress on Human Milk and Infant Outcomes
The overarching purpose of this study is to determine if a modified 8-week mindfulness-based intervention (with a focus on self-compassion; MBSC) will reduce stress and increase self-compassion in mothers of preterm infants and beneficially modify the human milk produced, and subsequently improve infant health.
- 0 views
- 10 Sep, 2023
- 1 location
Fetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior
Determine 1) the impact of abnormal fetal cerebrovascular physiology with neurodevelopmental delay (ND) outcomes and 2) how this relationship is modified by patient and environmental factors such as chronic congenital heart disease (CCHD) lesion, maternal-fetal environment, and social determinants of heath (SDOH) in a diverse population using a multicenter design. …
- 0 views
- 09 Apr, 2023
- 1 location
Achievement and Adherence to Behavioral Health Goals in the Setting of Patient-Directed Goal Choice
Health care decisions should include patients' health outcome goals and care preferences so as to enable a unified set of individualized patient outcome goals, rather than disparate disease-specific goals that do not reflect patient choice and commitment. This study utilizes a skilled professional interview and a simple tablet-based tool to …
- 0 views
- 07 Jul, 2022
- 1 location
CAPO: Continuous Glucose Monitoring in A2 Gestational Diabetes and Pregnancy Outcomes (CAPO)
This study will utilize continuous glucose monitoring in women with A2 gestational diabetes. Women will be randomized to continuous glucose monitoring or routine care with fingersticks to check their blood glucose four times daily. It is hypothesized that women in the continuous glucose monitoring arm will have a lower incidence …
- 0 views
- 25 Mar, 2022
- 1 location
Magnesium Infusion for Pain Management in Critically Ill Trauma Patients
Magnesium is a naturally occurring mineral that is important for your body and brain. Magnesium sulfate (study drug) is a medication containing magnesium that is commonly used to improve low blood levels of magnesium. Magnesium sulfate has also proven to be successful in managing pain before and after surgery. However, …
- 41 views
- 29 Jul, 2023
- 1 location
ANgiogenic Function at NOrmal TErm on Placenta (ANNOTEP)
In vivo and ex vivo study of trophoblastic angiogenic trophoblastic function in placentas from normal pregnancies, at term
- 13 views
- 09 Feb, 2022
- 1 location