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Found 95 clinical trials
sFlt1/PlGF and Selective Labor Induction to Prevent Preeclampsia at Term (PE37)

Preeclampsia (PE) affects ~5% of pregnancies. Although improved obstetrical care has significantly diminished associated maternal mortality, PE remains a leading cause of maternal

cesarean section
prenatal
Accepts healthy volunteers
  • 0 views
  • 16 May, 2022
  • 12 locations
Impact of First-trimester Preeclampsia Screening on Perinatal and Maternal Morbidity (RANSPRE) (RANSPRE)

The purpose of this study is to determine whether first-trimester screening for preeclampsia based on the FMF algorithm (a combination of maternal clinical, sonographic and biochemical

  • 0 views
  • 09 Apr, 2023
Natural Versus Programmed Frozen Embryo Transfer (NatPro) (NatPro)

NatPro is a two-arm, parallel-group, multi-center, randomized trial in which women undergoing frozen embryo transfer (FET) will be randomized to receive either a modified natural cycle (corpus luteum present) or a programmed cycle (corpus luteum absent).

diabetes
Accepts healthy volunteers
progesterone
body mass index
  • 24 views
  • 04 Oct, 2022
  • 8 locations
Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy (SLEEP)

A randomized controlled trial of 1,500 women to assess whether treatment of obstructive sleep apnea with continuous positive airway pressure (CPAP) in pregnancy will result in a reduction in the rate of hypertensive disorders of pregnancy.

  • 273 views
  • 17 Sep, 2023
  • 11 locations
Disitamab Vedotin With Pembrolizumab vs Chemotherapy in Previously Untreated Urothelial Cancer Expressing HER2

This study will enroll participants with urothelial cancer (UC). UC can include cancer of the bladder, kidney, or the tubes that carry pee through the body (ureter, urethra). This study will try

  • 0 views
  • 12 Sep, 2023
  • 10 locations
Chronotherapy With Low-dose Aspirin for Primary Prevention (CARING)

women at high risk for preeclampsia and a fourth one in previously untreated patients with mild hypertension. The findings of these BP studies are consistent; BP-lowering effect of low-dose ASA is

metabolic syndrome
hypertension
type 2 diabetes mellitus
Accepts healthy volunteers
aspirin
  • 21 views
  • 23 Jan, 2022
  • 19 locations
HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children

pregnant women significantly less often suffer from, among others, gestational diabetes, excessive weight gain, lipids disorders, hypertension, preeclampsia, depressive symptoms, functional and structural

infertility
preterm delivery
hypertension
depressive symptoms
prenatal
  • 0 views
  • 22 Aug, 2021
  • 1 location
Predictors of Aspirin Failure in Preeclampsia Prevention

Hypertensive disorders of pregnancy (including preeclampsia) are among the leading causes of pregnancy complications and maternal deaths worldwide. They also increase the risks to the babies

Accepts healthy volunteers
  • 0 views
  • 07 Apr, 2023
  • 1 location
Low Doses of Aspirin in the Prevention of Preeclampsia (ASAPP)

Preeclampsia (PE) is a morbid and potentially lethal complication of pregnancy and is more common in women with specific risk factors. Aspirin (ASA) is currently the only prophylactic therapy

hypertension
Accepts healthy volunteers
pregnancy complication
nephropathy
aspirin 81 mg
  • 90 views
  • 18 Feb, 2022
  • 1 location
ASA Patterns for Prevention of Preeclampsia in SLE Pregnancies

Preeclampsia is a serious maternal condition affecting up to 5% of pregnancies from the general population and up to 30% of lupus pregnancies. Aspirin (acetylsalicylic acid- ASA) has been shown

aspirin
lupus
  • 65 views
  • 14 Jul, 2022
  • 2 locations