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Found 77 clinical trials
Polymorphisms and Busulfan Pharmacokinetic Study

Test the correlations between the pharmacogenetic and pharmacokinetic of Busulfan IV in children receiving hematopoietic stem cell transplantation.

  • 02 Feb, 2022
  • 2 locations
Follow-up of mTBI Patients Discharged From the ED Using Standard Clinical Triage Including BrainScope One (MEDO)

The purpose of the study is to validate the clinical outcome in patients with closed head injuries (GCS 14-15, ages 18-85) who are being evaluated for head trauma, integrating the BrainScope One structural injury classifier (SIC) algorithm, with focus on SIC negative classification. In addition, to assess functional impairment (concussion) …

closed head injuries
post-concussion syndrome
head injury
  • 04 Oct, 2022
  • 7 locations
Longitudinal Cognitive Assessment by BoCA (BoCA)

The Boston Cognitive Assessment (BoCA) is a self-administered online test intended for longitudinal cognitive monitoring. BoCA uses random not-repeating tasks to minimize learning effects. BoCA was developed to evaluate the effects of treatment in longitudinal clinical trials and available gratis to individuals and professionals.

Accepts healthy volunteers
cognitive assessment
  • 26 Jan, 2022
  • 1 location
Long-Term Evaluation and Follow Up Care of Patients Treated With Allogeneic Stem Cell Transplants

This study will provide follow-up evaluation and care of patients who have undergone allogeneic (donor) stem cell transplantation at the NIH Clinical Center. Patients are monitored for their response to treatment, disease relapse, and later-occurring effects of the transplant. Patients between 10 and 80 years of age who received a …

cell transplantation
computerized tomography
multiple gated acquisition scan
Accepts healthy volunteers
stem cell transplantation
  • 28 Oct, 2022
  • 1 location
Studying Radiation Doses in Patients Undergoing Stem Cell Transplant Treated With Total-Body Irradiation

treatment. PURPOSE: This research study is evaluating radiation doses in patients undergoing stem cell transplant treated with total-body irradiation.

  • 07 Nov, 2020
  • 1 location
Biomarkers in the Brain Oxygen Optimization in Severe Traumatic Brain Injury Trial (BioBOOST)

BioBOOST is a multicenter, observational study of the effect of derangements in brain physiologic parameters on brain injury biomarker levels in patients with severe traumatic brain injury.

traumatic brain injury
severe traumatic brain injury
  • 22 Mar, 2022
  • 1 location
Adding Azathioprine/Hydroxyurea Preconditioning to Alemtuzumab/TBI to Reduce Risk of Graft Failure in MSD HSCT in Adult SCD Patients

In this study the investigators will prospectively investigate whether the addition of a 3-months long preconditioning with azathioprine to the alemtuzumab/TBI non-myeloablative conditioning results in improved disease-free survival and donor chimerism after allo-SCT in SCD patients. Furthermore, the investigators will evaluate whether azathioprine/hydroxyurea preconditioning leads to more patients being able …

cell transplantation
  • 15 Mar, 2022
  • 1 location