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Found 54 clinical trials
Featured trial
  • 114 views
  • 08 Nov, 2020
  • 1 location
The Combination of Immunotherapy and Neoadjuvant Short-course Radiotherapy in Locally Advanced Rectal Cancer (TORCH)

oxaliplatin (CAPOX) chemotherapy and PD-1 antibody, finally receive the total mesorectal excision (TME). Induction cohort: A total of 65 patients will firstly receive 2 cycles of CAPOX chemotherapy and PD-1

  • 0 views
  • 04 Oct, 2022
  • 4 locations
Short-course Radiotherapy Followed by Tislelizumab + CapeOX in the Treatment for Locally Advanced Rectal Cancer

This study is a single-center, prospective, open-label, randomized controlled clinical study, and the purpose of this study was to compare the pathological complete response rate (PCR) of patients with locally advanced rectal cancer treated with short-course radiotherapy sequential Tislelizumab combined with CapeOX (group A) versus short-course radiotherapy sequential CapeOX (group …

  • 0 views
  • 04 Oct, 2022
  • 1 location
A Trial of Neoadjuvant mFOLFOXIRI Versus CRT in the EMVI Positive LARC

Extramural Vascular Invasion Positive(EMVI+) is a high risk of distant metastasis for locally advanced rectal cancer(LARC) after resection. The study is to evaluate the efficacy and safety of FOLFOXIRI as neoadjuvant chemotherapy alone for EMVI+ LARC in contrast to the efficacy of standard Chemoradiotherapy (CRT).

  • 0 views
  • 30 Mar, 2021
  • 1 location
Transanal Versus Laparoscopic Total Mesorectal Excision For Rectal Cancer

morbidity and unsatisfactory resection quality, especially in challenging cases such as bulky mesorectum, enlarged prostate, irradiated pelvis, etc. Under this circumstance, transanal total mesorectal

metastasis
open surgery
cancer
adjuvant therapy
rectal carcinoma
  • 15 views
  • 10 Feb, 2022
  • 17 locations
Preoperative FOLFOX Versus Postoperative Risk-adapted Chemotherapy in Patients With Locally Advanced Rectal Cancer

This is a multicenter, prospective, randomized, stratified, controlled, open-label study comparing preoperative FOLFOX versus postoperative risk-adapted chemotherapy in patients with locally advanced rectal cancer and low risk for local failure

folfox regimen
adenocarcinoma
capecitabine
xelox
oxaliplatin
  • 0 views
  • 04 Oct, 2022
  • 1 location
Clinical Database of Colorectal Robotic Surgery (ROBOT CR)

Evaluation of robot Da Vinci Xi by determining its learning curve.The operating time will be defined by patient then the operating average will be calculated.

colitis
colorectal neoplasm
ulceration
crohn's disease
ulcerative colitis
  • 1 views
  • 12 Feb, 2022
  • 4 locations
Low or High Ligation of the IMA With Apical Lymph Node Dissection in Rectal Cancer Laparoscopic Surgery

Laparoscopy colon surgery is accepted worldwide in the recent years. But there is still argument on the effect of laparoscopy rectal surgery. Laparoscopy has advantages on showing the inferior mesenteric artery (IMA), protection of autonomic nerve, low rectal anastomosis, and total mesorectum excision. However, debate on the level of IMA …

general anesthesia
metastasis
adenocarcinoma
rectal anastomosis
fluorouracil
  • 0 views
  • 25 Feb, 2022
  • 1 location
Transanal Versus Laparoscopic Total Mesorectal Excision for Rectal Cancer. (taTME)

This study is designed as a prospective, multi-center, randomized, open-labelled, parallel group, non-inferiority trial. The aim of this study is to evaluate the TaTME technique compared with conventional laparoscopic rectal surgery, focusing on, anastomotic dehiscence, conversion rate to open surgery, hospital stay and long-term functional outcomes.

metastasis
open surgery
pelvic mri
total mesorectal excision
digital rectal examination
  • 0 views
  • 12 Feb, 2022
  • 1 location
Transanal Total Mesorectal Excision Versus Laparoscopic TME for Rectal Cancer

To investigates the feasibility, practicability, safety and subjective as well as functional outcome of transanal minimal invasive surgery toal mesentery excision for rectal cancer.

adenocarcinoma of rectum
adenocarcinoma
pelvic mri
cancer
low anterior resection
  • 0 views
  • 13 May, 2022
  • 1 location