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Found 82 clinical trials
Italian Digital Primary Cardiovascular Prevention Study (CV-PREVITAL)

The CV-PREVITAL study is a randomised clinical trial (RCT) controlled versus usual-care designed to compare the effectiveness of a mobile health (mHealth) intervention with that of usual care in reducing specific cardiovascular (CV) risk factors (in the short term) and the occurrence of vascular events (in the long term). Promoted …

Accepts healthy volunteers
  • 0 views
  • 27 Jul, 2022
  • 29 locations
Effect of Dietary Protein on the Regulation of Exosome microRNA Expression in Patients With Insulin Resistance.

and food logs, biochemical tests (insulin, glucose, triglycerides, total cholesterol, HDL, LDL), the relative expression of plasma exosome miRNAs and markers of oxidative stress will be evaluated

  • 0 views
  • 26 Apr, 2022
  • 2 locations
HYPOCHOL : A Genetically-based Strategy to Identify New Targets in Cholesterol Metabolism (HYPOCHOL)

The aim of this study is to identify new targets in cholesterol metabolism thanks to a genetically-based strategy.

  • 0 views
  • 24 Feb, 2022
  • 1 location
Intermitent Hypoxia and Its Pathophysiology Consequences in the Sleep Apnea-Hypopnea Syndrome.

Clinical trial on the effect of continuous positive pressure (CPAP). Objectives: 1) To assess the total or partial recovery of oxidative and inflammatory damage after recovering IH. 2) To check whether the results obtained in vitro on the recovery of the damage according to the form of manifestation of IH …

  • 0 views
  • 31 May, 2021
  • 2 locations
The Effect of Dietary Supplements for Pregnant Women on Levothyroxine Absorption

Hypothyroidism is a common disease that is successfully treated with the replacement of thyroid hormones in the form of levothyroxine. Levothyroxine is drug used in the first line of substitution therapy because it appropriately mimics physiological secretion of thyroxine (T4) and its peripheral conversion to triiodothyronine (T3). However, due to …

  • 0 views
  • 28 Oct, 2021
  • 1 location
Cow Milk Fat Obesity pRevention Trial (CoMFORT)

(glucose, hsCRP, non-HDL, LDL, triglyceride, HDL and total cholesterol, insulin, and diastolic and systolic blood pressure) and sugar sweetened beverage intake (measured by 24-hour dietary recall

insulin
body mass index
nutrition support
Accepts healthy volunteers
  • 7 views
  • 02 Mar, 2022
  • 1 location
Polipill and RiscOMeter to Prevent StrOke and CogniTive ImpairmEnt (PROMOTE) (PROMOTE)

This study is a phase III Randomized Clinical Trial, prospective, placebo controlled of 12,268 subjects with low to moderate risk of stroke followed by 3 years in 60 Primary Health Care Units in Brazil. The units will be randomized (clusters) to use or not the approach of community health workers …

  • 0 views
  • 25 Mar, 2022
Danish Cardiovascular Screening Trial II (DANCAVAS-II)

This study attempts to reduce social inequality in cardiovascular health by performing an interventional screening trial on how best to decrease cardiovascular disease (CVD) among people with low social status.

cardiovascular disease
  • 13 views
  • 06 Feb, 2022
  • 4 locations
Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Group 1)

This exploratory, first-in-man, phase 0 study will evaluate the feasibility of using a sub-therapeutic dose of a fluorine-18 analogue of NP-59 ([18F]FNP-59) to image the adrenal gland in healthy normal subjects. The researchers believe that [18F]FNP-59 would greatly improve the imaging characteristics, by providing a PET imaging cholesterol analogue with …

cholesterol level
Accepts healthy volunteers
  • 0 views
  • 23 Mar, 2022
  • 1 location
Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Groups 2, 3 & 4)

This study will evaluate the feasibility of using a sub-therapeutic dose of a fluorine-18 analogue of NP-59 ([18F]FNP-59) to image the adrenal gland. Some participants are healthy normal subjects but have undergone interventions to manipulate hormones while other participants have known adrenal pathology.

cholesterol level
Accepts healthy volunteers
  • 3 views
  • 21 Mar, 2022
  • 1 location