Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 35 clinical trials
M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers

relapsed SCLC after first-line chemotherapy: topotecan, which inhibits religation of topoisomerase I-mediated single-strand DNA breaks leading to lethal double-strand DNA breaks. Temozolomide, an oral

liver metastasis
oat cell carcinoma
absolute neutrophil count
neutrophil count
topotecan
  • 100 views
  • 19 Jun, 2022
  • 1 location
Testing of Tazemetostat in Combination With Topotecan and Pembrolizumab in Patients With Recurrent Small Cell Lung Cancer

This phase I trial tests the safety, side effects, and best dose of tazemetostat in combination with topotecan and pembrolizumab in treating patients with small cell lung cancer that has come

  • 0 views
  • 29 May, 2022
  • 1 location
Phase 3 Study Evaluating Efficacy Safety and Pharmacokinetics of Trilaciclib In Extensive-Stage Small Cell Lung Cancer Patients Receiving Carboplatin Combined With Etoposide or Topotecan

Receiving Carboplatin combined with Etoposide or Topotecan The study consists of 2 parts: Part 1: safety run-in and pharmacokinetics evaluation of 12 ES-SCLC patients (6 each for first line and second/third

  • 0 views
  • 17 Sep, 2021
  • 1 location
Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer

This phase I trial investigates the side effects and best dose of BAY 1895344 when given together with usual chemotherapy (irinotecan or topotecan) in treating patients with solid tumors that

  • 0 views
  • 16 Jun, 2022
  • 2 locations
Clinical Trial of SP-2577 (Seclidemstat) in Patients With Relapsed or Refractory Ewing or Ewing-related Sarcomas

dose expansion of the combination of seclidemstat with topotecan and cyclophosphamide in patients with Ewing sarcoma

ct scan
liposarcoma
camptothecin
measurable disease
myxoid liposarcoma
  • 83 views
  • 26 Mar, 2022
  • 13 locations
A Study of N9 Chemotherapy in Children With Neuroblastoma

different times - Cyclophosphamide, topotecan, and vincristine (CTV), Ifosfamide, carboplatin, and etoposide (ICE), Cyclophosphamide, doxorubicin, and vincristine (CDV).

carboplatin
doxorubicin
etoposide
cyclophosphamide
topotecan
  • 0 views
  • 02 Jun, 2022
  • 1 location
A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors

/ Paclitaxel, PD1 inhibitors (Nivolumab or Pembrolizumab), and Imiquimod Cream, Bevacizumab, Gemcitabine / Carboplatin / Bevacizumab, Topotecan, and Pegylated liposomal doxorubicin (PLD) for selected advanced

topotecan
ct scan
cancer treatment
5-fluorouracil
carboplatin
  • 20 views
  • 24 Apr, 2022
  • 13 locations
  • 0 views
  • 20 Jun, 2022
  • 2 locations
Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors

This study will evaluate palbociclib in combination with chemotherapy (temozolomide with irinotecan and/or topotecan with cyclophosphamide) in children, adolescents and young adults with

biological factors
central nervous system tumor
kidney function test
renal function
temozolomide
  • 129 views
  • 09 Jun, 2022
  • 56 locations
Evaluation of TRILACICLIB in Chinese Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC) for Chemotherapy-induced Myelosuppression Antitumor Effects of Combination Regimens and Safety in a Real-world Study

already use or plan to use Trilaciclib will be invited to participate in the study. Data were collected from 28 days prior to initial chemotherapy (platinum/etoposide or topotecan systemic chemotherapy

  • 0 views
  • 17 Oct, 2021
  • 1 location