Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 36 clinical trials
featured
AEWS1031: A Phase III Randomized Trial of Adding Vincristine-Topotecan-Cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-Metastatic Ewing Sarcoma

AEWS1031: A Phase III Randomized Trial of Adding Vincristine-Topotecan-Cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-Metastatic Ewing Sarcoma

  • 376 views
  • 08 Nov, 2020
  • 1 location
Combination Chemotherapy in Treating Young Patients With Nonmetastatic Rhabdomyosarcoma

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. It is not yet known which combination chemotherapy regimen is more …

doxorubicin
cancer chemotherapy
carboplatin
combination chemotherapy
tumor cells
  • 103 views
  • 07 Nov, 2020
  • 9 locations
Observation Combination Chemotherapy Radiation Therapy and/or Autologous Stem Cell Transplant in Treating Young Patients With Neuroblastoma

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving combination chemotherapy may kill more tumor cells. Radiation therapy uses high-energy x-rays to kill tumor cells. An autologous stem cell transplant may …

doxorubicin
topotecan
carboplatin
melphalan
combination chemotherapy
  • 30 views
  • 07 Nov, 2020
  • 28 locations
Topotecan Episcleral Plaque for Treatment of Retinoblastoma

This single site, single-arm, non-randomized, dose escalation phase I toxicity clinical trial will assess primarily the safety and secondarily the efficacy of episcleral topotecan in patients

renal function
platelet count
topotecan
intraocular retinoblastoma
  • 2 views
  • 29 May, 2021
  • 1 location
A Study of FF-10850 Topotecan Liposome Injection in Advanced Solid Tumors

To determine the safety profile, maximum tolerated dose (MTD), dose-limiting toxicities (DLTs), and recommended Phase 2 dose (RP2D) of FF-10850 (topotecan liposome injection) in patients with

  • 0 views
  • 25 Jan, 2021
  • 3 locations
Clinical Trial of SP-2577 (Seclidemstat) in Patients With Relapsed or Refractory Ewing or Ewing-related Sarcomas

dose expansion of the combination of seclidemstat with topotecan and cyclophosphamide in patients with Ewing sarcoma

camptothecin
ct scan
measurable disease
refractory ewing sarcoma
  • 75 views
  • 27 Apr, 2021
  • 9 locations
Ocular Conservative Treatment for Retinoblastoma : Efficacy of the New Management Strategies and Visual Outcome

randomized phase-II study evaluating the efficacy of Intra-Arterial Chemotherapy (IAC) with melphalan and topotecan versus melphalan alone, both in association with ophthalmologic treatments. Study

  • 0 views
  • 13 Apr, 2021
  • 28 locations
Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma

intraocular retinoblastoma (Stratum B) to two upfront courses of therapy consisting of subconjunctival carboplatin and systemic topotecan. SECONDARY OBJECTIVES: To

doxorubicin
topotecan
carboplatin
filgrastim
renal function
  • 43 views
  • 04 Feb, 2021
  • 1 location
A Phase I/II Study of Paclitaxel Plus Carboplatin Plus Vorinostat in Recurrent Ovarian Cancer

consists of systemic chemotherapy using either carboplatin plus paclitaxel (in platinum-sensitive patients) or single agent chemotherapy with agents like liposomal doxorubicin, topotecan, weekly

ovarian epithelial cancer
doxorubicin
carcinoma
recurrent ovarian cancer
carboplatin
  • 10 views
  • 07 Nov, 2020
  • 1 location
Treatment Protocol for Non-Metastatic Unilateral Retinoblastoma

This protocol provides guidelines for the management of non-metastatic unilateral retinoblastoma and introduces an innovative adjuvant therapy for higher risk patients based upon the results of the Grupo de America Latina de Oncologia Pediatrica (GALOP) I study. Conservative therapy will be not protocolized.

  • 48 views
  • 23 Jan, 2021
  • 1 location