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Found 57 clinical trials
Sensor-Dot and Plug 'n Patch Study in Epilepsy

The investigators plan to determine whether it is possible to use a small, unobtrusive wearable device (the Sensor Dot with Plug 'n Patch system) to follow-up epilepsy in the home environment through measurement of different biosignals (EEG, ECG, EMG, motion, skin temperature, respiration and oxygen saturation) for prolonged periods in …

epileptic syndromes
tonic
seizure
generalized epilepsy
  • 0 views
  • 07 Jun, 2022
  • 1 location
Snacks and Satiety

This study is designed to compare two types of snacks (almonds or a cereal-based snack), eaten between meals, on measures of appetite, including appetitive hormones, self-reported feelings of hunger and fullness, and food intake at a buffet meal or in the home environment. The investigators hypothesize that the acute responses …

body mass index
Accepts healthy volunteers
hunger
  • 277 views
  • 23 Mar, 2022
  • 1 location
Distal Renal Denervation to Prevent Renal Function Decline in Patients With T2DM and Hypertension

The aim of this study is to test the hypothesis that distal renal denervation (RDN) may delay or prevent the progressive decline of renal function in patients with type 2 diabetes mellitus and hypertension

type 2 diabetes mellitus
kidney function tests
hypertension
diabetes
glucose tolerance test
  • 1 views
  • 09 Jul, 2021
  • 1 location
Neural Mechanisms of Immersive Virtual Reality in Chronic Pain

This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.

chronic pain
pain relieving
  • 0 views
  • 11 May, 2022
  • 1 location
Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy

This is a multiple site, randomized, double blinded parallel-group controlled study. The purpose of this study is to evaluate efficacy, safety, and tolerability of repeated, daily sessions with the STARSTIM device, which delivers transcranial cathodal direct current stimulation (tDCS). Subjects will be treated with STARTSTIM or sham device for 10 …

antiepileptics
seizure
tonic
electroencephalogram
  • 0 views
  • 27 Jun, 2022
  • 6 locations
Aging and Cortical Excitability (ACE)

The objective of the current proposal is to identify 1) how aging-related changes in GABAergic cortical inhibition affect motor performance, and 2) how aerobic exercise may improve inhibitory function and facilitate motor learning.

balance training
aerobic exercise
Accepts healthy volunteers
  • 49 views
  • 28 Jun, 2022
  • 1 location
Transspinal Stimulation Plus Locomotor Training for SCI

Locomotor training is often used with the aim to improve corticospinal function and walking ability in individuals with Spinal Cord Injury. Excitingly, the benefits of locomotor training may be augmented by noninvasive electrical stimulation of the spinal cord and enhance motor recovery at SCI. This study will compare the effects …

electrical stimulation
spinal cord disorder
gait training
locomotor training
spinal cord
  • 0 views
  • 19 Jun, 2022
  • 2 locations
Acute Alcohol Response In Bipolar Disorder: a fMRI Study (BACS)

Alcohol use disorders (AUDs) affect up to 60% of individuals with bipolar disorder during their lifetime-a rate 3 to 5 times higher than what occurs in the general population. The mechanisms that contribute to elevated rates of comorbidity are not known. Early identification in individuals with bipolar disorder who are …

Accepts healthy volunteers
  • 53 views
  • 22 Mar, 2022
  • 1 location
Spinal Cord Stimulation and Respiration After Injury

Respiratory motor control deficit is the leading cause of morbidity and mortality in patients with spinal cord injury. The long-term goal of this NIH-funded study is to develop a rehabilitation strategy for respiration in patients with spinal cord injury as a standard of care. Respiratory function in patients with chronic …

spinal cord
spinal cord disorder
spinal cord stimulation
deficit
  • 0 views
  • 23 Mar, 2022
  • 1 location
Examining the Effects of Estradiol on Neural and Molecular Response to Reward (PEEPS)

This proposal will examine the effects of estradiol administration on perimenopausal-onset (PO) anhedonia and psychosis symptoms as well as on brain function using simultaneous positron emission tomography and functional magnetic resonance imaging (PET-MR).

  • 0 views
  • 29 Apr, 2022
  • 1 location