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Found 55 clinical trials
Silver Diamine Fluoride in Preventing Occlusal Caries in Primary Teeth

% SDF; Group B - semi-annual application of 5% NaF varnish; and Group C - semi-annual application of placebo control with tonic water. Clinical examination of the study teeth in the children will be

Accepts healthy volunteers
  • 24 Oct, 2021
  • 1 location
Randomized, Double-Blind Study to Evaluate Efficacy and Safety of Cenobamate Adjunctive Therapy in PGTC Seizures

This trial is intended to study the safety and effectiveness of an new anti-epileptic drug (AED) on Primary Generalized Tonic-Clonic (PGTC) Seizures. Eligible Subjects will continue to take

  • 03 Jun, 2022
  • 6 locations
Is Low Level Laser Therapy (LLLT) Effective for Reducing Pain Experienced by Women With Provoked Vestibulodynia?

-reported pain and sexual functioning, physiological responses to pressure applied at the vulvar vestibule, tonic and phasic activation of the PFM and/or corticomotor excitability to the PFMs in women with

  • 10 Oct, 2021
  • 1 location
Comparison of Muscle Energy Technique and Eccentric Training on Hamstring Flexibility in Healthy Young Adults

Flexibility is the ability of a muscle to lengthen and allow one joint (or more than one joint in series) to move through a full range of motion (ROM).Adequate flexibility is important to maintain balance, agility and musculoskeletal function. A decrease in muscular flexibility does not only reduces functional level …

Accepts healthy volunteers
  • 04 Oct, 2022
Freedom-1 Study for Chronic Knee Pain

To demonstrate the potential benefits and risk of active sub-threshold stimulation in the treatment of chronic knee pain as compared to subjects that did not have active stimulation. Improvement will be assessed in relation to the clinical outcome measures of pain, with primary endpoint; Pain relief rate as measured by …

  • 04 Oct, 2022
  • 8 locations
Prevention of Epilepsy by Reducing Neonatal Encephalopathy (PREVENT)

The aim of the study is to examine if a pragmatic, evidenced based and generalisable intrapartum care bundle involving birth companions and empowering mothers will reduce birth injury-related epilepsy at 18 months of age in India. The care bundle will have four key elements (interventions): (1) birth companion providing constant …

  • 07 Jun, 2022
  • 3 locations
Comparison of Effectiveness of Tonic, High Frequency and Burst Spinal Cord Stimulation in Chronic Pain Syndromes

parestesias and in other three they would not. Patients are not informed that beside tonic, burst and high frequency stimulation, the fourth is an off stimulation to check for placebo effect. The test is

pain disorder
chronic pain
  • 08 Feb, 2022
  • 1 location
Investigate the Efficacy and Safety of Carisbamate (YKP509) as Adjunctive Treatment for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults

The primary objective is to evaluate the efficacy of carisbamate (YKP509) as adjunctive treatment in reducing the number of drop seizures (tonic, atonic, and tonic-clonic) compared with placebo

  • 07 Oct, 2022
  • 1 location
A Study to Investigate the Efficacy and Safety of ZX008 in Subjects With CDKL5 Deficiency Disorder

This is a multicenter, double-blind, parallel-group, placebo controlled, 2-part study to evaluate the efficacy and safety of ZX008 when used as adjunctive therapy for the treatment of uncontrolled seizures in children and adults with cyclin-dependent kinase like-5 (CDKL5) deficiency disorder (CDD).

  • 04 Oct, 2022
  • 3 locations
RNS® System Responsive Thalamic Stimulation for Primary Generalized Seizures (NAUTILUS) Study (NAUTILUS)

To demonstrate that the RNS System for thalamic stimulation is safe and effective as an adjunctive therapy for the reduction of primary generalized seizures in individuals 12 years of age or older who have drug-resistant idiopathic generalized epilepsy.

  • 12 Oct, 2022
  • 2 locations