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Found 138 clinical trials
Sucrose-sweetened Beverage in African-American and Caucasian Women. (SAAC)

The main objective of this pilot study is to measure changes in metabolic risk factors of cardiovascular disease and type 2 diabetes in response to sugar-sweetened beverages in African-American and non-Hispanic white women.

Accepts healthy volunteers
  • 168 views
  • 22 Mar, 2022
  • 2 locations
Effect of Gender Affirming Hormone Therapy on Glucose Metabolism

The study will test: whether estrogen treatment in transwomen is associated with improved insulin sensitivity and beta cell function whether testosterone treatment in transmen is associated with worsening insulin sensitivity and beta cell function whether estrogen therapy leads to enhanced immune response in older transwormen

Accepts healthy volunteers
  • 24 views
  • 23 Mar, 2022
  • 1 location
The Role of GIP and GLP-2 in Postprandial Splanchnic Blood Flow Distribution and Metabolism (GA-17)

This project will describe the mechanisms of action and the relative contributions of GIP and GLP-2 to changes in gastrointestinal blood flow induced by oral glucose, exogenous GIP and GLP-2 infusions, and endogenous GIP and GLP-2 with the use of two novel receptor antagonists GIP(3-30)NH2 and GLP-2(3-33) in healthy individuals.

Accepts healthy volunteers
  • 0 views
  • 05 Jun, 2022
  • 1 location
Modulating the GIP System in Patients With Acromegaly Due to a Pituitary Tumor (GA-9)

Modulation of the GIP System in Patients With Acromegaly Due to a Pituitary adenoma

  • 11 views
  • 15 Feb, 2022
  • 1 location
Immune Cells During Disuse and Recovery

This is an interventional study enrolling healthy individuals aged 18-35 and 60-85 to understand the recovery of muscle health following a period of inactivity. The enrollment goal is 45 participants. The study will occur over the course of 1-2 months where participants will undergo testing before and after a 2-week …

Accepts healthy volunteers
  • 1 views
  • 14 Jul, 2022
  • 1 location
Tacrolimus Formulation and Glucose Metabolism After Kidney Transplantation (TAGLUMET Trial) (TAGLUMET)

Posttransplantation diabetes mellitus after kidney transplantation mediated by tacrolimus is mainly dependent on dose and peak plasma concentration. To substantiate the potential benefits on glucose metabolism and lipid profile of LCP-tacrolimus compared to standard twice-daily tacrolimus after kidney transplantation, a prospective randomized intraindividual cross-over conversion trial with a comprehensive assessment …

  • 0 views
  • 09 Jul, 2022
  • 1 location
Effect of Dietary Protein on the Regulation of Exosome microRNA Expression in Patients With Insulin Resistance.

miRNAs are small non-coding RNAs of approximately 22 nucleotides in length, which have the function of regulating gene expression at the post-transcriptional level through base complementation of protein-coding transcripts, this interaction leading to translational repression by destabilizing the messenger RNA. Evidence demonstrates an association between differences in miRNA expression and …

  • 0 views
  • 26 Apr, 2022
  • 2 locations
Importance of Blood Volume and Its Interaction With Cardiovascular Adaptations

The present project aims to investigate the interaction between training-induced blood volume expansion (plasma- and red blood cell volume responses), central as well as peripheral cardio-vascular adaptations. We will investigate cardiovascular responses through one year of training in recreationally active men and women as well as endurance athletes undertaking shorter …

Accepts healthy volunteers
  • 0 views
  • 04 Jun, 2022
  • 2 locations
Effectiveness of CGMS vs. Self-monitoring Blood Glucose (SMBG) in Woman With Gestational Diabetes

The detection of and control of gestational diabetes carries benefits for both mother and baby related to immediate pregnancy outcomes. The glycemic disorders in diabetes are not solely limited to fasting and postprandial hyperglycemia, but can be extended to the glycemic variability that includes both upward (postprandial glucose increments) and …

  • 0 views
  • 29 Oct, 2021
  • 1 location
VLCD & Adjuvant Exercise Effect in Overweight Diabetic Men (VLCDeXDM)

Sarcopenia is defined as the incremental age-related loss of skeletal muscle in humans which generally begins from forty years old. It is associated with an overall reduction in quality of life and increased morbidity and mortality. Patients with type two diabetes mellitus (T2DM) are particularly at risk of developing sarcopenia, …

  • 0 views
  • 26 Jul, 2022
  • 1 location