Found 41 clinical trials
Effect of Tofacitinib on Coagulation and Platelet Function, and Its Role in Thromboembolic Events
(tofacitinib) will be initiated by clinical practice and the choice will be made at the discretion of the investigator at the center where the patients will be recruited (Hospital Universitario de La Princesa
- 0 views
- 04 Oct, 2022
- 1 location
Evaluation of Pain Sensitization in Rheumatoid Arthritis: Analysis on a Cohort of Tofacitinib Treated Patients (TOPRA)
implicated in the pathophysiology of RA, such as IL-6, IL-12, IL-23 and IFNs. Two Jak-inhibitors have been put on the market: Tofacitinib and Baricitinib. In randomized clinical trials, Tofacitinib have
- 1 views
- 11 Feb, 2022
- 1 location
Open-label Study of Tofacitinib for Moderate to Severe Skin Involvement in Young Adults With Lupus
This 76-week, 3-part Phase 1b/2 study is intended to evaluate the pharmacological properties (pharmacokinetics and pharmacodynamics), safety, tolerability and preliminary effectiveness of TOFA administrated to young adults (18-45 years) with moderately to severely active SLE-CL. Subjects will be studied at the Cincinnati Children's Hospital Medical Center (CCHMC) and in Cleveland …
- 72 views
- 04 Oct, 2022
- 2 locations
The Immunogenicity and Safety of Shingrix Vaccine in Patients With Moderate to Severe Ulcerative Colitis on Tofacitinib
contain live HZ virus. Data on efficacy of the Shingrix vaccine also appears promising in immunocompromised patients. Tofacitinib citrate (Xeljanz), an immunosuppressant that works by inhibiting
- 49 views
- 12 Oct, 2022
- 1 location
An Open-label Study of Tofacitinib for the Treatment of Refractory Immune-related Colitis From checKpoint Inhibitor Therapy (TRICK)
This is a single-arm pilot study evaluating the efficacy and safety of tofacitinib in cancer patients with immune-related colitis from immune checkpoint inhibitor (ICI) therapy.
- 0 views
- 28 Oct, 2022
- 1 location
Impact of Anti-TNF Vedolizumab and Tofacitinib on Aortic Stiffness Carotid Intima-media Thickness and Cardiovascular Risk of Patients With Ulcerative Colitis
12 months of anti-TNF, vedolizumab and tofacitinib.
- 0 views
- 18 Jul, 2021
- 1 location
Second Line Induction Therapy and Healthy Diet for Patients With Ulcerative Colitis
The purpose of this study is to determine whether a diet intervention (the Fasting Mimicking diet) will help induce clinical and biochemical response to tofacitinib therapy or second line
- 0 views
- 14 May, 2022
- 1 location
Examination of Efficacy and Safety of Baricitinib in RA Patients
>Biologics treatment for 12 months Tofacitinib treatment for 12 months
- 4 views
- 01 Feb, 2022
- 1 location
Baricitinib for the Treatment of Ocular Mucous Membrane Pemphigoid
) inhibition with baricitinib or tofacitinib been reported to be successful in one case of ocular MMP. This is a randomized, single-masked, two-arm study of baricitinib vs anti-proliferatives for
- 0 views
- 17 Mar, 2022
A Pilot Study in Severe Patients With Takayasu Arteritis.
Takayasu arteritis (TAK) is a rare chronic inflammatory arteritis, which lacks an effective well-accepted intervention strategy. We classify TAK patients into 3 levels, including mild, moderate, and severe. And the biological agents tocilizumab and adalimumab are randomly prescribed in severe patients, to find out the relatively better treatment strategy, facilitating …
- 0 views
- 01 Mar, 2022
- 1 location