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Found 41 clinical trials
Comparison of Tofacitinib and Methotrexate in Takayasu's Arteritis

The aim of this study is to evaluate and compare the efficacy and safety of tofacitinib and methotrexate based on prednisone therapy in patients with Takayasu arteritis

  • 0 views
  • 10 Nov, 2021
  • 1 location
Tofacitinib: Suppressing Tumor Invasion in Recurrent GBM Patients

The purpose of this study is to examine the effects of Tofacitinib in patients with recurrent Glioblastoma.

  • 0 views
  • 27 Oct, 2022
  • 1 location
Tofacitinib for Immune Skin Conditions in Down Syndrome

interferon (IFN) signaling seen in DS is safe and could improve associated skin conditions. The study evaluates the safety and efficacy treatment with Tofacitinib, an FDA-approved drug known to block

mediators
alopecia areata
atopy
skin disorder
hidradenitis
  • 88 views
  • 04 Oct, 2022
  • 1 location
Efficiency of Methotrexate and Tofacitinib in Mild and Moderate Patients

mild, moderate, and severe, and prescribe methotrexate and tofacitinib randomly in mild and moderate patients, to observe the relatively better treatment strategy, facilitating better intervention

tofacitinib
methotrexate
  • 4 views
  • 01 Mar, 2022
  • 1 location
Effects of Tofacitinib vs Methotrexate on Rheumatoid Arthritis Interstitial Lung Disease (PULMORA)

data indicate that inhibition of Janus kinase is beneficial for this extra-articular manifestation. Our goal is to determine whether tofacitinib is an effective and safe treatment, compared to standard

tofacitinib
prednisone
antirheumatics
interstitial lung disease
methotrexate
  • 1 views
  • 10 May, 2022
  • 1 location
Comparison of Tofacitinib and Methotrexate in the Maintained Treatment of GPA

The aim of this study is to identify the optimal maintenance therapy for granulomatosis with polyangiitis (GPA) by comparing the MTX (standard regimen) with Tofacitinib in terms of efficacy, i.e

  • 0 views
  • 16 Jul, 2021
  • 1 location
Tofacitinib in the Treatment of Rheumatoid Arthritis-related Interstitial Lung Disease. (RAILDTo)

. There is preliminary data that tofacitinib may have a beneficial effect in treating RA-ILD. Tofacitinib may have a double role in treating RA-ILD: treat RA disease activity and an anti-fibrotic possible

prednisone
rituximab
lung biopsy
pneumonia
azathioprine
  • 0 views
  • 18 Apr, 2022
Comparison of Adalimumab and Tofacitinib in the Treatment of Active Takayasu Arteritis (ADATOFTAK)

This is a prospective,open-labelled,multi-center,randomized clinical trial.It compares the clinical efficacy and safety of there 2 drugs in the treatment of relapse active Takayasu's arteritis patients.

  • 0 views
  • 12 Mar, 2022
  • 1 location
Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren's Syndrome

of tofacitinib in people with SS. Eligibility Adults ages 18-75 with SS. Design Participants will be screened on a separate

tofacitinib
hydroxychloroquine
glucocorticoids
chloroquine
autoimmune disease
  • 2 views
  • 06 Apr, 2023
  • 1 location
Efficacy, Safety and Immunological Evaluation of Tofacitinib in the Treatment of Primary Sjogren's Syndrome

This study aims to explore the clinical and immunological efficacy of tofacitinib on primary Sjögren's Syndrome

  • 0 views
  • 08 Mar, 2022
  • 1 location