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Found 45 clinical trials
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A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects With Moderately to Severely Active Ulcerative Colitis

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects With Moderately to Severely Active Ulcerative Colitis

  • 290 views
  • 25 Mar, 2021
  • 1 location
A Safety, Efficacy And Pharmacokinetics Study Of Tofacitinib In Pediatric Patients With sJIA

A randomized withdrawal study in which responders to open-label treatment with tofacitinib will be randomized in a 1:1 ratio to tofacitinib or placebo in a double-blind phase. In the double

  • 134 views
  • 16 May, 2022
  • 39 locations
The Role of Tofacitinib in Steroid Withdrawal in Rheumatoid Arthritis

treatment of RA, tofacitinib can relieve RA symptoms and promote joint healing It can recover the injury and correct the abnormal immune function. At present, studies have proved that the traditional anti

antirheumatics
stiffness
synovitis
DMARD
tofacitinib
  • 8 views
  • 22 Jun, 2021
  • 1 location
Tofacitinib for Hospitalized Acute Severe Ulcerative Colitis Management

The TRIUMPH study was designed to build on the existing literature by studying the efficacy of tofacitinib in hospitalized patients with acute severe ulcerative colitis. This trial will provide

  • 0 views
  • 24 Jun, 2021
  • 1 location
The Efficacy and Safety of Tofacitinib (TF) With Iguratimod (IGU) on RA

disability. Tofacitinib(TF) is a new type of oral tyrosine kinase inhibitor (JAKi) for the treatment of moderate to severe active RA. However, there is alack of Chinese data on the joint scheme, long-term

autoimmune disease
tofacitinib
  • 0 views
  • 26 Jun, 2021
  • 1 location
The Safety and Efficacy of TLL-018 in Active Rheumatoid Arthritis

This is a randomized, double-blind, double-dummy, tofacitinib-parallel-group, phase 2A study to assess the safety and efficacy of TLL-018 in active rheumatoid arthritis subject who had an

hydroxychloroquine
leflunomide
methotrexate
rheumatoid factor
sulfasalazine
  • 0 views
  • 25 Apr, 2022
  • 1 location
Combination of Baricitinib and Adalimumab in Rheumatoid Arthritis (CRI-RA)

, combination of tofacitinib (which belongs to the same Jaki family as baricitinib) with various biologics has been reported in a sample of RA patients. No serious adverse effects were reported over a mean of

rituximab
tumour necrosis
methotrexate
abatacept
anakinra
  • 0 views
  • 15 Mar, 2022
  • 6 locations
Long-Term Safety Study Of Tofacitinib In Patients With Juvenile Idiopathic Arthritis

Evaluate long-term safety and tolerability of tofacitinib in patients with JIA, who have previously participated in tofacitinib JIA studies.

arthritis
DMARD
treatment regimen
  • 319 views
  • 17 May, 2022
  • 45 locations
Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis

This study, A3921210 is designed to evaluate the efficacy, safety and pharmacokinetics (PK) of tofacitinib in pediatric participants with moderately to severely active UC. In the US patients

budesonide
mercaptopurine
pediatric ulcerative colitis
sulfasalazine
azathioprine
  • 0 views
  • 30 Apr, 2022
  • 42 locations
Efficiency of Methotrexate and Tofacitinib in Mild and Moderate Patients

mild, moderate, and severe, and prescribe methotrexate and tofacitinib randomly in mild and moderate patients, to observe the relatively better treatment strategy, facilitating better intervention

methotrexate
tofacitinib
  • 4 views
  • 01 Mar, 2022
  • 1 location