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Found 68 clinical trials
Featured trial
Preserving Beta-Cell Function with Tocilizumab in New Onset Type 1 Diabetes (the EXTEND Study)

Preserving Beta-Cell Function with Tocilizumab in New Onset Type 1 Diabetes (the EXTEND Study)

  • 3022 views
  • 23 Nov, 2020
  • 17 locations
Featured trial
(OSKIRA): A Phase III, Multi-centre, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study of Two Dosing Regimens of Investigational Product (Oral Agents) in Rheumatoid Arthritis Patients.

(OSKIRA): A Phase III, Multi-centre, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study of Two Dosing Regimens of Investigational Product (Oral Agents) in Rheumatoid Arthritis Patients.

  • 178 views
  • 08 Nov, 2020
  • 1 location
Tocilizumab in Children With ACP

dose of tocilizumab before they have SOC surgery of their tumor. The objective of this phase is to see if drug reaches the tumor. If phase 0 is favorable and shows that drug is penetrating the tumor

  • 0 views
  • 16 May, 2021
  • 1 location
Tocilizumab in Active Moderate-severe Graves' Orbitopathy

To treat patientis with active moderate-severe GO with the anti-IL6 receptor monoclonal antibody tocilizubam with the purpose of assesing the efficacy of therapy on active GO and on the proportion of patiens with inactivation and reactivation of disease (Primary Objective) Effect of therapy on disease progression, improvement of QoL, the …

  • 1 views
  • 16 May, 2021
  • 4 locations
A Prospective Study of Tocilizumab in the Treatment of Idiopathic Retroperitoneal Fibrosis

This is a prospective study to investigate the treatment response of Tocilizumab on patients with idiopathic retroperitoneal fibrosisIRPF. Methods: All the patients fulfilling diagnostic

  • 1 views
  • 28 Mar, 2021
  • 1 location
Adding Colchicine to Tocilizumab in Patients With Severe COVID-19 Pneumonia.

Colchicine acts upstream in the cytokines cascade by inhibiting the NLRP3 inflammasome while IL-6 receptor antagonists (tocilizumab) block the end result of the cytokines cascade. Hence, adding

  • 0 views
  • 10 Dec, 2021
  • 1 location
Ustekinumab for the Treatment of Relapse of Refractory Giant Cell Arteritis

, abatacept and tocilizumab have been shown to be effective during GCA. However, the therapeutic effect of the first two is modest. As for tocilizumab, its use has many limitations: suspensive effect, many

  • 0 views
  • 25 Jan, 2021
  • 1 location
Acute Response to Exercise in Patients With Rheumatoid Arthritis

controls will be recruited for an acute session of exercise. RA patients will be divided into 2 groups, according to the pharmacological treatment (tocilizumab or anti-TNF). The acute responses of insulin

tumor necrosis factor
tumour necrosis
tocilizumab
edema
  • 0 views
  • 04 Sep, 2021
  • 1 location
Randomised Evaluation of COVID-19 Therapy

), Convalescent plasma, Synthetic neutralizing antibodies (REGN-COV2), Tocilizumab, Aspirin, Baricitinib, Infliximab, Empagliflozin or Anakinra (children only) prevents death in patients with COVID-19.

pneumonia
ritonavir
hydroxychloroquine
covid-19
corticosteroids
  • 0 views
  • 23 Dec, 2021
  • 4 locations
Tocilizumab in Cardiac Transplantation

The purpose of this research study is to see if a study drug called Tocilizumab will, when given with standard anti-rejection medicines, lead to better heart transplantation outcomes at 1 year

hepatitis b
drug trials
prednisone
fluconazole
itraconazole
  • 62 views
  • 23 Mar, 2021
  • 27 locations