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Found 6 clinical trials
Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: TOBRA

The overall objective is to compare the effect of Vancomycin and Tobramycin powder combined (treatment) to Vancomycin powder (control) in the reduction of post-fixation infections of tibial

  • 11 Jul, 2021
  • 1 location
Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients (SuDDICU)

Introduction- Hospital acquired infections (HAI) are a major cause of morbidity and mortality and increase health care costs. Critically ill patients are particularly susceptible to these infections and have an even higher mortality. One intervention that has gained much interest in the medical literature for reducing infection rates and deaths …

antibiotic therapy
mechanical ventilation
critical illness
nosocomial infections
  • 01 May, 2022
  • 1 location
Inhaled Tobramycin in BPD

tobramycin administered to very preterm infants with BPD who are receiving invasive mechanical ventilation and have a pathogenic Gram-negative organism detected by tracheal aspirate culture.

  • 15 May, 2022
  • 1 location
Tobramycin Injection to Prevent Infection in Open Fractures

a novel synergistic combination of local aqueous tobramycin plus perioperative weight-based IV cephalosporin antibiotic prophylaxis will reduce the rate of FRI one year after OEF surgery. This in

  • 23 Mar, 2022
  • 1 location
Acute Application of Antibiotic Powder in Open Fracture Wounds

total cost of care. This study will be using an antibiotic called Vancomycin or Tobramycin in a powder form.

internal fixation
open fracture
  • 25 Aug, 2021
  • 2 locations
Antibiotic Loaded Calcium Sulfate RCT

This is a multi-centered, prospective, randomized controlled trial comparing current standard of care for defect management to placement of antibiotic loaded Stimulan as a bone void filler in patients undergoing treatment of infected tibial defects or infected tibial nonunions.

  • 24 Feb, 2022
  • 1 location