Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 71 clinical trials
Featured trial
(OSKIRA): A Phase III, Multi-centre, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study of Two Dosing Regimens of Investigational Product (Oral Agents) in Rheumatoid Arthritis Patients.

(OSKIRA): A Phase III, Multi-centre, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study of Two Dosing Regimens of Investigational Product (Oral Agents) in Rheumatoid Arthritis Patients.

  • 204 views
  • 08 Nov, 2020
  • 1 location
Guselkumab in Active Psoriatic Arthritis Participants With Inadequate Response/Intolerance to One Prior Anti-TNF Alpha Agent (SOLSTICE)

The purpose of this study is to evaluate the efficacy of guselkumab treatment in participants with active psoriatic arthritis (PsA) and inadequate response (IR) and/or intolerance to a prior anti-tumor necrosis factor (TNF) by assessing the reduction in signs and symptoms of PsA.

tumor necrosis factor
tumour necrosis
peripheral arthritis
psoriasis
rheumatoid nodules
  • 0 views
  • 02 Jul, 2022
  • 84 locations
Spondyloarthritis: Inducing Drug-free Remission by Early TNF-alpha Blockade (SPARTACUS)

The SPARTACUS study will explore the therapeutic efficacy of 2 different treatment strategies for patients suffering from peripheral Spondyloarthritis (pSpA), classified according to the "Assessment in SpondyloArthritis international Society" (ASAS) classification criteria; it will be set up as a 48-week, prospective, randomized, active-comparator controlled, double-blind, double-dummy, clinical trial with a …

  • 0 views
  • 25 Mar, 2022
  • 2 locations
A Study of Guselkumab and Golimumab Combination Therapy in Participants With Active Psoriatic Arthritis (AFFINITY)

prior anti-tumor necrosis factor-alpha (anti-TNF-alpha) therapy by assessing clinical response compared with guselkumab monotherapy.

tumor necrosis factor
adalimumab
tumour necrosis
psoriasis
peripheral arthritis
  • 7 views
  • 01 Jul, 2022
  • 16 locations
A Study to Evaluate the Safety and Effectiveness of Etanercept in Treating Lichen Planus on the Oral Mucosa or Skin

The purpose of this study is to determine the safety and efficacy of etanercept (also known as Enbrel) in the treatment of moderate to severe lichen planus.

  • 21 views
  • 07 Nov, 2020
  • 1 location
Probiotic Modulation of Oral Microbiota (PROROBIOTICS)

Targeting human microbiota, in particular those of the gastrointestinal tract, by means of prebiotics, probiotics, symbiotics or antibiotics has gained interest for its potential in the management of human health. Oral bacterial communities have been extensively studied over the last decade both in normal and pathological states; however, little data …

Accepts healthy volunteers
  • 0 views
  • 09 Apr, 2022
Effect of Physiologic Hyperglucogonemia on Adipocyte Metabolism (Glucagon)

Purpose/Objectives: To investigate the effect of hyperglucagonemia on insulin action, particularly on adipose tissue. Research Design/Plan: Normal glucose tolerant subjects will be studied. Study subjects will receive a continuous glucagon infusion for 12 hours. Following glucagon infusion, subjects will receive prime-continuous tracer infusions for additional 4 hours to measure adipocyte …

Accepts healthy volunteers
  • 3 views
  • 01 Mar, 2022
  • 2 locations
Zinc Chromium Vitamin C and Copper Combination Supplement for Prediabetes Progression

Currently, the incidence of diabetes mellitus is increasing worldwide. People with prediabetes have higher risk to develop diabetes mellitus type 2. Several studies have proven that Zinc and Chromium are minerals that contribute to decreasing the level of blood glucose and insulin resistance. In addition, vitamin C also contributes in …

hemoglobin a1c
insulin
fasting
insulin resistance
glucose tolerance test
  • 0 views
  • 31 Aug, 2021
  • 1 location
COVID-OUT: Early Outpatient Treatment for SARS-CoV-2 Infection (COVID-19)

The purpose of this trial is to understand whether: Metformin vs fluvoxamine vs ivermectin vs metformin+fluvoxamine vs metformin+ivermectin is superior to placebo in non-hospitalized adults with SARS-CoV-2 disease for preventing Covid-19 disease progression. To understand if the active treatment arms are superior to placebo in improving viral load, serologic markers …

  • 21 views
  • 14 Mar, 2022
  • 8 locations
Improving Nutrition and Physical Activity for Colorectal Cancer Survivors (Tools To Be Fit)

This clinical trial studies the effect of four different intervention components "tools" on body weight, nutrition, and physical activity in colorectal cancer survivors. Studies indicate that people with colorectal cancer whose nutrition and physical activity habits are consistent with the American Cancer Society's Nutrition and Physical Activity Guidelines may have …

  • 0 views
  • 12 Nov, 2021
  • 2 locations